6FMC
| Neuropilin1-b1 domain in complex with EG01377, 0.9 Angstrom structure | 分子名称: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1 | 著者 | Yelland, T, Djordjevic, S, Fotinou, K, Selwood, D, Zachary, I, Frankel, P. | 登録日 | 2018-01-30 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
|
|
2PQS
| |
6OE2
| |
7O1N
| |
8PFE
| |
7P5U
| |
4XZU
| |
5JGI
| X-ray structure of neuropilin-1 b1 domain complexed with M45 compound | 分子名称: | N-ALPHA-L-ACETYL-ARGININE, Neuropilin-1 | 著者 | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | 登録日 | 2016-04-20 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
|
|
5JGQ
| X-ray structure of neuropilin-1 b1 domain complexed with Arg-7 ligand. | 分子名称: | DIMETHYL SULFOXIDE, Neuropilin-1, N~2~-(benzenecarbonyl)-L-arginine | 著者 | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | 登録日 | 2016-04-20 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
|
|
5ZU6
| |
5DN2
| Human NRP2 b1 domain in complex with the peptide corresponding to the C-terminus of VEGF-A | 分子名称: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, Neuropilin-2, ... | 著者 | Tsai, Y.C.I, Frankel, P, Fotinou, C, Rana, R, Zachary, I, Djordjevic, S. | 登録日 | 2015-09-09 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket. Febs J., 283, 2016
|
|
4RN5
| B1 domain of human Neuropilin-1 with acetate ion in a ligand-binding site | 分子名称: | ACETATE ION, GLYCEROL, Neuropilin-1, ... | 著者 | Allerston, C.K, Yelland, T.S, Jarvis, A, Jenkins, K, Winfield, N, Cheng, L, Jia, H, Zachary, I, Selwood, D.L, Djordjevic, S. | 登録日 | 2014-10-23 | 公開日 | 2015-10-28 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Conserved water molecules in a ligand-binding site of neuropilin-1 To be Published
|
|
4TXW
| Crystal structure of CBM32-4 from the Clostridium perfringens NagH | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Hyaluronoglucosaminidase | 著者 | Grondin, J.M, Ficko-Blean, E, Boraston, A.B, Smith, S.P. | 登録日 | 2014-07-07 | 公開日 | 2015-12-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Solution Structure and Dynamics of Full-length GH84A, a multimodular B-N-acetylglucosaminidase from Clostridium perfringens To Be Published
|
|
5N6W
| Retinoschisin R141H Mutant | 分子名称: | Retinoschisin | 著者 | Ramsay, E.P, Collins, R.F, Owens, T.W, Siebert, C.A, Jones, R.P.O, Roseman, A, Wang, T, Baldock, C. | 登録日 | 2017-02-16 | 公開日 | 2017-04-12 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural analysis of X-linked retinoschisis mutations reveals distinct classes which differentially effect retinoschisin function Human Molecular Genetics, 25, 2016
|
|
5DQ0
| Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Tsai, Y.I, Rana, R.R, Zachary, I, Djordjevic, S. | 登録日 | 2015-09-14 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human neuropilin-2 b1 domain with novel and unique zinc binding site To Be Published
|
|
5Y4M
| Discoidin domain of human CASPR2 | 分子名称: | 1,2-ETHANEDIOL, human CASPR2 Disc domain | 著者 | Liu, H, Xu, F, Zhang, J, Liang, W. | 登録日 | 2017-08-04 | 公開日 | 2018-08-08 | 最終更新日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Structural mapping of hot spots within human CASPR2 discoidin domain for autoantibody recognition. J. Autoimmun., 96, 2019
|
|
6FMF
| Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure | 分子名称: | (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid | 著者 | Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P. | 登録日 | 2018-01-31 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.811 Å) | 主引用文献 | Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
|
|
6TJT
| Neuropilin2-b1 domain in a complex with the C-terminal VEGFC peptide | 分子名称: | 1,2-ETHANEDIOL, Neuropilin-2, SULFATE ION, ... | 著者 | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | 登録日 | 2019-11-26 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | NRP2-b1 domain in a complex with the C-terminal VEGFC peptide To Be Published
|
|
6TKK
| Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide | 分子名称: | 1,2-ETHANEDIOL, ACE-ARG-PRO-GLN-PRO-ARG, Neuropilin-1 | 著者 | Eldrid, C, Yu, L, Yelland, T, Fotinou, C, Djordjevic, S. | 登録日 | 2019-11-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Neuropilin 1-b1 domain in a complex with the C-terminal VEGFB186 peptide To Be Published
|
|
2Z4F
| Solution structure of the Discoidin Domain of DDR2 | 分子名称: | Discoidin domain-containing receptor 2 | 著者 | Ichikawa, O, Osawa, M, Nishida, N, Goshima, N, Nomura, N, Shimada, I. | 登録日 | 2007-06-16 | 公開日 | 2007-09-04 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of the collagen-binding mode of discoidin domain receptor 2 Embo J., 26, 2007
|
|
7RGA
| |
7AZB
| Structure of DDR2 DS domain in complex with VHH | 分子名称: | Discoidin domain-containing receptor 2, VHH | 著者 | Talagas, A, Nawrotek, A, Arrial, A, Vuillard, L.M, Miallau, L. | 登録日 | 2020-11-16 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structure of DDR2 DS domain in complex with VHH To Be Published
|
|
2WUH
| Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide | 分子名称: | COLLAGEN PEPTIDE, DISCOIDIN DOMAIN RECEPTOR 2 | 著者 | Carafoli, F, Bihan, D, Stathopoulos, S, Konitsiotis, A.D, Kvansakul, M, Farndale, R.W, Leitinger, B, Hohenester, E. | 登録日 | 2009-10-05 | 公開日 | 2009-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2 Structure, 17, 2009
|
|
7S0P
| Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine | 分子名称: | Coagulation factor VIII, PHOSPHOSERINE | 著者 | Peters, S.C, Childers, K.C, Wo, S.W, Brison, C.M, Swanson, C.D, Spiegel, P.C. | 登録日 | 2021-08-30 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII. Front Mol Biosci, 9, 2022
|
|
1TVG
| X-ray structure of human PP25 gene product, HSPC034. Northeast Structural Genomics Target HR1958. | 分子名称: | CALCIUM ION, LOC51668 protein, SAMARIUM (III) ION | 著者 | Kuzin, A.P, Vorobiev, S.M, Lee, I, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-06-29 | 公開日 | 2004-11-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Improving NMR protein structure quality by Rosetta refinement: a molecular replacement study. Proteins, 75, 2009
|
|