3SHT

Crystal structure of human MCPH1 tandem BRCT domains

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Microcephalin	polymer	206	22872.6	3	UniProt (Q8NEM0)	Homo sapiens (human)
2	D, E, F (A, B, C)	water	water		18.0	447	Chemie (HOH)

Sequence modifications

A, B, C: 639 - 835 (UniProt: Q8NEM0)

PDB	External Database	Details
Met 630	-	expression tag
Gly 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag
His 635	-	expression tag
His 636	-	expression tag
His 637	-	expression tag
Met 638	-	expression tag
Ala 761	Val 761	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	68617.8
All*	Total formula weight	68617.8

*Water molecules are not included.