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3SHT

Crystal structure of human MCPH1 tandem BRCT domains

Summary for 3SHT
Entry DOI10.2210/pdb3sht/pdb
Related3SHV
DescriptorMicrocephalin (2 entities in total)
Functional Keywordstandem brct domains, cell cycle
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton, microtubule organizing center, centrosome : Q8NEM0
Total number of polymer chains3
Total formula weight68617.85
Authors
Shao, Z.H.,Li, F.D.,Yan, W. (deposition date: 2011-06-17, release date: 2011-12-28, Last modification date: 2023-11-01)
Primary citationShao, Z.H.,Li, F.D.,Sy, S.M.-H.,Yan, W.,Zhang, Z.,Gong, D.,Wen, B.,Huen, M.S.Y.,Gong, Q.,Wu, J.,Shi, Y.
Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
J.Struct.Biol., 177:459-468, 2012
Cited by
PubMed: 22154951
DOI: 10.1016/j.jsb.2011.11.022
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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