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7ENC

TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
00000082biological_processG1/S transition of mitotic cell cycle
00000307cellular_componentcyclin-dependent protein kinase holoenzyme complex
00000439cellular_componenttranscription factor TFIIH core complex
00005515molecular_functionprotein binding
00005634cellular_componentnucleus
00005654cellular_componentnucleoplasm
00005675cellular_componenttranscription factor TFIIH holo complex
00006281biological_processDNA repair
00006289biological_processnucleotide-excision repair
00006355biological_processregulation of DNA-templated transcription
00006357biological_processregulation of transcription by RNA polymerase II
00006367biological_processtranscription initiation at RNA polymerase II promoter
00007512biological_processadult heart development
00008270molecular_functionzinc ion binding
00021591biological_processventricular system development
00043066biological_processnegative regulation of apoptotic process
00045737biological_processpositive regulation of cyclin-dependent protein serine/threonine kinase activity
00046872molecular_functionmetal ion binding
00048661biological_processpositive regulation of smooth muscle cell proliferation
00051592biological_processresponse to calcium ion
00061575molecular_functioncyclin-dependent protein serine/threonine kinase activator activity
00070516cellular_componentCAK-ERCC2 complex
00070985cellular_componenttranscription factor TFIIK complex
02000045biological_processregulation of G1/S transition of mitotic cell cycle
10000079biological_processregulation of cyclin-dependent protein serine/threonine kinase activity
10000439cellular_componenttranscription factor TFIIH core complex
10003682molecular_functionchromatin binding
10005515molecular_functionprotein binding
10005634cellular_componentnucleus
10005654cellular_componentnucleoplasm
10005675cellular_componenttranscription factor TFIIH holo complex
10006281biological_processDNA repair
10006289biological_processnucleotide-excision repair
10006351biological_processDNA-templated transcription
10006360biological_processtranscription by RNA polymerase I
10006366biological_processtranscription by RNA polymerase II
10006367biological_processtranscription initiation at RNA polymerase II promoter
10009755biological_processhormone-mediated signaling pathway
10045893biological_processpositive regulation of DNA-templated transcription
10046966molecular_functionnuclear thyroid hormone receptor binding
20000438cellular_componentcore TFIIH complex portion of holo TFIIH complex
20000439cellular_componenttranscription factor TFIIH core complex
20002031biological_processG protein-coupled receptor internalization
20005515molecular_functionprotein binding
20005634cellular_componentnucleus
20005654cellular_componentnucleoplasm
20005669cellular_componenttranscription factor TFIID complex
20005675cellular_componenttranscription factor TFIIH holo complex
20006281biological_processDNA repair
20006289biological_processnucleotide-excision repair
20006351biological_processDNA-templated transcription
20006357biological_processregulation of transcription by RNA polymerase II
20006366biological_processtranscription by RNA polymerase II
20006367biological_processtranscription initiation at RNA polymerase II promoter
20008270molecular_functionzinc ion binding
20009411biological_processresponse to UV
20016251molecular_functionRNA polymerase II general transcription initiation factor activity
20016607cellular_componentnuclear speck
20046872molecular_functionmetal ion binding
30000438cellular_componentcore TFIIH complex portion of holo TFIIH complex
30000439cellular_componenttranscription factor TFIIH core complex
30005515molecular_functionprotein binding
30005634cellular_componentnucleus
30005654cellular_componentnucleoplasm
30005669cellular_componenttranscription factor TFIID complex
30005675cellular_componenttranscription factor TFIIH holo complex
30006281biological_processDNA repair
30006289biological_processnucleotide-excision repair
30006355biological_processregulation of DNA-templated transcription
30006366biological_processtranscription by RNA polymerase II
30016251molecular_functionRNA polymerase II general transcription initiation factor activity
30046872molecular_functionmetal ion binding
30097550cellular_componenttranscription preinitiation complex
40000438cellular_componentcore TFIIH complex portion of holo TFIIH complex
40000439cellular_componenttranscription factor TFIIH core complex
40001671molecular_functionATPase activator activity
40003690molecular_functiondouble-stranded DNA binding
40005515molecular_functionprotein binding
40005634cellular_componentnucleus
40005654cellular_componentnucleoplasm
40005669cellular_componenttranscription factor TFIID complex
40005675cellular_componenttranscription factor TFIIH holo complex
40006281biological_processDNA repair
40006289biological_processnucleotide-excision repair
40006366biological_processtranscription by RNA polymerase II
40016251molecular_functionRNA polymerase II general transcription initiation factor activity
40016607cellular_componentnuclear speck
50000439cellular_componenttranscription factor TFIIH core complex
50000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
50005515molecular_functionprotein binding
50005634cellular_componentnucleus
50005654cellular_componentnucleoplasm
50005669cellular_componenttranscription factor TFIID complex
50005675cellular_componenttranscription factor TFIIH holo complex
50005730cellular_componentnucleolus
50005737cellular_componentcytoplasm
50006281biological_processDNA repair
50006289biological_processnucleotide-excision repair
50006294biological_processnucleotide-excision repair, preincision complex assembly
50006362biological_processtranscription elongation by RNA polymerase I
50006366biological_processtranscription by RNA polymerase II
50006367biological_processtranscription initiation at RNA polymerase II promoter
50071480biological_processcellular response to gamma radiation
60000112cellular_componentnucleotide-excision repair factor 3 complex
60000439cellular_componenttranscription factor TFIIH core complex
60000717biological_processnucleotide-excision repair, DNA duplex unwinding
60001666biological_processresponse to hypoxia
60003677molecular_functionDNA binding
60003678molecular_functionDNA helicase activity
60003684molecular_functiondamaged DNA binding
60004386molecular_functionhelicase activity
60005515molecular_functionprotein binding
60005524molecular_functionATP binding
60005634cellular_componentnucleus
60005654cellular_componentnucleoplasm
60005669cellular_componenttranscription factor TFIID complex
60005675cellular_componenttranscription factor TFIIH holo complex
60006265biological_processDNA topological change
60006281biological_processDNA repair
60006283biological_processtranscription-coupled nucleotide-excision repair
60006289biological_processnucleotide-excision repair
60006366biological_processtranscription by RNA polymerase II
60006367biological_processtranscription initiation at RNA polymerase II promoter
60006368biological_processtranscription elongation by RNA polymerase II
60006915biological_processapoptotic process
60006979biological_processresponse to oxidative stress
60008104biological_processprotein localization
60009411biological_processresponse to UV
60009650biological_processUV protection
60016787molecular_functionhydrolase activity
60016853molecular_functionisomerase activity
60016887molecular_functionATP hydrolysis activity
60035315biological_processhair cell differentiation
60043065biological_processpositive regulation of apoptotic process
60043138molecular_function3'-5' DNA helicase activity
60048568biological_processembryonic organ development
60097550cellular_componenttranscription preinitiation complex
61901990biological_processregulation of mitotic cell cycle phase transition
