7P2D

Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody

Summary for 7P2D

• Entry DOI: 10.2210/pdb7p2d/pdb
• Related: 7NP9
• Descriptor: Isoform 2 of Integrin alpha-M, Integrin beta, hCD11bNb1 nanobody, ... (6 entities in total)
• Functional Keywords: integrin receptor, complement, adhesion, phagocytosis, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 152830.30

Authors

Jensen, R.K.,Andersen, G.R. (deposition date: 2021-07-05, release date: 2022-05-04, Last modification date: 2024-01-31)

• Primary citation: Jensen, R.K.,Pedersen, H.,Lorentzen, J.,Laursen, N.S.,Vorup-Jensen, T.,Andersen, G.R.; Structural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.; J.Biol.Chem., 298:102168-102168, 2022; PubMed: 35738398; DOI: 10.1016/j.jbc.2022.102168

Experimental method

X-RAY DIFFRACTION (3.2 Å)