3T1N
Structure of human MICROCEPHALIN (MCPH1) TANDEM BRCT domains in complex with a CDC27 phosphopeptide
Summary for 3T1N
Entry DOI | 10.2210/pdb3t1n/pdb |
Descriptor | Microcephalin, Cdc27 peptide (3 entities in total) |
Functional Keywords | tandem brct domains, cell cycle regulation, dna repair, mitosis, phosphorylation, cell cycle-peptide complex, cell cycle/peptide |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, centrosome: Q8NEM0 |
Total number of polymer chains | 4 |
Total formula weight | 45052.00 |
Authors | Singh, N.,Thompson, J.R.,Mer, G. (deposition date: 2011-07-22, release date: 2011-11-30, Last modification date: 2023-09-13) |
Primary citation | Singh, N.,Wiltshire, T.D.,Thompson, J.R.,Mer, G.,Couch, F.J. Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex. J.Biol.Chem., 287:2854-2862, 2012 Cited by PubMed: 22139841DOI: 10.1074/jbc.M111.307868 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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