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PDB: 14 results

4YUD
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BU of 4yud by Molmil
Crystal structure of a RNA binding motif protein 39 (RBM39) from Homo sapiens at 1.28 A resolution
Descriptor: RNA-binding protein 39
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2015-03-18
Release date:2015-04-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal structure of a RNA binding motif protein 39 (RBM39) from Homo sapiens at 1.28 A resolution
To be published
4OZ1
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BU of 4oz1 by Molmil
Crystal structure of human CAPERalpha UHM bound to SF3b155 ULM5
Descriptor: CHLORIDE ION, LYSINE, POTASSIUM ION, ...
Authors:Loerch, S, Kielkopf, C.L.
Deposit date:2014-02-13
Release date:2014-05-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Cancer-relevant splicing factor CAPER alpha engages the essential splicing factor SF3b155 in a specific ternary complex.
J.Biol.Chem., 289, 2014
4OZ0
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Crystal structure of human CAPERalpha U2AF homology motif (apo-state)
Descriptor: CHLORIDE ION, RNA-binding protein 39
Authors:Loerch, S, Kielkopf, C.L.
Deposit date:2014-02-13
Release date:2014-05-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cancer-relevant splicing factor CAPER alpha engages the essential splicing factor SF3b155 in a specific ternary complex.
J.Biol.Chem., 289, 2014
6UD7
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Crystal structure of full-length human DCAF15-DDB1(deltaBPB)-DDA1-RBM39 in complex with indisulam
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1,DNA damage-binding protein 1, ...
Authors:Bussiere, D.E, Shu, W, Xie, L, Knapp, M.
Deposit date:2019-09-18
Release date:2019-12-18
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
6UE5
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BU of 6ue5 by Molmil
Crystal structure of full-length human DCAF15-DDB1-deltaPBP-DDA1-RBM39 in complex with 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
Descriptor: 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ...
Authors:Knapp, M.S, Shu, W, Xie, L, Bussiere, D.E.
Deposit date:2019-09-20
Release date:2019-12-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
4OO6
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BU of 4oo6 by Molmil
Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)
Descriptor: RNA-binding protein 39, Transportin-1
Authors:Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
Deposit date:2014-01-30
Release date:2014-02-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1)
to be published
6Q0V
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BU of 6q0v by Molmil
Structure of DDB1-DDA1-DCAF15 complex bound to tasisulam and RBM39
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ...
Authors:Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S.
Deposit date:2019-08-02
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.
Nat.Chem.Biol., 16, 2020
6PAI
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BU of 6pai by Molmil
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and sulfonamide E7820
Descriptor: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DDB1- and CUL4-associated factor 15, ...
Authors:Volkov, O.A, Du, X.
Deposit date:2019-06-11
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820.
Structure, 27, 2019
6Q0R
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BU of 6q0r by Molmil
Structure of DDB1-DDA1-DCAF15 complex bound to E7820 and RBM39
Descriptor: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ...
Authors:Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S.
Deposit date:2019-08-02
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.
Nat.Chem.Biol., 16, 2020
6Q0W
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BU of 6q0w by Molmil
Structure of DDB1-DDA1-DCAF15 complex bound to Indisulam and RBM39
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ...
Authors:Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S.
Deposit date:2019-08-02
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.
Nat.Chem.Biol., 16, 2020
6SJ7
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BU of 6sj7 by Molmil
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and Indisulam
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ...
Authors:Srinivas, H.
Deposit date:2019-08-12
Release date:2019-12-18
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
7Q33
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BU of 7q33 by Molmil
Solution structure of RBM39 RRM2 bound to 5'-AGCUUUG-3
Descriptor: RNA (5'-R(*AP*GP*CP*UP*UP*UP*G)-3'), RNA-binding protein 39
Authors:Campagne, S, Allain, F.H.
Deposit date:2021-10-26
Release date:2023-02-08
Last modified:2023-09-20
Method:SOLUTION NMR
Cite:Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Nat Commun, 14, 2023
2JRS
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BU of 2jrs by Molmil
Solution NMR Structure of CAPER RRM2 Domain. Northeast Structural Genomics Target HR4730A
Descriptor: RNA-binding protein 39
Authors:Rossi, P, Zhao, L, Nwosu, C, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-28
Release date:2007-09-04
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution NMR Structure of CAPER RRM2 Domain.
To be Published
2MHN
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BU of 2mhn by Molmil
NMR structure of the first RRM domain of the protein RBM39 from Homo sapiens
Descriptor: RNA-binding protein 39
Authors:Serrano, P, Geralt, M, Dutta, S.K, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-12-02
Release date:2014-01-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of the first RRM domain of the protein RBM39 from Homo sapiens
To be Published

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PDB entries from 2024-10-16

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