61990841molecular_functionpromoter-specific chromatin binding
70000439cellular_componenttranscription factor TFIIH core complex
70000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
70001666biological_processresponse to hypoxia
70001701biological_processin utero embryonic development
70003676molecular_functionnucleic acid binding
70003677molecular_functionDNA binding
70003678molecular_functionDNA helicase activity
70003684molecular_functiondamaged DNA binding
70004386molecular_functionhelicase activity
70005515molecular_functionprotein binding
70005524molecular_functionATP binding
70005634cellular_componentnucleus
70005654cellular_componentnucleoplasm
70005669cellular_componenttranscription factor TFIID complex
70005675cellular_componenttranscription factor TFIIH holo complex
70005737cellular_componentcytoplasm
70005819cellular_componentspindle
70005829cellular_componentcytosol
70005856cellular_componentcytoskeleton
70006139biological_processnucleobase-containing compound metabolic process
70006259biological_processDNA metabolic process
70006281biological_processDNA repair
70006283biological_processtranscription-coupled nucleotide-excision repair
70006289biological_processnucleotide-excision repair
70006357biological_processregulation of transcription by RNA polymerase II
70006362biological_processtranscription elongation by RNA polymerase I
70006366biological_processtranscription by RNA polymerase II
70006367biological_processtranscription initiation at RNA polymerase II promoter
70006915biological_processapoptotic process
70006974biological_processDNA damage response
70006979biological_processresponse to oxidative stress
70007059biological_processchromosome segregation
70008340biological_processdetermination of adult lifespan
70009411biological_processresponse to UV
70009650biological_processUV protection
70009791biological_processpost-embryonic development
70016787molecular_functionhydrolase activity
70016818molecular_functionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
70016853molecular_functionisomerase activity
70016887molecular_functionATP hydrolysis activity
70021510biological_processspinal cord development
70022405biological_processhair cycle process
70030198biological_processextracellular matrix organization
70030282biological_processbone mineralization
70030674molecular_functionprotein-macromolecule adaptor activity
70032289biological_processcentral nervous system myelin formation
70032508biological_processDNA duplex unwinding
70035264biological_processmulticellular organism growth
70035315biological_processhair cell differentiation
70040016biological_processembryonic cleavage
70042274biological_processribosomal small subunit biogenesis
70043139molecular_function5'-3' DNA helicase activity
70043249biological_processerythrocyte maturation
70043588biological_processskin development
70045951biological_processpositive regulation of mitotic recombination
70046872molecular_functionmetal ion binding
70048009biological_processinsulin-like growth factor receptor signaling pathway
70048568biological_processembryonic organ development
70048820biological_processhair follicle maturation
70051539molecular_function4 iron, 4 sulfur cluster binding
70060218biological_processhematopoietic stem cell differentiation
70070516cellular_componentCAK-ERCC2 complex
70071425biological_processhematopoietic stem cell proliferation
70071817cellular_componentMMXD complex
70072332biological_processintrinsic apoptotic signaling pathway by p53 class mediator
71901990biological_processregulation of mitotic cell cycle phase transition
80000307cellular_componentcyclin-dependent protein kinase holoenzyme complex
80000439cellular_componenttranscription factor TFIIH core complex
80001650cellular_componentfibrillar center
80001673cellular_componentmale germ cell nucleus
80004672molecular_functionprotein kinase activity
80004674molecular_functionprotein serine/threonine kinase activity
80004693molecular_functioncyclin-dependent protein serine/threonine kinase activity
80005515molecular_functionprotein binding
80005524molecular_functionATP binding
80005634cellular_componentnucleus
80005654cellular_componentnucleoplasm
80005675cellular_componenttranscription factor TFIIH holo complex
80005737cellular_componentcytoplasm
80005829cellular_componentcytosol
80005886cellular_componentplasma membrane
80006281biological_processDNA repair
80006366biological_processtranscription by RNA polymerase II
80006367biological_processtranscription initiation at RNA polymerase II promoter
80006468biological_processprotein phosphorylation
80008094molecular_functionATP-dependent activity, acting on DNA
80008353molecular_functionRNA polymerase II CTD heptapeptide repeat kinase activity
80016301molecular_functionkinase activity
80016310biological_processphosphorylation
80042795biological_processsnRNA transcription by RNA polymerase II
80045944biological_processpositive regulation of transcription by RNA polymerase II
80048471cellular_componentperinuclear region of cytoplasm
80050821biological_processprotein stabilization
80051301biological_processcell division
80051726biological_processregulation of cell cycle
80070516cellular_componentCAK-ERCC2 complex
80070985cellular_componenttranscription factor TFIIK complex
80106310molecular_functionprotein serine kinase activity
82000045biological_processregulation of G1/S transition of mitotic cell cycle
90000307cellular_componentcyclin-dependent protein kinase holoenzyme complex
90000439cellular_componenttranscription factor TFIIH core complex
90005515molecular_functionprotein binding
90005634cellular_componentnucleus
90005654cellular_componentnucleoplasm
90005675cellular_componenttranscription factor TFIIH holo complex
90006351biological_processDNA-templated transcription
90006357biological_processregulation of transcription by RNA polymerase II
90006367biological_processtranscription initiation at RNA polymerase II promoter
90016251molecular_functionRNA polymerase II general transcription initiation factor activity
90016538molecular_functioncyclin-dependent protein serine/threonine kinase regulator activity
90050821biological_processprotein stabilization
90070516cellular_componentCAK-ERCC2 complex
90070985cellular_componenttranscription factor TFIIK complex
92000045biological_processregulation of G1/S transition of mitotic cell cycle
BA0000776cellular_componentkinetochore
BA0000793cellular_componentcondensed chromosome
BA0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
BA0000993molecular_functionRNA polymerase II complex binding
BA0001174biological_processtranscriptional start site selection at RNA polymerase II promoter
BA0003677molecular_functionDNA binding
BA0004402molecular_functionhistone acetyltransferase activity
BA0005515molecular_functionprotein binding
BA0005634cellular_componentnucleus
BA0005654cellular_componentnucleoplasm
BA0005669cellular_componenttranscription factor TFIID complex
BA0005694cellular_componentchromosome
BA0006338biological_processchromatin remodeling
BA0006352biological_processDNA-templated transcription initiation
BA0006366biological_processtranscription by RNA polymerase II
BA0006367biological_processtranscription initiation at RNA polymerase II promoter
BA0006473biological_processprotein acetylation
BA0008270molecular_functionzinc ion binding
BA0010467biological_processgene expression
BA0016251molecular_functionRNA polymerase II general transcription initiation factor activity
BA0016407molecular_functionacetyltransferase activity
BA0016604cellular_componentnuclear body
BA0016746molecular_functionacyltransferase activity
BA0017025molecular_functionTBP-class protein binding
BA0019083biological_processviral transcription
BA0032153cellular_componentcell division site
BA0032993cellular_componentprotein-DNA complex
BA0042585cellular_componentgerminal vesicle
BA0046872molecular_functionmetal ion binding
BA0046966molecular_functionnuclear thyroid hormone receptor binding
