1K8Q

CRYSTAL STRUCTURE OF DOG GASTRIC LIPASE IN COMPLEX WITH A PHOSPHONATE INHIBITOR

Summary for 1K8Q

• Entry DOI: 10.2210/pdb1k8q/pdb
• Related: 1HLG
• Descriptor: Triacylglycerol lipase, gastric, 2-acetamido-2-deoxy-beta-D-glucopyranose, octyl beta-D-glucopyranoside, ... (5 entities in total)
• Functional Keywords: apha beta hydrolase fold, hydrolase
• Biological source: Canis lupus familiaris (dog)
• Cellular location: Secreted: P80035
• Total number of polymer chains: 2
• Total formula weight: 88774.90

Authors

Roussel, A.,Miled, N.,Berti-Dupuis, L.,Riviere, M.,Spinelli, S.,Berna, P.,Gruber, V.,Verger, R.,Cambillau, C. (deposition date: 2001-10-25, release date: 2002-03-06, Last modification date: 2023-08-16)

• Primary citation: Roussel, A.,Miled, N.,Berti-Dupuis, L.,Riviere, M.,Spinelli, S.,Berna, P.,Gruber, V.,Verger, R.,Cambillau, C.; Crystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitor.; J.Biol.Chem., 277:2266-2274, 2002; PubMed: 11689574; DOI: 10.1074/jbc.M109484200

Experimental method

X-RAY DIFFRACTION (2.7 Å)