7P9T
Crystal structure of CD73 in complex with dCMP in the open form
Summary for 7P9T
Entry DOI | 10.2210/pdb7p9t/pdb |
Descriptor | 5'-nucleotidase, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | ecto-5'-nucleotidase, en, substrate, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 60942.43 |
Authors | Scaletti, E.R.,Strater, N. (deposition date: 2021-07-27, release date: 2021-10-13, Last modification date: 2024-01-31) |
Primary citation | Scaletti, E.,Huschmann, F.U.,Mueller, U.,Weiss, M.S.,Strater, N. Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17:693-704, 2021 Cited by PubMed: 34403084DOI: 10.1007/s11302-021-09802-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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