7P2D
Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2 of Integrin alpha-M | polymer | 763 | 84010.9 | 1 | UniProt (P11215) Pfam (PF00092) Pfam (PF01839) Pfam (PF08441) | Homo sapiens (Human) | CD11 antigen-like family member B,CR-3 alpha chain,Cell surface glycoprotein MAC-1 subunit alpha,Leukocyte adhesion receptor MO1,Neutrophil adherence receptor |
| 2 | B (B) | Integrin beta | polymer | 473 | 52692.6 | 1 | UniProt (A0A494C0X7) Pfam (PF17205) Pfam (PF00362) UniProt (by SIFTS) (P05107) | Homo sapiens (Human) | |
| 3 | C (C) | hCD11bNb1 nanobody | polymer | 129 | 14127.8 | 1 | Lama glama (Llama) | ||
| 4 | D, E, F, G (D, E, F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 5 | H, I (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | J (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 1 - 756 (UniProt: P11215)
B: 1 - 460 (UniProt: A0A494C0X7)
| PDB | External Database | Details |
|---|---|---|
| Arg 224 | Asn 240 | conflict |
| Arg 681 | Asn 697 | conflict |
| Thr 755 | Cys 771 | conflict |
| Gly 757 | - | expression tag |
| Leu 758 | - | expression tag |
| Glu 759 | - | expression tag |
| Val 760 | - | expression tag |
| Leu 761 | - | expression tag |
| Phe 762 | - | expression tag |
| Gln 763 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Lys 461 | - | expression tag |
| Asn 462 | - | expression tag |
| Cys 463 | - | expression tag |
| Glu 464 | - | expression tag |
| Pro 465 | - | expression tag |
| Ala 466 | - | expression tag |
| Ala 467 | - | expression tag |
| Leu 468 | - | expression tag |
| Gln 469 | - | expression tag |
| Thr 470 | - | expression tag |
| Leu 471 | - | expression tag |
| Phe 472 | - | expression tag |
| Gln 473 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 150831.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 301.4 | |
| All* | Total formula weight | 152830.3 |