BA0051123biological_processRNA polymerase II preinitiation complex assembly
BA0051177biological_processmeiotic sister chromatid cohesion
BA0051225biological_processspindle assembly
BA0051276biological_processchromosome organization
BA0061733molecular_functionpeptide-lysine-N-acetyltransferase activity
BA0070897biological_processtranscription preinitiation complex assembly
BA0090575cellular_componentRNA polymerase II transcription regulator complex
BA0097550cellular_componenttranscription preinitiation complex
BA0140297molecular_functionDNA-binding transcription factor binding
BA1904798biological_processpositive regulation of core promoter binding
BA1990114biological_processRNA polymerase II core complex assembly
BA1990841molecular_functionpromoter-specific chromatin binding
DA0000122biological_processnegative regulation of transcription by RNA polymerase II
DA0000209biological_processprotein polyubiquitination
DA0000785cellular_componentchromatin
DA0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
DA0001091molecular_functionRNA polymerase II general transcription initiation factor binding
DA0001181molecular_functionRNA polymerase I general transcription initiation factor activity
DA0002039molecular_functionp53 binding
DA0003677molecular_functionDNA binding
DA0004402molecular_functionhistone acetyltransferase activity
DA0004672molecular_functionprotein kinase activity
DA0004674molecular_functionprotein serine/threonine kinase activity
DA0005515molecular_functionprotein binding
DA0005524molecular_functionATP binding
DA0005634cellular_componentnucleus
DA0005654cellular_componentnucleoplasm
DA0005667cellular_componenttranscription regulator complex
DA0005669cellular_componenttranscription factor TFIID complex
DA0005730cellular_componentnucleolus
DA0006325biological_processchromatin organization
DA0006338biological_processchromatin remodeling
DA0006352biological_processDNA-templated transcription initiation
DA0006361biological_processtranscription initiation at RNA polymerase I promoter
DA0006366biological_processtranscription by RNA polymerase II
DA0006367biological_processtranscription initiation at RNA polymerase II promoter
DA0006468biological_processprotein phosphorylation
DA0006511biological_processubiquitin-dependent protein catabolic process
DA0006974biological_processDNA damage response
DA0010629biological_processnegative regulation of gene expression
DA0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DA0016301molecular_functionkinase activity
DA0016310biological_processphosphorylation
DA0016746molecular_functionacyltransferase activity
DA0016922molecular_functionnuclear receptor binding
DA0017025molecular_functionTBP-class protein binding
DA0018105biological_processpeptidyl-serine phosphorylation
DA0018107biological_processpeptidyl-threonine phosphorylation
DA0030901biological_processmidbrain development
DA0032092biological_processpositive regulation of protein binding
DA0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
DA0034644biological_processcellular response to UV
DA0042789biological_processmRNA transcription by RNA polymerase II
DA0043565molecular_functionsequence-specific DNA binding
DA0044024molecular_functionhistone H2AS1 kinase activity
DA0045944biological_processpositive regulation of transcription by RNA polymerase II
DA0046777biological_processprotein autophosphorylation
DA0046982molecular_functionprotein heterodimerization activity
DA0050821biological_processprotein stabilization
DA0051123biological_processRNA polymerase II preinitiation complex assembly
DA0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DA0061628molecular_functionH3K27me3 modified histone binding
DA0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
DA0061631molecular_functionubiquitin conjugating enzyme activity
DA0061733molecular_functionpeptide-lysine-N-acetyltransferase activity
DA0070577molecular_functionlysine-acetylated histone binding
DA0071318biological_processcellular response to ATP
DA0071339cellular_componentMLL1 complex
DA0106310molecular_functionprotein serine kinase activity
DA0140416molecular_functiontranscription regulator inhibitor activity
DA0140566molecular_functionhistone reader activity
DA1901796biological_processregulation of signal transduction by p53 class mediator
DA1902806biological_processregulation of cell cycle G1/S phase transition
DA1905502molecular_functionacetyl-CoA binding
DA1905524biological_processnegative regulation of protein autoubiquitination
DA2000059biological_processnegative regulation of ubiquitin-dependent protein catabolic process
DA2000825biological_processpositive regulation of androgen receptor activity
DB0000086biological_processG2/M transition of mitotic cell cycle
DB0000976molecular_functiontranscription cis-regulatory region binding
DB0003682molecular_functionchromatin binding
DB0005515molecular_functionprotein binding
DB0005634cellular_componentnucleus
DB0005654cellular_componentnucleoplasm
DB0005669cellular_componenttranscription factor TFIID complex
DB0006282biological_processregulation of DNA repair
DB0006357biological_processregulation of transcription by RNA polymerase II
DB0006367biological_processtranscription initiation at RNA polymerase II promoter
DB0014070biological_processresponse to organic cyclic compound
DB0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DB0033276cellular_componenttranscription factor TFTC complex
DB0042789biological_processmRNA transcription by RNA polymerase II
DB0045893biological_processpositive regulation of DNA-templated transcription
DB0051123biological_processRNA polymerase II preinitiation complex assembly
DB0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DD0000785cellular_componentchromatin
DD0001046molecular_functioncore promoter sequence-specific DNA binding
DD0001541biological_processovarian follicle development
DD0001673cellular_componentmale germ cell nucleus
DD0003677molecular_functionDNA binding
DD0005515molecular_functionprotein binding
DD0005634cellular_componentnucleus
DD0005654cellular_componentnucleoplasm
DD0005667cellular_componenttranscription regulator complex
DD0005669cellular_componenttranscription factor TFIID complex
DD0005829cellular_componentcytosol
DD0006282biological_processregulation of DNA repair
DD0006351biological_processDNA-templated transcription
DD0006352biological_processDNA-templated transcription initiation
DD0006357biological_processregulation of transcription by RNA polymerase II
DD0006366biological_processtranscription by RNA polymerase II
DD0006367biological_processtranscription initiation at RNA polymerase II promoter
DD0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DD0017162molecular_functionaryl hydrocarbon receptor binding
DD0032991cellular_componentprotein-containing complex
DD0033276cellular_componenttranscription factor TFTC complex
DD0042789biological_processmRNA transcription by RNA polymerase II
DD0045893biological_processpositive regulation of DNA-templated transcription
DD0046982molecular_functionprotein heterodimerization activity
DD0051123biological_processRNA polymerase II preinitiation complex assembly
DD0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DD0071339cellular_componentMLL1 complex
DE0000785cellular_componentchromatin
DE0005515molecular_functionprotein binding
DE0005634cellular_componentnucleus
DE0005654cellular_componentnucleoplasm
DE0005669cellular_componenttranscription factor TFIID complex
DE0005730cellular_componentnucleolus
DE0006282biological_processregulation of DNA repair
DE0006352biological_processDNA-templated transcription initiation
DE0006357biological_processregulation of transcription by RNA polymerase II
DE0006367biological_processtranscription initiation at RNA polymerase II promoter
DE0015629cellular_componentactin cytoskeleton
DE0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DE0033276cellular_componenttranscription factor TFTC complex
