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PDB: 168 件

4U3F
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Cytochrome bc1 complex from chicken with designed inhibitor bound
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CARDIOLIPIN, ...
著者Huang, L.-S, Zhu, X.-L, Yang, G.F, Berry, E.A.
登録日2014-07-21
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2312 Å)
主引用文献Rational Design of Highly Potent and Slow-Binding Cytochrome bc1 Inhibitor as Fungicide by Computational Substitution Optimization
Sci Rep, 5, 2015
1EZV
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STRUCTURE OF THE YEAST CYTOCHROME BC1 COMPLEX CO-CRYSTALLIZED WITH AN ANTIBODY FV-FRAGMENT
分子名称: 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, CYTOCHROME B, CYTOCHROME C1, ...
著者Hunte, C, Koepke, J, Lange, C, Rossmanith, T, Michel, H.
登録日2000-05-12
公開日2001-05-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.
Structure Fold.Des., 8, 2000
2IBZ
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Yeast Cytochrome BC1 Complex with Stigmatellin
分子名称: 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, Cytochrome b, Cytochrome c1, ...
著者Hunte, C.
登録日2006-09-12
公開日2007-03-20
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Comparison of Stigmatellin Conformations, Free and Bound to the Photosynthetic Reaction Center and the Cytochrome bc(1) Complex.
J.Mol.Biol., 368, 2007
3TGU
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BU of 3tgu by Molmil
Cytochrome bc1 complex from chicken with pfvs-designed moa inhibitor bound
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ...
著者Huang, L.-S, Yang, G.-F, Berry, E.A.
登録日2011-08-17
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Computational discovery of picomolar Q(o) site inhibitors of cytochrome bc1 complex.
J.Am.Chem.Soc., 134, 2012
4H44
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2.70 A Cytochrome b6f Complex Structure From Nostoc PCC 7120
分子名称: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (7R,17E)-4-HYDROXY-N,N,N,7-TETRAMETHYL-7-[(8E)-OCTADEC-8-ENOYLOXY]-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOS-17-EN-1-AMINIUM 4-OXIDE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ...
著者Hasan, S.S, Yamashita, E, Baniulis, D, Cramer, W.A.
登録日2012-09-16
公開日2013-02-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Quinone-dependent proton transfer pathways in the photosynthetic cytochrome b6f complex
Proc.Natl.Acad.Sci.USA, 110, 2013
6T0B
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The III2-IV(5B)2 respiratory supercomplex from S. cerevisiae
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ...
著者Marechal, A, Pinotsis, N, Hartley, A.
登録日2019-10-02
公開日2020-04-22
最終更新日2020-05-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
6T15
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The III2-IV(5B)1 respiratory supercomplex from S. cerevisiae
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CARDIOLIPIN, COPPER (II) ION, ...
著者Marechal, A, Pinotsis, N, Hartley, A.
登録日2019-10-03
公開日2020-04-22
最終更新日2020-05-06
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Rcf2 revealed in cryo-EM structures of hypoxic isoforms of mature mitochondrial III-IV supercomplexes.
Proc.Natl.Acad.Sci.USA, 117, 2020
5NMI
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Cytochrome bc1 bound to the inhibitor MJM170
分子名称: (4aS)-2-methyl-3-(4-phenoxyphenyl)-5,6,7,8-tetrahydroquinolin-4(4aH)-one, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ARG-ASN-TRP-VAL-PRO-THR-ALA-GLN-LEU-TRP-GLY-ALA-VAL-GLY-ALA-VAL-GLY-LEU-VAL-SER-ALA-THR, ...
著者Capper, N.J, Antonyuk, S.V, Hasnain, S.S.
登録日2017-04-05
公開日2017-06-14
最終更新日2018-12-19
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections.
Sci Rep, 6, 2016
4I7Z
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Crystal structure of cytochrome b6f in DOPG, with disordered Rieske Iron-Sulfur Protein soluble domain
分子名称: (2R)-3-{[(R)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-[(6Z)-tridec-6-enoyloxy]propyl (9Z)-octadec-9-enoate, (2S)-3-(acetyloxy)-2-hydroxypropyl 6-deoxy-6-sulfo-beta-D-glucopyranoside, Apocytochrome f, ...
著者Hasan, S.S, Stofleth, J.T, Yamashita, E, Cramer, W.A.
登録日2012-12-01
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Lipid-induced conformational changes within the cytochrome b6f complex of oxygenic photosynthesis.
Biochemistry, 52, 2013
5OKD
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BU of 5okd by Molmil
Crystal structure of bovine Cytochrome bc1 in complex with inhibitor SCR0911.
分子名称: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Amporndanai, K, O'Neill, P.M, Hasnain, S.S, Antonyuk, S.V.
登録日2017-07-25
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
IUCrJ, 5, 2018
1VF5
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BU of 1vf5 by Molmil
Crystal Structure of Cytochrome b6f Complex from M.laminosus
分子名称: (7R,17E)-4-HYDROXY-N,N,N,7-TETRAMETHYL-7-[(8E)-OCTADEC-8-ENOYLOXY]-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOS-17-EN-1-AMINIUM 4-OXIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, 8-HYDROXY-5,7-DIMETHOXY-3-METHYL-2-TRIDECYL-4H-CHROMEN-4-ONE, ...
著者Kurisu, G, Zhang, H, Smith, J.L, Cramer, W.A.
