3CDR
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![BU of 3cdr by Molmil](/molmil-images/mine/3cdr) | R96Q Mutant of wildtype phage T4 lysozyme at 298 K | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Lysozyme | Authors: | Mooers, B.H.M. | Deposit date: | 2008-02-27 | Release date: | 2009-02-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme. Protein Sci., 18, 2009
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3CDO
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3U5T
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![BU of 3u5t by Molmil](/molmil-images/mine/3u5t) | The crystal structure of 3-oxoacyl-[acyl-carrier-protein] reductase from Sinorhizobium meliloti | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] reductase | Authors: | Zhang, Z, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, LaFleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2011-10-11 | Release date: | 2011-11-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of 3-oxoacyl-[acyl-carrier-protein] reductase from Sinorhizobium meliloti To be Published
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1Q7A
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![BU of 1q7a by Molmil](/molmil-images/mine/1q7a) | Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution | Descriptor: | 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, METHANOL, Phospholipase A2 VRV-PL-VIIIa, ... | Authors: | Singh, N, Jabeen, T, Sharma, S, Singh, T.P. | Deposit date: | 2003-08-17 | Release date: | 2004-05-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution. Biochemistry, 43, 2004
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3U6S
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![BU of 3u6s by Molmil](/molmil-images/mine/3u6s) | MutM set 1 TpG | Descriptor: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*AP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*TP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
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3CBD
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3CD0
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![BU of 3cd0 by Molmil](/molmil-images/mine/3cd0) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | Descriptor: | (3R,5R)-7-{2-[(4-fluorobenzyl)carbamoyl]-4-(4-fluorophenyl)-1-(1-methylethyl)-1H-imidazol-5-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Authors: | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | Deposit date: | 2008-02-26 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
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3CD7
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![BU of 3cd7 by Molmil](/molmil-images/mine/3cd7) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | Descriptor: | (3R,5R)-7-[5-(ANILINOCARBONYL)-3,4-BIS(4-FLUOROPHENYL)-1-ISOPROPYL-1H-PYRROL-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Authors: | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | Deposit date: | 2008-02-26 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
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3CDB
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![BU of 3cdb by Molmil](/molmil-images/mine/3cdb) | Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors | Descriptor: | (3R,5R)-7-{3-[(4-carbamoylphenyl)sulfamoyl]-4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-pyrrol-1-yl}-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Authors: | Pavlovsky, A, Sarver, R.W, Harris, M.S, Finzel, B.C. | Deposit date: | 2008-02-26 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme a reductase. J.Med.Chem., 51, 2008
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3TIK
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![BU of 3tik by Molmil](/molmil-images/mine/3tik) | Sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in complex with the tipifarnib derivative 6-((4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl)-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one | Descriptor: | 6-[(R)-(4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl]-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one, PROTOPORPHYRIN IX CONTAINING FE, sterol 14-alpha demethylase (CYP51) | Authors: | Hargrove, T.Y, Wawrzak, Z, Kraus, J.M, Gelb, M.H, Buckner, F.S, Waterman, M.R, Lepesheva, G.I. | Deposit date: | 2011-08-20 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Pharmacological characterization, structural studies, and in vivo activities of anti-chagas disease lead compounds derived from tipifarnib. Antimicrob.Agents Chemother., 56, 2012
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3AHT
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![BU of 3aht by Molmil](/molmil-images/mine/3aht) | Crystal structure of rice BGlu1 E176Q mutant in complex with laminaribiose | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... | Authors: | Chuenchor, W, Pengthaisong, S, Robinson, R.C, Yuvaniyama, J, Svasti, J, Ketudat Cairns, J.R. | Deposit date: | 2010-04-29 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase J.Struct.Biol., 173, 2011
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3AIR
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![BU of 3air by Molmil](/molmil-images/mine/3air) | Crystal structure of beta-glucosidase in wheat complexed with 2-deoxy-2-fluoroglucoside and dinitrophenol | Descriptor: | 2,4-DINITROPHENOL, 2-deoxy-2-fluoro-alpha-D-glucopyranose, Beta-glucosidase | Authors: | Sue, M, Nakamura, C, Miyamoto, T, Yajima, S. | Deposit date: | 2010-05-18 | Release date: | 2011-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Active-site architecture of benzoxazinone-glucoside beta-D-glucosidases in Triticeae Plant Sci., 180, 2011
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3AHZ
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![BU of 3ahz by Molmil](/molmil-images/mine/3ahz) | Crystal structure of beta-glucosidase from termite Neotermes koshunensis in complex with Tris | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase, GLYCEROL | Authors: | Jeng, W.-Y, Liu, C.-I, Wang, A.H.-J. | Deposit date: | 2010-05-06 | Release date: | 2010-08-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Structural and functional analysis of three beta-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensis J.Struct.Biol., 173, 2011
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3AMG
