7ZRZ

Structure of the human tRNA splicing endonuclease defines substrate recognition

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AP1	0000213	molecular_function	tRNA-intron endonuclease activity
AP1	0000214	cellular_component	tRNA-intron endonuclease complex
AP1	0000379	biological_process	tRNA-type intron splice site recognition and cleavage
AP1	0003676	molecular_function	nucleic acid binding
AP1	0006388	biological_process	tRNA splicing, via endonucleolytic cleavage and ligation
BP4	0000213	molecular_function	tRNA-intron endonuclease activity
BP4	0000214	cellular_component	tRNA-intron endonuclease complex
BP4	0003676	molecular_function	nucleic acid binding
BP4	0006388	biological_process	tRNA splicing, via endonucleolytic cleavage and ligation
DP1	0003676	molecular_function	nucleic acid binding
DP1	0005515	molecular_function	protein binding
DP1	0005634	cellular_component	nucleus
DP1	0005654	cellular_component	nucleoplasm
DP1	0005730	cellular_component	nucleolus
DP1	0006388	biological_process	tRNA splicing, via endonucleolytic cleavage and ligation
DP1	0006397	biological_process	mRNA processing
DP1	0008033	biological_process	tRNA processing

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
DP1	SER7
DP1	SER168
BP4	LYS416

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
CP1	SER411
BP4	SER411
BP4	SER415

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