5L2H
Crystal Structure of W26A mutant of anti-EGFR Centyrin P54AR4-83v2
Summary for 5L2H
Entry DOI | 10.2210/pdb5l2h/pdb |
Descriptor | Centyrin, GLYCEROL (3 entities in total) |
Functional Keywords | scaffold protein, fibronectin type iii, beta sandwich, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 46067.21 |
Authors | Cardoso, R.M.F.,Goldberg, S.D.,O Neil, K.T.,Gilliland, G.L. (deposition date: 2016-08-01, release date: 2016-11-02, Last modification date: 2024-03-06) |
Primary citation | Goldberg, S.D.,Cardoso, R.M.,Lin, T.,Spinka-Doms, T.,Klein, D.,Jacobs, S.A.,Dudkin, V.,Gilliland, G.,O'Neil, K.T. Engineering a targeted delivery platform using Centyrins. Protein Eng. Des. Sel., 29:563-572, 2016 Cited by PubMed: 27737926DOI: 10.1093/protein/gzw054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8013 Å) |
Structure validation
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