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PDB: 277 results

4LK1
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BU of 4lk1 by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B, Darst, S.A.
Deposit date:2013-07-05
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8369 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LLG
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BU of 4llg by Molmil
Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex
Descriptor: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2013-07-09
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.7936 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LJZ
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BU of 4ljz by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B, Darst, S.A.
Deposit date:2013-07-05
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5871 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4LK0
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BU of 4lk0 by Molmil
Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex
Descriptor: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2013-07-05
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.9103 Å)
Cite:Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
7KHE
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BU of 7khe by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp
Descriptor: CHAPSO, DNA (46-MER), DNA (54-MER), ...
Authors:Shin, Y, Qayyum, M.Z, Murakami, K.S.
Deposit date:2020-10-21
Release date:2020-12-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
7KHB
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BU of 7khb by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter open complex
Descriptor: CHAPSO, DNA (60-MER), DNA (64-MER), ...
Authors:Shin, Y, Qayyum, M.Z, Murakami, K.S.
Deposit date:2020-10-20
Release date:2020-10-28
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
4MEX
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BU of 4mex by Molmil
Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H.
Deposit date:2013-08-27
Release date:2014-05-21
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.902 Å)
Cite:Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
7KHC
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BU of 7khc by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter closed complex
Descriptor: CHAPSO, DNA (18 MER), DNA (63-MER), ...
Authors:Shin, Y, Qayyum, M.Z, Murakami, K.S.
Deposit date:2020-10-20
Release date:2020-10-28
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
7KHI
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BU of 7khi by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp
Descriptor: CHAPSO, DNA (28-MER), DNA (36-MER), ...
Authors:Shin, Y, Qayyum, M.Z, Murakami, K.S.
Deposit date:2020-10-21
Release date:2020-10-28
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
7KIF
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Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor
Descriptor: DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2020-10-23
Release date:2021-04-21
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
7KIN
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BU of 7kin by Molmil
Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter
Descriptor: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2020-10-23
Release date:2021-04-21
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
7KIM
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BU of 7kim by Molmil
Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor
Descriptor: DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M, Darst, S.A, Campbell, E.A.
Deposit date:2020-10-23
Release date:2021-04-21
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
4MEY
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BU of 4mey by Molmil
Crystal structure of Escherichia coli RNA polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H.
Deposit date:2013-08-27
Release date:2014-05-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.948 Å)
Cite:Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
4X8K
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BU of 4x8k by Molmil
Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2
Descriptor: 1,2-ETHANEDIOL, RNA polymerase sigma factor SigA, RNA polymerase-binding protein RbpA, ...
Authors:Hubin, E.A, Flack, J.E, Tabib-Salazar, A, Paget, M.S, Darst, S.A, Campbell, E.A.
Deposit date:2014-12-10
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XLS
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BU of 4xls by Molmil
Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream fork promoter.
Descriptor: CarD-like transcriptional regulator, DNA (30-MER), DNA (5'-D(P*GP*CP*AP*CP*AP*AP*TP*TP*TP*AP*AP*CP*AP*CP*TP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3'), ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-13
Release date:2015-09-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.01 Å)
Cite:CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
4XLR
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BU of 4xlr by Molmil
Crystal structure of T.aquaticus transcription initiation complex with CarD containing bubble promoter and RNA
Descriptor: CarD-like transcriptional regulator, DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-13
Release date:2015-09-23
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
4XLN
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BU of 4xln by Molmil
Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and RNA
Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-13
Release date:2015-09-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015
4XLQ
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BU of 4xlq by Molmil
Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11 base-paired) promoter
Descriptor: DNA (26-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-13
Release date:2015-09-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (4.6 Å)
Cite:Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015
4XSZ
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BU of 4xsz by Molmil
Crystal structure of CBR 9393 bound to Escherichia coli RNA polymerase holoenzyme
Descriptor: 4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]-N-[2-(piperazin-1-yl)ethyl]-2-(trifluoromethyl)aniline, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-22
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.683 Å)
Cite:CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XSX
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BU of 4xsx by Molmil
Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-22
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.708 Å)
Cite:CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XLP
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BU of 4xlp by Molmil
Crystal structure of T.aquaticus transcription initiation complex containing upstream fork promoter
Descriptor: DNA (25-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-13
Release date:2015-09-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of a bacterial RNA polymerase holoenzyme open promoter complex.
Elife, 4, 2015
4XSY
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BU of 4xsy by Molmil
Crystal structure of CBR 9379 bound to Escherichia coli RNA polymerase holoenzyme
Descriptor: 3-{[(2,6-dichlorophenyl)carbamoyl]amino}-N-hydroxy-N'-phenyl-5-(trifluoromethyl)benzenecarboximidamide, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Bae, B, Darst, S.A.
Deposit date:2015-01-22
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.007 Å)
Cite:CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YLP
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BU of 4ylp by Molmil
E. coli Transcription Initiation Complex - 16-bp spacer and 5-nt RNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, Steitz, T.A.
Deposit date:2015-03-05
Release date:2015-04-22
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
4YG2
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BU of 4yg2 by Molmil
X-ray crystal structur of Escherichia coli RNA polymerase sigma70 holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murakami, K.S.
Deposit date:2015-02-25
Release date:2015-03-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:X-ray crystal structure of Escherichia coli RNA polymerase sigma70 holoenzyme
J. Biol. Chem., 288, 2013
4YLO
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BU of 4ylo by Molmil
E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, Steitz, T.A.
Deposit date:2015-03-05
Release date:2015-04-22
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (6 Å)
Cite:Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015

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PDB entries from 2024-05-15

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