DE0042789biological_processmRNA transcription by RNA polymerase II
DE0042802molecular_functionidentical protein binding
DE0045893biological_processpositive regulation of DNA-templated transcription
DE0051123biological_processRNA polymerase II preinitiation complex assembly
DE0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DF0000124cellular_componentSAGA complex
DF0003677molecular_functionDNA binding
DF0003713molecular_functiontranscription coactivator activity
DF0005515molecular_functionprotein binding
DF0005634cellular_componentnucleus
DF0005654cellular_componentnucleoplasm
DF0005669cellular_componenttranscription factor TFIID complex
DF0005829cellular_componentcytosol
DF0006282biological_processregulation of DNA repair
DF0006352biological_processDNA-templated transcription initiation
DF0006357biological_processregulation of transcription by RNA polymerase II
DF0006366biological_processtranscription by RNA polymerase II
DF0006367biological_processtranscription initiation at RNA polymerase II promoter
DF0006915biological_processapoptotic process
DF0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DF0017162molecular_functionaryl hydrocarbon receptor binding
DF0032991cellular_componentprotein-containing complex
DF0033276cellular_componenttranscription factor TFTC complex
DF0042789biological_processmRNA transcription by RNA polymerase II
DF0045786biological_processnegative regulation of cell cycle
DF0045893biological_processpositive regulation of DNA-templated transcription
DF0046695cellular_componentSLIK (SAGA-like) complex
DF0046982molecular_functionprotein heterodimerization activity
DF0051123biological_processRNA polymerase II preinitiation complex assembly
DF0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DF0071339cellular_componentMLL1 complex
DG0000122biological_processnegative regulation of transcription by RNA polymerase II
DG0000296biological_processspermine transport
DG0000976molecular_functiontranscription cis-regulatory region binding
DG0001097molecular_functionTFIIH-class transcription factor complex binding
DG0001673cellular_componentmale germ cell nucleus
DG0005515molecular_functionprotein binding
DG0005634cellular_componentnucleus
DG0005654cellular_componentnucleoplasm
DG0005667cellular_componenttranscription regulator complex
DG0005669cellular_componenttranscription factor TFIID complex
DG0005737cellular_componentcytoplasm
DG0006282biological_processregulation of DNA repair
DG0006352biological_processDNA-templated transcription initiation
DG0006357biological_processregulation of transcription by RNA polymerase II
DG0006366biological_processtranscription by RNA polymerase II
DG0006367biological_processtranscription initiation at RNA polymerase II promoter
DG0006469biological_processnegative regulation of protein kinase activity
DG0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DG0030520biological_processestrogen receptor signaling pathway
DG0033276cellular_componenttranscription factor TFTC complex
DG0035035molecular_functionhistone acetyltransferase binding
DG0042789biological_processmRNA transcription by RNA polymerase II
DG0042809molecular_functionnuclear vitamin D receptor binding
DG0045344biological_processnegative regulation of MHC class I biosynthetic process
DG0045347biological_processnegative regulation of MHC class II biosynthetic process
DG0045892biological_processnegative regulation of DNA-templated transcription
DG0045893biological_processpositive regulation of DNA-templated transcription
DG0045944biological_processpositive regulation of transcription by RNA polymerase II
DG0046966molecular_functionnuclear thyroid hormone receptor binding
DG0046982molecular_functionprotein heterodimerization activity
DG0051123biological_processRNA polymerase II preinitiation complex assembly
DG0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DG0061628molecular_functionH3K27me3 modified histone binding
DG0071339cellular_componentMLL1 complex
DG0106140molecular_functionP-TEFb complex binding
DG0140297molecular_functionDNA-binding transcription factor binding
DH0001112biological_processDNA-templated transcription open complex formation
DH0001833biological_processinner cell mass cell proliferation
DH0005515molecular_functionprotein binding
DH0005634cellular_componentnucleus
DH0005654cellular_componentnucleoplasm
DH0005669cellular_componenttranscription factor TFIID complex
DH0005737cellular_componentcytoplasm
DH0006367biological_processtranscription initiation at RNA polymerase II promoter
DH0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DH0030154biological_processcell differentiation
DH0042789biological_processmRNA transcription by RNA polymerase II
DH0045598biological_processregulation of fat cell differentiation
DH0046982molecular_functionprotein heterodimerization activity
DH0048471cellular_componentperinuclear region of cytoplasm
DH0051123biological_processRNA polymerase II preinitiation complex assembly
DH0051457biological_processmaintenance of protein location in nucleus
DH0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DI0000124cellular_componentSAGA complex
DI0000492biological_processbox C/D snoRNP assembly
DI0000976molecular_functiontranscription cis-regulatory region binding
DI0002039molecular_functionp53 binding
DI0003677molecular_functionDNA binding
DI0003713molecular_functiontranscription coactivator activity
DI0004402molecular_functionhistone acetyltransferase activity
DI0005515molecular_functionprotein binding
DI0005634cellular_componentnucleus
DI0005654cellular_componentnucleoplasm
DI0005669cellular_componenttranscription factor TFIID complex
DI0006282biological_processregulation of DNA repair
DI0006338biological_processchromatin remodeling
DI0006352biological_processDNA-templated transcription initiation
DI0006355biological_processregulation of DNA-templated transcription
DI0006357biological_processregulation of transcription by RNA polymerase II
DI0006974biological_processDNA damage response
DI0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DI0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
DI0033276cellular_componenttranscription factor TFTC complex
DI0042789biological_processmRNA transcription by RNA polymerase II
DI0043066biological_processnegative regulation of apoptotic process
DI0043484biological_processregulation of RNA splicing
DI0045893biological_processpositive regulation of DNA-templated transcription
DI0045944biological_processpositive regulation of transcription by RNA polymerase II
DI0046982molecular_functionprotein heterodimerization activity
DI0050821biological_processprotein stabilization
DI0051117molecular_functionATPase binding
DI0051123biological_processRNA polymerase II preinitiation complex assembly
DI0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DI0060760biological_processpositive regulation of response to cytokine stimulus
DI0070555biological_processresponse to interleukin-1
DI0070742molecular_functionC2H2 zinc finger domain binding
DI0070761cellular_componentpre-snoRNP complex
DI0071339cellular_componentMLL1 complex
DI0140297molecular_functionDNA-binding transcription factor binding
DI1902065biological_processresponse to L-glutamate
DI1902166biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
DJ0000082biological_processG1/S transition of mitotic cell cycle
DJ0000124cellular_componentSAGA complex
DJ0001673cellular_componentmale germ cell nucleus
DJ0001701biological_processin utero embryonic development
DJ0001756biological_processsomitogenesis
DJ0001889biological_processliver development
DJ0001892biological_processembryonic placenta development
DJ0003677molecular_functionDNA binding
DJ0004402molecular_functionhistone acetyltransferase activity
DJ0005515molecular_functionprotein binding
DJ0005634cellular_componentnucleus
DJ0005654cellular_componentnucleoplasm
DJ0005669cellular_componenttranscription factor TFIID complex
DJ0005737cellular_componentcytoplasm
DJ0006282biological_processregulation of DNA repair
