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PDB: 9 results

3U3Z
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BU of 3u3z by Molmil
Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142
Descriptor: GLYCEROL, Histone H2A.X peptide, Microcephalin
Authors:Singh, N, Thompson, J.R, Heroux, A, Mer, G.
Deposit date:2011-10-06
Release date:2012-07-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Proc.Natl.Acad.Sci.USA, 109, 2012
3PA6
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BU of 3pa6 by Molmil
Structure of the N-terminal BRCT domain of human microcephalin (MCPH1)
Descriptor: CHLORIDE ION, Microcephalin
Authors:Singh, N, Heroux, A, Thompson, J.R, Mer, G.
Deposit date:2010-10-18
Release date:2010-12-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the N-terminal BRCT domain of human microcephalin (MCPH1)
To be Published
3KTF
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BU of 3ktf by Molmil
Structure of the N-terminal BRCT domain of human microcephalin (MCPH1).
Descriptor: CHLORIDE ION, Microcephalin
Authors:Singh, N, Heroux, A, Thompson, J.R, Mer, G.
Deposit date:2009-11-25
Release date:2009-12-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of N-terminal BRCT domain of human microcephalin (MCPH1)
To be Published
2WT8
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BU of 2wt8 by Molmil
Structure of the N-terminal BRCT domain of human microcephalin (Mcph1)
Descriptor: ACETATE ION, CHLORIDE ION, MICROCEPHALIN
Authors:Richards, M.W, Roe, S.M, Bayliss, R.
Deposit date:2009-09-14
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Pocket on the Surface of the N-Terminal Brct Domain of Mcph1 is Required to Prevent Abnormal Chromosome Condensation.
J.Mol.Biol., 395, 2010
3SHT
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BU of 3sht by Molmil
Crystal structure of human MCPH1 tandem BRCT domains
Descriptor: Microcephalin
Authors:Shao, Z.H, Li, F.D, Yan, W.
Deposit date:2011-06-17
Release date:2011-12-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
J.Struct.Biol., 177, 2012
3SHV
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BU of 3shv by Molmil
Crystal structure of human MCPH1 tandem BRCT domains-gamma H2AX complex
Descriptor: Histone H2A.x, Microcephalin
Authors:Shao, Z.H, Li, F.D, Yan, W.
Deposit date:2011-06-17
Release date:2011-12-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
J.Struct.Biol., 177, 2012
7C5D
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BU of 7c5d by Molmil
Crystal structure of TRF2 TRFH domain in complex with a MCPH1 peptide
Descriptor: GLYCEROL, Microcephalin, Telomeric repeat-binding factor 2
Authors:Xiong, X, Chen, Y.
Deposit date:2020-05-19
Release date:2020-10-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly.
Nat Commun, 11, 2020
3T1N
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BU of 3t1n by Molmil
Structure of human MICROCEPHALIN (MCPH1) TANDEM BRCT domains in complex with a CDC27 phosphopeptide
Descriptor: Cdc27 peptide, Microcephalin
Authors:Singh, N, Thompson, J.R, Mer, G.
Deposit date:2011-07-22
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex.
J.Biol.Chem., 287, 2012
3SZM
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BU of 3szm by Molmil
STRUCTURE OF HUMAN MICROCEPHALIN (MCPH1) TANDEM BRCT DOMAINS IN COMPLEX WITH A GAMMA-H2AX PHOSPHOPEPTIDE
Descriptor: Histone H2A.x, Microcephalin
Authors:Singh, N, Thompson, J.R, Mer, G.
Deposit date:2011-07-19
Release date:2011-11-30
Last modified:2012-09-19
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Proc.Natl.Acad.Sci.USA, 109, 2012

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