登録日2004-04-08
公開日2004-04-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Cytochrome B6F Complex of Oxygenic Photosynthesis: Tuning the Cavity
Science, 302, 2003
6ZFU
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Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor RKA066
分子名称: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Amporndanai, K, O'Neill, P.M, Hong, W.D, Amewu, R.K, Pidathala, C, Berry, N.G, Biagini, G.A, Leung, S.C, Hasnain, S.S, Antonyuk, S.V.
登録日2020-06-17
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials
To Be Published
6ZFT
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BU of 6zft by Molmil
Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor CK-2-68
分子名称: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Amporndanai, K, O'Neill, P.M, Hong, W.D, Amewu, R.K, Pidathala, C, Berry, N.G, Biagini, G.A, Leung, S.C, Hasnain, S.S, Antonyuk, S.V.
登録日2020-06-17
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials
To Be Published
6ZFS
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Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor WDH-1U-4
分子名称: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Amporndanai, K, O'Neill, P.M, Hong, W.D, Amewu, R.K, Pidathala, C, Berry, N.G, Biagini, G.A, Leung, S.C, Hasnain, S.S, Antonyuk, S.V.
登録日2020-06-17
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials
To Be Published
5XTH
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BU of 5xth by Molmil
Cryo-EM structure of human respiratory supercomplex I1III2IV1
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ...
著者Gu, J, Wu, M, Yang, M.
登録日2017-06-19
公開日2017-09-13
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
6GIQ
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Saccharomyces cerevisiae respiratory supercomplex III2IV
分子名称: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate, (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate, ...
著者Rathore, S, Berndtsson, J, Conrad, J, Ott, M.
登録日2018-05-15
公開日2019-01-02
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Cryo-EM structure of the yeast respiratory supercomplex.
Nat. Struct. Mol. Biol., 26, 2019
5XTI
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Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ...
著者Gu, J, Wu, M, Yang, M.
登録日2017-06-19
公開日2017-09-13
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (17.4 Å)
主引用文献Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
5XTE
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Cryo-EM structure of human respiratory complex III (cytochrome bc1 complex)
分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, ...
著者Gu, J, Wu, M, Yang, M.
登録日2017-06-19
公開日2017-08-30
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Cell, 170, 2017
8E73
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Vigna radiata supercomplex I+III2 (full bridge)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Maldonado, M, Letts, J.A.
登録日2022-08-23
公開日2023-01-11
最終更新日2023-02-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Plant-specific features of respiratory supercomplex I + III 2 from Vigna radiata.
Nat.Plants, 9, 2023
6HU9
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III2-IV2 mitochondrial respiratory supercomplex from S. cerevisiae
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, CALCIUM ION, ...
著者Hartley, A.M, Pinotsis, N, Marechal, A.
登録日2018-10-05
公開日2018-12-26
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structure of yeast cytochrome c oxidase in a supercomplex with cytochrome bc1.
Nat. Struct. Mol. Biol., 26, 2019
6HAW
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BU of 6haw by Molmil
Crystal structure of bovine cytochrome bc1 in complex with 2-pyrazolyl quinolone inhibitor WDH2G7
分子名称: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ...
著者Amporndanai, K, Hong, W.D, O'Neill, P.M, Hasnain, S.S, Antonyuk, S.V.
登録日2018-08-08
公開日2019-01-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Potent Antimalarial 2-Pyrazolyl Quinolonebc1(Qi) Inhibitors with Improved Drug-like Properties.
ACS Med Chem Lett, 9, 2018
1BGY
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BU of 1bgy by Molmil
CYTOCHROME BC1 COMPLEX FROM BOVINE
分子名称: CYTOCHROME BC1 COMPLEX, FE2/S2 (INORGANIC) CLUSTER, HEME C, ...
著者Iwata, S, Lee, J.W, Okada, K, Lee, J.K, Iwata, M, Ramaswamy, S, Jap, B.K.
登録日1998-06-02
公開日1999-01-06
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Science, 281, 1998
8EC0
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BU of 8ec0 by Molmil
III2IV respiratory supercomplex from Saccharomyces cerevisiae cardiolipin-lacking mutant
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ...
著者Hryc, C.F, Mileykovskaya, E, Baker, M, Dowhan, W.
登録日2022-08-31
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex.
Nat Commun, 14, 2023
8E7S
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III2IV2 respiratory supercomplex from Saccharomyces cerevisiae with 4 bound UQ6
分子名称: (5S,11R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-4,6,10,12,16-pentaoxa-5,11-diphosphaoctadec-1-yl pentadecanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 5-(3,7,11,15,19,23-HEXAMETHYL-TETRACOSA-2,6,10,14,18,22-HEXAENYL)-2,3-DIMETHOXY-6-METHYL-BENZENE-1,4-DIOL, ...
著者Hryc, C.F, Mileykovskaya, E, Baker, M, Dowhan, W.
登録日2022-08-24
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex.
Nat Commun, 14, 2023
1BCC
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CYTOCHROME BC1 COMPLEX FROM CHICKEN
分子名称: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.-I, Kim, K.K, Hung, L.-W, Crofts, A.R, Berry, E.A, Kim, S.-H.
登録日1998-03-23
公開日1998-08-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Electron transfer by domain movement in cytochrome bc1.
Nature, 392, 1998

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