DJ0006338biological_processchromatin remodeling
DJ0006352biological_processDNA-templated transcription initiation
DJ0006355biological_processregulation of DNA-templated transcription
DJ0006357biological_processregulation of transcription by RNA polymerase II
DJ0006366biological_processtranscription by RNA polymerase II
DJ0006367biological_processtranscription initiation at RNA polymerase II promoter
DJ0006915biological_processapoptotic process
DJ0010467biological_processgene expression
DJ0010468biological_processregulation of gene expression
DJ0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DJ0019899molecular_functionenzyme binding
DJ0030331molecular_functionnuclear estrogen receptor binding
DJ0033276cellular_componenttranscription factor TFTC complex
DJ0035264biological_processmulticellular organism growth
DJ0036285biological_processSAGA complex assembly
DJ0042789biological_processmRNA transcription by RNA polymerase II
DJ0042802molecular_functionidentical protein binding
DJ0043484biological_processregulation of RNA splicing
DJ0045893biological_processpositive regulation of DNA-templated transcription
DJ0048371biological_processlateral mesodermal cell differentiation
DJ0048471cellular_componentperinuclear region of cytoplasm
DJ0051123biological_processRNA polymerase II preinitiation complex assembly
DJ0060173biological_processlimb development
DJ0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DJ0065003biological_processprotein-containing complex assembly
DJ0070063molecular_functionRNA polymerase binding
DJ0070365biological_processhepatocyte differentiation
DJ0097550cellular_componenttranscription preinitiation complex
DJ1905069biological_processallantois development
DJ1990841molecular_functionpromoter-specific chromatin binding
DL0000124cellular_componentSAGA complex
DL0003677molecular_functionDNA binding
DL0003713molecular_functiontranscription coactivator activity
DL0005515molecular_functionprotein binding
DL0005634cellular_componentnucleus
DL0005654cellular_componentnucleoplasm
DL0005669cellular_componenttranscription factor TFIID complex
DL0006282biological_processregulation of DNA repair
DL0006352biological_processDNA-templated transcription initiation
DL0006355biological_processregulation of DNA-templated transcription
DL0006357biological_processregulation of transcription by RNA polymerase II
DL0006366biological_processtranscription by RNA polymerase II
DL0006367biological_processtranscription initiation at RNA polymerase II promoter
DL0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DL0017025molecular_functionTBP-class protein binding
DL0033276cellular_componenttranscription factor TFTC complex
DL0042789biological_processmRNA transcription by RNA polymerase II
DL0043484biological_processregulation of RNA splicing
DL0045893biological_processpositive regulation of DNA-templated transcription
DL0045944biological_processpositive regulation of transcription by RNA polymerase II
DL0046982molecular_functionprotein heterodimerization activity
DL0051123biological_processRNA polymerase II preinitiation complex assembly
DL0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DL0140297molecular_functionDNA-binding transcription factor binding
DO0001091molecular_functionRNA polymerase II general transcription initiation factor binding
DO0005515molecular_functionprotein binding
DO0005634cellular_componentnucleus
DO0005654cellular_componentnucleoplasm
DO0005669cellular_componenttranscription factor TFIID complex
DO0005672cellular_componenttranscription factor TFIIA complex
DO0006366biological_processtranscription by RNA polymerase II
DO0006367biological_processtranscription initiation at RNA polymerase II promoter
DO0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DO0017025molecular_functionTBP-class protein binding
DO0030054cellular_componentcell junction
DO0042803molecular_functionprotein homodimerization activity
DO0045944biological_processpositive regulation of transcription by RNA polymerase II
DO0046982molecular_functionprotein heterodimerization activity
DO0051123biological_processRNA polymerase II preinitiation complex assembly
DO0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DO0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
DP0000785cellular_componentchromatin
DP0000791cellular_componenteuchromatin
DP0000976molecular_functiontranscription cis-regulatory region binding
DP0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
DP0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
DP0000995molecular_functionRNA polymerase III general transcription initiation factor activity
DP0001046molecular_functioncore promoter sequence-specific DNA binding
DP0001091molecular_functionRNA polymerase II general transcription initiation factor binding
DP0001093molecular_functionTFIIB-class transcription factor binding
DP0001164molecular_functionRNA polymerase I core promoter sequence-specific DNA binding
DP0001188biological_processRNA polymerase I preinitiation complex assembly
DP0001673cellular_componentmale germ cell nucleus
DP0001674cellular_componentfemale germ cell nucleus
DP0001939cellular_componentfemale pronucleus
DP0001940cellular_componentmale pronucleus
DP0003677molecular_functionDNA binding
DP0005515molecular_functionprotein binding
DP0005634cellular_componentnucleus
DP0005654cellular_componentnucleoplasm
DP0005668cellular_componentRNA polymerase transcription factor SL1 complex
DP0005669cellular_componenttranscription factor TFIID complex
DP0005672cellular_componenttranscription factor TFIIA complex
DP0005737cellular_componentcytoplasm
DP0006352biological_processDNA-templated transcription initiation
DP0006366biological_processtranscription by RNA polymerase II
DP0006367biological_processtranscription initiation at RNA polymerase II promoter
DP0006383biological_processtranscription by RNA polymerase III
DP0007283biological_processspermatogenesis
DP0016251molecular_functionRNA polymerase II general transcription initiation factor activity
DP0017162molecular_functionaryl hydrocarbon receptor binding
DP0019899molecular_functionenzyme binding
DP0032991cellular_componentprotein-containing complex
DP0042789biological_processmRNA transcription by RNA polymerase II
DP0045120cellular_componentpronucleus
DP0045893biological_processpositive regulation of DNA-templated transcription
DP0051123biological_processRNA polymerase II preinitiation complex assembly
DP0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
DP0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
DP0140297molecular_functionDNA-binding transcription factor binding
DQ0005672cellular_componenttranscription factor TFIIA complex
DQ0006367biological_processtranscription initiation at RNA polymerase II promoter
Dc0000122biological_processnegative regulation of transcription by RNA polymerase II
Dc0001673cellular_componentmale germ cell nucleus
Dc0002039molecular_functionp53 binding
Dc0005515molecular_functionprotein binding
Dc0005634cellular_componentnucleus
Dc0005654cellular_componentnucleoplasm
Dc0005669cellular_componenttranscription factor TFIID complex
Dc0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Dc0031965cellular_componentnuclear membrane
Dc0042789biological_processmRNA transcription by RNA polymerase II
Dc0043433biological_processnegative regulation of DNA-binding transcription factor activity
Dc0045944biological_processpositive regulation of transcription by RNA polymerase II
Dc0046872molecular_functionmetal ion binding
Dc0046982molecular_functionprotein heterodimerization activity
Dc0051123biological_processRNA polymerase II preinitiation complex assembly
Dc0051457biological_processmaintenance of protein location in nucleus
Dc0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Dc0140416molecular_functiontranscription regulator inhibitor activity
Dd0000785cellular_componentchromatin
Dd0001046molecular_functioncore promoter sequence-specific DNA binding
