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PDB: 14 results

6W1S
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BU of 6w1s by Molmil
Atomic model of the mammalian Mediator complex
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Zhao, H, Young, N, Asturias, F.
Deposit date:2020-03-04
Release date:2021-03-10
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
Cell, 178, 2019
8GXQ
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PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y.
Deposit date:2022-09-21
Release date:2022-11-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (5.04 Å)
Cite:Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8GXS
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BU of 8gxs by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X.
Deposit date:2022-09-21
Release date:2022-11-02
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
7LBM
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BU of 7lbm by Molmil
Structure of the human Mediator-bound transcription pre-initiation complex
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abdella, R, Talyzina, A, He, Y.
Deposit date:2021-01-08
Release date:2021-03-24
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structure of the human Mediator-bound transcription preinitiation complex.
Science, 372, 2021
7NVR
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BU of 7nvr by Molmil
Human Mediator with RNA Polymerase II Pre-initiation complex
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Rengachari, S, Schilbach, S, Aibara, S, Cramer, P.
Deposit date:2021-03-15
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7EMF
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BU of 7emf by Molmil
Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation
Descriptor: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ...
Authors:Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y.
Deposit date:2021-04-13
Release date:2021-05-05
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENJ
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BU of 7enj by Molmil
Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B)
Descriptor: Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ...
Authors:Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y.
Deposit date:2021-04-17
Release date:2021-05-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENA
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BU of 7ena by Molmil
TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENC
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BU of 7enc by Molmil
TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
8T1L
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BU of 8t1l by Molmil
Atomic model of the mammalian mouse Mediator complex with CKM module
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Zhao, H, Asturias, F.
Deposit date:2023-06-02
Release date:2024-07-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.83 Å)
Cite:A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers.
To Be Published
8T1I
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BU of 8t1i by Molmil
Atomic model of the mammalian Mediator complex with MED26 subunit
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Zhao, H, Asturias, F.
Deposit date:2023-06-02
Release date:2024-06-12
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.68 Å)
Cite:An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Mol.Cell, 84, 2024
8T9D
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BU of 8t9d by Molmil
CryoEM structure of TR-TRAP
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Zhao, H, Asturias, F.
Deposit date:2023-06-23
Release date:2024-07-03
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.66 Å)
Cite:An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Mol.Cell, 84, 2024
8TRH
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BU of 8trh by Molmil
The IDRc bound human core Mediator complex
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ...
Authors:Chen, S.F, Chao, T.C, Kim, H.J, Tang, H.C, Khadka, S, Li, T, Murakami, K, Boyer, T.G, Tsai, K.L.
Deposit date:2023-08-09
Release date:2024-10-09
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module.
Mol.Cell, 84, 2024
8TQW
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BU of 8tqw by Molmil
Structure of human transcriptional Mediator complex
Descriptor: Cyclin-C, Cyclin-dependent kinase 8, Mediator of RNA polymerase II transcription subunit 1, ...
Authors:Chen, S.F, Chao, T.C, Kim, H.J, Tang, H.C, Khadka, S, Li, T, Murakami, K, Boyer, T.G, Tsai, K.L.
Deposit date:2023-08-08
Release date:2024-10-09
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module.
Mol.Cell, 84, 2024

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PDB entries from 2024-11-06

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