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PDB: 23 results
2P26
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BU of 2p26 by Molmil
Structure of the PHE2 and PHE3 fragments of the integrin beta2 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Shi, M, Foo, S.Y, Tan, S.M, Mitchell, E.P, Law, S.K.A, Lescar, J.
Deposit date:2007-03-06
Release date:2007-08-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins
J.Biol.Chem., 282, 2007
5E6X
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BU of 5e6x by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Springer, T.A, Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5E6V
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BU of 5e6v by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Sen, M, Springer, T.A.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
1YUK
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BU of 1yuk by Molmil
The crystal structure of the PSI/Hybrid domain/ I-EGF1 segment from the human integrin beta2 at 1.8 resolution
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, Integrin beta-2 A chain, Integrin beta-2 B chain
Authors:Shi, M, Sundramurthy, K, Liu, B, Tan, S.M, Law, S.K, Lescar, J.
Deposit date:2005-02-14
Release date:2005-07-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin {beta}2 Subunit at 1.8-A Resolution
J.Biol.Chem., 280, 2005
5E6S
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BU of 5e6s by Molmil
Structures of leukocyte integrin aLB2: The aI domain, the headpiece, and the pocket for the internal ligand
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ...
Authors:Springer, T.A, Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
2P28
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BU of 2p28 by Molmil
Structure of the PHE2 and PHE3 fragments of the integrin beta2 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Shi, M, Foo, S.Y, Tan, S.M, Mitchell, E.P, Law, S.K.A, Lescar, J.
Deposit date:2007-03-07
Release date:2007-08-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins
J.Biol.Chem., 282, 2007
5E6W
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BU of 5e6w by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
Authors:Springer, T.A, Sen, M.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
2JF1
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BU of 2jf1 by Molmil
CRYSTAL STRUCTURE OF THE FILAMIN A REPEAT 21 COMPLEXED WITH THE INTEGRIN BETA2 CYTOPLASMIC TAIL PEPTIDE
Descriptor: FILAMIN-A, GLYCEROL, INTEGRIN BETA-2 SUBUNIT
Authors:Kiema, T, Ylanne, J.
Deposit date:2007-01-25
Release date:2008-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.
Blood, 112, 2008
5E6U
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BU of 5e6u by Molmil
Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Sen, M, Springer, T.A.
Deposit date:2015-10-10
Release date:2016-04-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
2V7D
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BU of 2v7d by Molmil
14-3-3 protein zeta in complex with Thr758 phosphorylated integrin beta2 peptide
Descriptor: 14-3-3 PROTEIN ZETA/DELTA, INTEGRIN BETA CHAIN, BETA 2 VARIANT
Authors:Takala, H, Ylanne, J.
Deposit date:2007-07-30
Release date:2008-06-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.
Blood, 112, 2008
7USL
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BU of 7usl by Molmil
Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-04-25
Release date:2022-08-17
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
7USM
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BU of 7usm by Molmil
Integrin alphaM/beta2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-04-25
Release date:2022-08-17
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
4NEH
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BU of 4neh by Molmil
An internal ligand-bound, metastable state of a leukocyte integrin, aXb2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Sen, M, Yuki, K, Springer, T.A.
Deposit date:2013-10-29
Release date:2014-01-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7505 Å)
Cite:An internal ligand-bound, metastable state of a leukocyte integrin, alpha X beta 2.
J.Cell Biol., 203, 2013
5E6R
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BU of 5e6r by Molmil
Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ...
Authors:Sen, M, Springer, T.A.
Deposit date:2015-10-10
Release date:2016-03-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
4NEN
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BU of 4nen by Molmil
An internal ligand-bound, metastable state of a leukocyte integrin, aXb2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Sen, M, Yuki, K, Springer, T.A.
Deposit date:2013-10-29
Release date:2014-01-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9012 Å)
Cite:An internal ligand-bound, metastable state of a leukocyte integrin, alpha X beta 2.
J.Cell Biol., 203, 2013
7P2D
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BU of 7p2d by Molmil
Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Jensen, R.K, Andersen, G.R.
Deposit date:2021-07-05
Release date:2022-05-04
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.
J.Biol.Chem., 298, 2022
5ES4
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BU of 5es4 by Molmil
RE-REFINEMENT OF INTEGRIN ALPHAXBETA2 ECTODOMAIN IN THE CLOSED/BENT CONFORMATION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Sen, M, Springer, T.A.
Deposit date:2015-11-16
Release date:2016-03-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
3K6S
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BU of 3k6s by Molmil
Structure of integrin alphaXbeta2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
Deposit date:2009-10-09
Release date:2010-01-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
3K72
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BU of 3k72 by Molmil
Structure of integrin alphaX beta2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
Deposit date:2009-10-11
Release date:2010-01-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
3K71
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BU of 3k71 by Molmil
Structure of integrin alphaX beta2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
Deposit date:2009-10-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
5XR1
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BU of 5xr1 by Molmil
Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2
Descriptor: C-terminal peptide of Integrin beta-2,Filamin-A IG21 domain
Authors:Chatterjee, D, Lu, L.Z, Bhattacharjya, S.
Deposit date:2017-06-07
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2
To Be Published
5ZAZ
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BU of 5zaz by Molmil
Solution structure of integrin b2 monomer tranmembrane domain in bicelle
Descriptor: Integrin beta-2
Authors:Li, H, Guo, J, Xu, C.
Deposit date:2018-02-09
Release date:2018-10-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Intramembrane ionic protein-lipid interaction regulates integrin structure and function.
PLoS Biol., 16, 2018
1L3Y
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BU of 1l3y by Molmil
INTEGRIN EGF-LIKE MODULE 3 FROM THE BETA-2 SUBUNIT
Descriptor: Integrin beta-2:CYSTEINE-RICH MODULE 3
Authors:Beglova, N, Blacklow, S.C, Takagi, J, Springer, T.A.
Deposit date:2002-03-03
Release date:2002-04-01
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation.
Nat.Struct.Biol., 9, 2002

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