Dd0001541biological_processovarian follicle development
Dd0001673cellular_componentmale germ cell nucleus
Dd0003677molecular_functionDNA binding
Dd0005515molecular_functionprotein binding
Dd0005634cellular_componentnucleus
Dd0005654cellular_componentnucleoplasm
Dd0005667cellular_componenttranscription regulator complex
Dd0005669cellular_componenttranscription factor TFIID complex
Dd0005829cellular_componentcytosol
Dd0006282biological_processregulation of DNA repair
Dd0006351biological_processDNA-templated transcription
Dd0006352biological_processDNA-templated transcription initiation
Dd0006357biological_processregulation of transcription by RNA polymerase II
Dd0006366biological_processtranscription by RNA polymerase II
Dd0006367biological_processtranscription initiation at RNA polymerase II promoter
Dd0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Dd0017162molecular_functionaryl hydrocarbon receptor binding
Dd0032991cellular_componentprotein-containing complex
Dd0033276cellular_componenttranscription factor TFTC complex
Dd0042789biological_processmRNA transcription by RNA polymerase II
Dd0045893biological_processpositive regulation of DNA-templated transcription
Dd0046982molecular_functionprotein heterodimerization activity
Dd0051123biological_processRNA polymerase II preinitiation complex assembly
Dd0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Dd0071339cellular_componentMLL1 complex
De0000785cellular_componentchromatin
De0005515molecular_functionprotein binding
De0005634cellular_componentnucleus
De0005654cellular_componentnucleoplasm
De0005669cellular_componenttranscription factor TFIID complex
De0005730cellular_componentnucleolus
De0006282biological_processregulation of DNA repair
De0006352biological_processDNA-templated transcription initiation
De0006357biological_processregulation of transcription by RNA polymerase II
De0006367biological_processtranscription initiation at RNA polymerase II promoter
De0015629cellular_componentactin cytoskeleton
De0016251molecular_functionRNA polymerase II general transcription initiation factor activity
De0033276cellular_componenttranscription factor TFTC complex
De0042789biological_processmRNA transcription by RNA polymerase II
De0042802molecular_functionidentical protein binding
De0045893biological_processpositive regulation of DNA-templated transcription
De0051123biological_processRNA polymerase II preinitiation complex assembly
De0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Df0000124cellular_componentSAGA complex
Df0003677molecular_functionDNA binding
Df0003713molecular_functiontranscription coactivator activity
Df0005515molecular_functionprotein binding
Df0005634cellular_componentnucleus
Df0005654cellular_componentnucleoplasm
Df0005669cellular_componenttranscription factor TFIID complex
Df0005829cellular_componentcytosol
Df0006282biological_processregulation of DNA repair
Df0006352biological_processDNA-templated transcription initiation
Df0006357biological_processregulation of transcription by RNA polymerase II
Df0006366biological_processtranscription by RNA polymerase II
Df0006367biological_processtranscription initiation at RNA polymerase II promoter
Df0006915biological_processapoptotic process
Df0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Df0017162molecular_functionaryl hydrocarbon receptor binding
Df0032991cellular_componentprotein-containing complex
Df0033276cellular_componenttranscription factor TFTC complex
Df0042789biological_processmRNA transcription by RNA polymerase II
Df0045786biological_processnegative regulation of cell cycle
Df0045893biological_processpositive regulation of DNA-templated transcription
Df0046695cellular_componentSLIK (SAGA-like) complex
Df0046982molecular_functionprotein heterodimerization activity
Df0051123biological_processRNA polymerase II preinitiation complex assembly
Df0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Df0071339cellular_componentMLL1 complex
Di0000124cellular_componentSAGA complex
Di0000492biological_processbox C/D snoRNP assembly
Di0000976molecular_functiontranscription cis-regulatory region binding
Di0002039molecular_functionp53 binding
Di0003677molecular_functionDNA binding
Di0003713molecular_functiontranscription coactivator activity
Di0004402molecular_functionhistone acetyltransferase activity
Di0005515molecular_functionprotein binding
Di0005634cellular_componentnucleus
Di0005654cellular_componentnucleoplasm
Di0005669cellular_componenttranscription factor TFIID complex
Di0006282biological_processregulation of DNA repair
Di0006338biological_processchromatin remodeling
Di0006352biological_processDNA-templated transcription initiation
Di0006355biological_processregulation of DNA-templated transcription
Di0006357biological_processregulation of transcription by RNA polymerase II
Di0006974biological_processDNA damage response
Di0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Di0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
Di0033276cellular_componenttranscription factor TFTC complex
Di0042789biological_processmRNA transcription by RNA polymerase II
Di0043066biological_processnegative regulation of apoptotic process
Di0043484biological_processregulation of RNA splicing
Di0045893biological_processpositive regulation of DNA-templated transcription
Di0045944biological_processpositive regulation of transcription by RNA polymerase II
Di0046982molecular_functionprotein heterodimerization activity
Di0050821biological_processprotein stabilization
Di0051117molecular_functionATPase binding
Di0051123biological_processRNA polymerase II preinitiation complex assembly
Di0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Di0060760biological_processpositive regulation of response to cytokine stimulus
Di0070555biological_processresponse to interleukin-1
Di0070742molecular_functionC2H2 zinc finger domain binding
Di0070761cellular_componentpre-snoRNP complex
Di0071339cellular_componentMLL1 complex
Di0140297molecular_functionDNA-binding transcription factor binding
Di1902065biological_processresponse to L-glutamate
Di1902166biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Dj0000082biological_processG1/S transition of mitotic cell cycle
Dj0000124cellular_componentSAGA complex
Dj0001673cellular_componentmale germ cell nucleus
Dj0001701biological_processin utero embryonic development
Dj0001756biological_processsomitogenesis
Dj0001889biological_processliver development
Dj0001892biological_processembryonic placenta development
Dj0003677molecular_functionDNA binding
Dj0004402molecular_functionhistone acetyltransferase activity
Dj0005515molecular_functionprotein binding
Dj0005634cellular_componentnucleus
Dj0005654cellular_componentnucleoplasm
Dj0005669cellular_componenttranscription factor TFIID complex
Dj0005737cellular_componentcytoplasm
Dj0006282biological_processregulation of DNA repair
Dj0006338biological_processchromatin remodeling
Dj0006352biological_processDNA-templated transcription initiation
Dj0006355biological_processregulation of DNA-templated transcription
Dj0006357biological_processregulation of transcription by RNA polymerase II
Dj0006366biological_processtranscription by RNA polymerase II
Dj0006367biological_processtranscription initiation at RNA polymerase II promoter
Dj0006915biological_processapoptotic process
Dj0010467biological_processgene expression
Dj0010468biological_processregulation of gene expression
Dj0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Dj0019899molecular_functionenzyme binding
Dj0030331molecular_functionnuclear estrogen receptor binding
Dj0033276cellular_componenttranscription factor TFTC complex
Dj0035264biological_processmulticellular organism growth
Dj0036285biological_processSAGA complex assembly
Dj0042789biological_processmRNA transcription by RNA polymerase II
Dj0042802molecular_functionidentical protein binding
Dj0043484biological_processregulation of RNA splicing
Dj0045893biological_processpositive regulation of DNA-templated transcription
