7ZRZ

Structure of the human tRNA splicing endonuclease defines substrate recognition

This is a non-PDB format compatible entry.

Summary for 7ZRZ

• Entry DOI: 10.2210/pdb7zrz/pdb
• EMDB information: 14923
• Descriptor: tRNA-splicing endonuclease subunit Sen34, tRNA-splicing endonuclease subunit Sen2, tRNA-splicing endonuclease subunit Sen54, ... (5 entities in total)
• Functional Keywords: rnp, endonuclease, trna, splicing, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 144131.42

Authors

Sekulovski, S.,Trowitzsch, S. (deposition date: 2022-05-05, release date: 2023-05-17, Last modification date: 2023-06-28)

• Primary citation: Sekulovski, S.,Susac, L.,Stelzl, L.S.,Tampe, R.,Trowitzsch, S.; Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN.; Nat.Struct.Mol.Biol., 30:834-840, 2023; PubMed: 37231152; DOI: 10.1038/s41594-023-00992-y

Experimental method

ELECTRON MICROSCOPY (3.09 Å)