7ENC

TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)

This is a non-PDB format compatible entry.

Summary for 7ENC

• Entry DOI: 10.2210/pdb7enc/pdb
• EMDB information: 31207
• Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 14, ... (73 entities in total)
• Functional Keywords: mediator, preinitiation complex, transcription initiation, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 76
• Total formula weight: 3882036.83

Authors

Chen, X.,Qi, Y.,Wang, X.,Wu, Z.,Yin, X.,Li, J.,Liu, W.,Xu, Y. (deposition date: 2021-04-16, release date: 2021-05-26, Last modification date: 2021-06-16)

• Primary citation: Chen, X.,Yin, X.,Li, J.,Wu, Z.,Qi, Y.,Wang, X.,Liu, W.,Xu, Y.; Structures of the human Mediator and Mediator-bound preinitiation complex.; Science, 372:-, 2021; PubMed: 33958484; DOI: 10.1126/science.abg0635

Experimental method

ELECTRON MICROSCOPY (4.13 Å)