Dj0048371biological_processlateral mesodermal cell differentiation
Dj0048471cellular_componentperinuclear region of cytoplasm
Dj0051123biological_processRNA polymerase II preinitiation complex assembly
Dj0060173biological_processlimb development
Dj0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Dj0065003biological_processprotein-containing complex assembly
Dj0070063molecular_functionRNA polymerase binding
Dj0070365biological_processhepatocyte differentiation
Dj0097550cellular_componenttranscription preinitiation complex
Dj1905069biological_processallantois development
Dj1990841molecular_functionpromoter-specific chromatin binding
Dk0003713molecular_functiontranscription coactivator activity
Dk0005515molecular_functionprotein binding
Dk0005634cellular_componentnucleus
Dk0005654cellular_componentnucleoplasm
Dk0005669cellular_componenttranscription factor TFIID complex
Dk0005794cellular_componentGolgi apparatus
Dk0006366biological_processtranscription by RNA polymerase II
Dk0006367biological_processtranscription initiation at RNA polymerase II promoter
Dk0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Dk0017025molecular_functionTBP-class protein binding
Dk0042789biological_processmRNA transcription by RNA polymerase II
Dk0042809molecular_functionnuclear vitamin D receptor binding
Dk0043923biological_processpositive regulation by host of viral transcription
Dk0046966molecular_functionnuclear thyroid hormone receptor binding
Dk0046982molecular_functionprotein heterodimerization activity
Dk0051123biological_processRNA polymerase II preinitiation complex assembly
Dk0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Dl0000124cellular_componentSAGA complex
Dl0003677molecular_functionDNA binding
Dl0003713molecular_functiontranscription coactivator activity
Dl0005515molecular_functionprotein binding
Dl0005634cellular_componentnucleus
Dl0005654cellular_componentnucleoplasm
Dl0005669cellular_componenttranscription factor TFIID complex
Dl0006282biological_processregulation of DNA repair
Dl0006352biological_processDNA-templated transcription initiation
Dl0006355biological_processregulation of DNA-templated transcription
Dl0006357biological_processregulation of transcription by RNA polymerase II
Dl0006366biological_processtranscription by RNA polymerase II
Dl0006367biological_processtranscription initiation at RNA polymerase II promoter
Dl0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Dl0017025molecular_functionTBP-class protein binding
Dl0033276cellular_componenttranscription factor TFTC complex
Dl0042789biological_processmRNA transcription by RNA polymerase II
Dl0043484biological_processregulation of RNA splicing
Dl0045893biological_processpositive regulation of DNA-templated transcription
Dl0045944biological_processpositive regulation of transcription by RNA polymerase II
Dl0046982molecular_functionprotein heterodimerization activity
Dl0051123biological_processRNA polymerase II preinitiation complex assembly
Dl0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Dl0140297molecular_functionDNA-binding transcription factor binding
Dm0003677molecular_functionDNA binding
Dm0005515molecular_functionprotein binding
Dm0005634cellular_componentnucleus
Dm0005654cellular_componentnucleoplasm
Dm0005669cellular_componenttranscription factor TFIID complex
Dm0005730cellular_componentnucleolus
Dm0006352biological_processDNA-templated transcription initiation
Dm0006366biological_processtranscription by RNA polymerase II
Dm0006367biological_processtranscription initiation at RNA polymerase II promoter
Dm0016251molecular_functionRNA polymerase II general transcription initiation factor activity
Dm0017025molecular_functionTBP-class protein binding
Dm0042789biological_processmRNA transcription by RNA polymerase II
Dm0046982molecular_functionprotein heterodimerization activity
Dm0051123biological_processRNA polymerase II preinitiation complex assembly
Dm0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
EA0001113biological_processtranscription open complex formation at RNA polymerase II promoter
EA0005515molecular_functionprotein binding
EA0005634cellular_componentnucleus
EA0005654cellular_componentnucleoplasm
EA0005669cellular_componenttranscription factor TFIID complex
EA0005673cellular_componenttranscription factor TFIIE complex
EA0005829cellular_componentcytosol
EA0006366biological_processtranscription by RNA polymerase II
EA0006367biological_processtranscription initiation at RNA polymerase II promoter
EA0016251molecular_functionRNA polymerase II general transcription initiation factor activity
EA0046872molecular_functionmetal ion binding
EB0001097molecular_functionTFIIH-class transcription factor complex binding
EB0003677molecular_functionDNA binding
EB0003723molecular_functionRNA binding
EB0005515molecular_functionprotein binding
EB0005634cellular_componentnucleus
EB0005654cellular_componentnucleoplasm
EB0005669cellular_componenttranscription factor TFIID complex
EB0005673cellular_componenttranscription factor TFIIE complex
EB0005829cellular_componentcytosol
EB0006366biological_processtranscription by RNA polymerase II
EB0006367biological_processtranscription initiation at RNA polymerase II promoter
EB0016251molecular_functionRNA polymerase II general transcription initiation factor activity
FA0001091molecular_functionRNA polymerase II general transcription initiation factor binding
FA0001096molecular_functionTFIIF-class transcription factor complex binding
FA0003677molecular_functionDNA binding
FA0003723molecular_functionRNA binding
FA0005515molecular_functionprotein binding
FA0005634cellular_componentnucleus
FA0005654cellular_componentnucleoplasm
FA0005669cellular_componenttranscription factor TFIID complex
FA0005674cellular_componenttranscription factor TFIIF complex
FA0006366biological_processtranscription by RNA polymerase II
FA0006367biological_processtranscription initiation at RNA polymerase II promoter
FA0006368biological_processtranscription elongation by RNA polymerase II
FA0009615biological_processresponse to virus
FA0016251molecular_functionRNA polymerase II general transcription initiation factor activity
FA0019211molecular_functionphosphatase activator activity
FA0019903molecular_functionprotein phosphatase binding
FA0019904molecular_functionprotein domain specific binding
FA0030054cellular_componentcell junction
FA0032091biological_processnegative regulation of protein binding
FA0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
FA0032991cellular_componentprotein-containing complex
FA0043231cellular_componentintracellular membrane-bounded organelle
FA0045944biological_processpositive regulation of transcription by RNA polymerase II
FA1990841molecular_functionpromoter-specific chromatin binding
FB0003677molecular_functionDNA binding
FB0005515molecular_functionprotein binding
FB0005634cellular_componentnucleus
FB0005654cellular_componentnucleoplasm
FB0005674cellular_componenttranscription factor TFIIF complex
FB0006366biological_processtranscription by RNA polymerase II
FB0006367biological_processtranscription initiation at RNA polymerase II promoter
FB0006368biological_processtranscription elongation by RNA polymerase II
FB0015630cellular_componentmicrotubule cytoskeleton
FB0016251molecular_functionRNA polymerase II general transcription initiation factor activity
FB0045944biological_processpositive regulation of transcription by RNA polymerase II
PA0003677molecular_functionDNA binding
PA0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PA0006351biological_processDNA-templated transcription
PA0006366biological_processtranscription by RNA polymerase II
PB0000428cellular_componentDNA-directed RNA polymerase complex
PB0003677molecular_functionDNA binding
PB0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PB0005654cellular_componentnucleoplasm
PB0006351biological_processDNA-templated transcription
PB0016779molecular_functionnucleotidyltransferase activity