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![BU of 3amg by Molmil](/molmil-images/mine/3amg) | Crystal structures of Thermotoga maritima Cel5A in complex with Cellobiose substrate, mutant form | Descriptor: | Endoglucanase, beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Wu, T.H, Huang, C.H, Ko, T.P, Lai, H.L, Ma, Y, Cheng, Y.S, Liu, J.R, Guo, R.T. | Deposit date: | 2010-08-20 | Release date: | 2011-08-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose Biochim.Biophys.Acta, 1814, 2011
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3AOG
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3SOI
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![BU of 3soi by Molmil](/molmil-images/mine/3soi) | Crystallographic structure of Bacillus licheniformis beta-lactamase W210F/W229F/W251F at 1.73 angstrom resolution | Descriptor: | Beta-lactamase, CITRIC ACID | Authors: | Acierno, J.P, Capaldi, S, Risso, V.A, Monaco, H.L, Ermacora, M.R. | Deposit date: | 2011-06-30 | Release date: | 2011-12-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.729 Å) | Cite: | X-ray evidence of a native state with increased compactness populated by tryptophan-less B. licheniformis beta-lactamase. Protein Sci., 21, 2012
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3STH
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![BU of 3sth by Molmil](/molmil-images/mine/3sth) | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Toxoplasma gondii | Descriptor: | 1,2-ETHANEDIOL, Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Seattle Structural Genomics Center for Infectious Disease (SSGCID), Staker, B.L, Edwards, T.E, Sankaran, B. | Deposit date: | 2011-07-10 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Membrane skeletal association and post-translational allosteric regulation of Toxoplasma gondii GAPDH1. Mol.Microbiol., 103, 2017
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3AOF
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![BU of 3aof by Molmil](/molmil-images/mine/3aof) | Crystal structures of Thermotoga maritima Cel5A in complex with Mannotriose substrate | Descriptor: | Endoglucanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose | Authors: | Wu, T.H, Huang, C.H, Ko, T.P, Lai, H.L, Ma, Y, Cheng, Y.S, Liu, J.R, Guo, R.T. | Deposit date: | 2010-09-27 | Release date: | 2011-08-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.288 Å) | Cite: | Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose Biochim.Biophys.Acta, 1814, 2011
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3AHV
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![BU of 3ahv by Molmil](/molmil-images/mine/3ahv) | Semi-active E176Q mutant of rice bglu1 covalent complex with 2-deoxy-2-fluoroglucoside | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-deoxy-2-fluoro-alpha-D-glucopyranose, Beta-glucosidase 7, ... | Authors: | Chuenchor, W, Pengthaisong, S, Robinson, R.C, Yuvaniyama, J, Svasti, J, Ketudat Cairns, J.R. | Deposit date: | 2010-04-30 | Release date: | 2010-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | The structural basis of oligosaccharide binding by rice BGlu1 beta-glucosidase J.Struct.Biol., 173, 2011
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6CUF
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![BU of 6cuf by Molmil](/molmil-images/mine/6cuf) | Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody vFP1.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Acharya, P, Carragher, B, Potter, C.S, Kwong, P.D. | Deposit date: | 2018-03-26 | Release date: | 2018-07-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV. PLoS Pathog., 14, 2018
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6CKA
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![BU of 6cka by Molmil](/molmil-images/mine/6cka) | Crystal Structure of Paratox | Descriptor: | Paratox | Authors: | Prehna, G. | Deposit date: | 2018-02-27 | Release date: | 2018-11-14 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1.559 Å) | Cite: | The conserved mosaic prophage protein paratox inhibits the natural competence regulator ComR in Streptococcus. Sci Rep, 8, 2018
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3T0A
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![BU of 3t0a by Molmil](/molmil-images/mine/3t0a) | E. coli (LacZ) beta-galactosidase (S796T) | Descriptor: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E. | Deposit date: | 2011-07-19 | Release date: | 2012-01-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Arch.Biochem.Biophys., 517, 2012
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3AMN
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![BU of 3amn by Molmil](/molmil-images/mine/3amn) | E134C-Cellobiose complex of cellulase 12A from thermotoga maritima | Descriptor: | Endo-1,4-beta-glucanase, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Cheng, Y.-S, Ko, T.-P, Liu, J.-R, Guo, R.-T. | Deposit date: | 2010-08-20 | Release date: | 2011-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritima Proteins, 79, 2011
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3T37
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![BU of 3t37 by Molmil](/molmil-images/mine/3t37) | Crystal structure of pyridoxine 4-oxidase from Mesorbium loti | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable dehydrogenase | Authors: | Mugo, A.N, Kobayashi, J, Mikami, B, Ohnishi, K, Yagi, T. | Deposit date: | 2011-07-25 | Release date: | 2012-08-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.193 Å) | Cite: | Structure biology and crystallization communication TO BE PUBLISHED
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5PZL
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![BU of 5pzl by Molmil](/molmil-images/mine/5pzl) | CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-({3-[1-(2-CYCLOPROPYLETHYL)-6-FLUORO-4-HYDROXY-2-OXO-1,2-DIHYDROQUINOLIN-3-YL]-1,1-DIOXO-1,4-DIHYDRO-1LAMBDA~6~,2,4-BENZOTHIADIAZIN-7-YL}OXY)ACETAMIDE | Descriptor: | (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, 2-({3-[1-(2-cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxo-1,4-dihydro-1lambda~6~,2,4-benzothiadiazin-7-yl}oxy)acetamide, RNA-directed RNA polymerase, ... | Authors: | Sheriff, S. | Deposit date: | 2017-02-27 | Release date: | 2017-05-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. J. Med. Chem., 60, 2017
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