6Z9U
 
 | | Crystal structure of a TSEN15-34 heterodimer. | | Descriptor: | GLYCEROL, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen34 | | Authors: | Trowitzsch, S, Sekulovski, S. | | Deposit date: | 2020-06-04 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.10001779 Å) | | Cite: | Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
Nat Commun, 12, 2021
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8HMZ
 | | Cryo-EM structure of the human post-catalytic TSEN/pre-tRNA complex | | Descriptor: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | Authors: | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | Deposit date: | 2022-12-06 | | Release date: | 2023-04-19 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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8HMY
 | | Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex | | Descriptor: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | Authors: | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | Deposit date: | 2022-12-06 | | Release date: | 2023-04-19 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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7ZRZ
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8ISS
 | | Cryo-EM structure of wild-type human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG at 3.19 A resolution | | Descriptor: | MAGNESIUM ION, RNA (88-MER), tRNA-splicing endonuclease subunit Sen15, ... | | Authors: | Sun, Y, Zhang, Y, Yuan, L, Han, Y. | | Deposit date: | 2023-03-21 | | Release date: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Recognition and cleavage mechanism of intron-containing pre-tRNA by human TSEN endonuclease complex.
Nat Commun, 14, 2023
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7UXA
 | | Human tRNA Splicing Endonuclease Complex bound to pre-tRNA-ARG | | Descriptor: | MAGNESIUM ION, RNA (78-MER), tRNA-splicing endonuclease subunit Sen15, ... | | Authors: | Stanley, R.E, Hayne, C.K. | | Deposit date: | 2022-05-05 | | Release date: | 2023-02-08 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex.
Nat.Struct.Mol.Biol., 30, 2023
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2GW6
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