1IW7
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3EQL
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![BU of 3eql by Molmil](/molmil-images/mine/3eql) | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I. | Deposit date: | 2008-09-30 | Release date: | 2008-10-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Transcription inactivation through local refolding of the RNA polymerase structure. Nature, 457, 2009
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1SMY
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![BU of 1smy by Molmil](/molmil-images/mine/1smy) | Structural basis for transcription regulation by alarmone ppGpp | Descriptor: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | Authors: | Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-03-10 | Release date: | 2004-05-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for transcription regulation by alarmone ppGpp Cell(Cambridge,Mass.), 117, 2004
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5TMC
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![BU of 5tmc by Molmil](/molmil-images/mine/5tmc) | Re-refinement of Thermus thermopiles DNA-directed RNA polymerase structure | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Wang, J. | Deposit date: | 2016-10-12 | Release date: | 2016-11-23 | Last modified: | 2019-02-20 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | On the validation of crystallographic symmetry and the quality of structures. Protein Sci., 24, 2015
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6OW3
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6P71
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6CUU
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![BU of 6cuu by Molmil](/molmil-images/mine/6cuu) | Thermus thermophiles RNA polymerase in complex with promoter DNA and antibiotic Kanglemycin A | Descriptor: | DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*A)-3'), DNA (5'-D(P*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Molodtsov, V, Murakami, K.S. | Deposit date: | 2018-03-26 | Release date: | 2018-07-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.994 Å) | Cite: | Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. Mol. Cell, 72, 2018
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6OVY
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5TMF
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![BU of 5tmf by Molmil](/molmil-images/mine/5tmf) | Re-refinement of thermus thermophilus RNA polymerase | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Wang, J. | Deposit date: | 2016-10-12 | Release date: | 2016-11-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | On the validation of crystallographic symmetry and the quality of structures. Protein Sci., 24, 2015
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5D4D
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6WOY
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6OY7
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6P70
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![BU of 6p70 by Molmil](/molmil-images/mine/6p70) | X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex | Descriptor: | DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Shin, Y, Murakami, K.S. | Deposit date: | 2019-06-04 | Release date: | 2019-06-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
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5D4E
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6OY6
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6OY5
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![BU of 6oy5 by Molmil](/molmil-images/mine/6oy5) | |
6WOX
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5X21
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![BU of 5x21 by Molmil](/molmil-images/mine/5x21) | Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) | Descriptor: | (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Zhang, Y, Ebright, R. | Deposit date: | 2017-01-29 | Release date: | 2017-07-05 | Last modified: | 2022-10-12 | Method: | X-RAY DIFFRACTION (3.323 Å) | Cite: | Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
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5X22
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