PB0032549molecular_functionribonucleoside binding
PB0046872molecular_functionmetal ion binding
PC0000428cellular_componentDNA-directed RNA polymerase complex
PC0003677molecular_functionDNA binding
PC0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PC0005634cellular_componentnucleus
PC0005654cellular_componentnucleoplasm
PC0005665cellular_componentRNA polymerase II, core complex
PC0005829cellular_componentcytosol
PC0006351biological_processDNA-templated transcription
PC0006366biological_processtranscription by RNA polymerase II
PC0046983molecular_functionprotein dimerization activity
PD0000166molecular_functionnucleotide binding
PD0000428cellular_componentDNA-directed RNA polymerase complex
PD0005634cellular_componentnucleus
PD0006352biological_processDNA-templated transcription initiation
PD0030880cellular_componentRNA polymerase complex
PD0044237biological_processcellular metabolic process
PE0003677molecular_functionDNA binding
PE0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PE0005634cellular_componentnucleus
PE0005654cellular_componentnucleoplasm
PE0006351biological_processDNA-templated transcription
PF0000428cellular_componentDNA-directed RNA polymerase complex
PF0001650cellular_componentfibrillar center
PF0003677molecular_functionDNA binding
PF0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PF0005634cellular_componentnucleus
PF0005654cellular_componentnucleoplasm
PF0005665cellular_componentRNA polymerase II, core complex
PF0005666cellular_componentRNA polymerase III complex
PF0005736cellular_componentRNA polymerase I complex
PF0006351biological_processDNA-templated transcription
PF0006366biological_processtranscription by RNA polymerase II
PG0000428cellular_componentDNA-directed RNA polymerase complex
PG0003676molecular_functionnucleic acid binding
PG0005634cellular_componentnucleus
PG0006351biological_processDNA-templated transcription
PG0006352biological_processDNA-templated transcription initiation
PH0000428cellular_componentDNA-directed RNA polymerase complex
PH0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PH0005634cellular_componentnucleus
PH0005665cellular_componentRNA polymerase II, core complex
PH0006351biological_processDNA-templated transcription
PI0000428cellular_componentDNA-directed RNA polymerase complex
PI0001193biological_processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
PI0003676molecular_functionnucleic acid binding
PI0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PI0005634cellular_componentnucleus
PI0005654cellular_componentnucleoplasm
PI0005665cellular_componentRNA polymerase II, core complex
PI0005730cellular_componentnucleolus
PI0006283biological_processtranscription-coupled nucleotide-excision repair
PI0006351biological_processDNA-templated transcription
PI0006366biological_processtranscription by RNA polymerase II
PI0006367biological_processtranscription initiation at RNA polymerase II promoter
PI0008270molecular_functionzinc ion binding
PI0046872molecular_functionmetal ion binding
PJ0003677molecular_functionDNA binding
PJ0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PJ0006351biological_processDNA-templated transcription
PJ0008270molecular_functionzinc ion binding
PK0000428cellular_componentDNA-directed RNA polymerase complex
PK0001055molecular_functionRNA polymerase II activity
PK0003677molecular_functionDNA binding
PK0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PK0005634cellular_componentnucleus
PK0005665cellular_componentRNA polymerase II, core complex
PK0006351biological_processDNA-templated transcription
PK0006366biological_processtranscription by RNA polymerase II
PK0046983molecular_functionprotein dimerization activity
PL0003677molecular_functionDNA binding
PL0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
PL0005634cellular_componentnucleus
PL0005665cellular_componentRNA polymerase II, core complex
PL0005666cellular_componentRNA polymerase III complex
PL0005736cellular_componentRNA polymerase I complex
PL0006351biological_processDNA-templated transcription
PL0006366biological_processtranscription by RNA polymerase II
PL0008270molecular_functionzinc ion binding
PL0046872molecular_functionmetal ion binding
a0000122biological_processnegative regulation of transcription by RNA polymerase II
a0000151cellular_componentubiquitin ligase complex
a0000785cellular_componentchromatin
a0000902biological_processcell morphogenesis
a0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
a0001223molecular_functiontranscription coactivator binding
a0001525biological_processangiogenesis
a0001701biological_processin utero embryonic development
a0001889biological_processliver development
a0001892biological_processembryonic placenta development
a0002088biological_processlens development in camera-type eye
a0002154biological_processthyroid hormone receptor signaling pathway
a0003222biological_processventricular trabecula myocardium morphogenesis
a0003406biological_processretinal pigment epithelium development
a0003677molecular_functionDNA binding
a0003682molecular_functionchromatin binding
a0003712molecular_functiontranscription coregulator activity
a0003713molecular_functiontranscription coactivator activity
a0003714molecular_functiontranscription corepressor activity
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005654cellular_componentnucleoplasm
a0005730cellular_componentnucleolus
a0006355biological_processregulation of DNA-templated transcription
a0006357biological_processregulation of transcription by RNA polymerase II
a0006590biological_processthyroid hormone generation
a0006606biological_processprotein import into nucleus
a0006702biological_processandrogen biosynthetic process
a0007420biological_processbrain development
a0007507biological_processheart development
a0007595biological_processlactation
a0008284biological_processpositive regulation of cell population proliferation
a0009887biological_processanimal organ morphogenesis
a0010628biological_processpositive regulation of gene expression
a0010839biological_processnegative regulation of keratinocyte proliferation
a0016020cellular_componentmembrane
a0016567biological_processprotein ubiquitination
a0016592cellular_componentmediator complex
a0016922molecular_functionnuclear receptor binding
a0030216biological_processkeratinocyte differentiation
a0030224biological_processmonocyte differentiation
a0030331molecular_functionnuclear estrogen receptor binding
a0030374molecular_functionnuclear receptor coactivator activity
a0030518biological_processnuclear receptor-mediated steroid hormone signaling pathway
a0031100biological_processanimal organ regeneration
a0031490molecular_functionchromatin DNA binding
a0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
a0032993cellular_componentprotein-DNA complex
a0033148biological_processpositive regulation of intracellular estrogen receptor signaling pathway
a0033598biological_processmammary gland epithelial cell proliferation
a0035035molecular_functionhistone acetyltransferase binding
a0035050biological_processembryonic heart tube development
a0035116biological_processembryonic hindlimb morphogenesis
a0035162biological_processembryonic hemopoiesis
a0035357biological_processperoxisome proliferator activated receptor signaling pathway
a0035729biological_processcellular response to hepatocyte growth factor stimulus
a0035855biological_processmegakaryocyte development
a0042789biological_processmRNA transcription by RNA polymerase II
a0042809molecular_functionnuclear vitamin D receptor binding
a0042974molecular_functionnuclear retinoic acid receptor binding
a0042975molecular_functionperoxisome proliferator activated receptor binding
a0043010biological_processcamera-type eye development
a0043066biological_processnegative regulation of apoptotic process
a0044877molecular_functionprotein-containing complex binding
a0045023biological_processG0 to G1 transition
a0045444biological_processfat cell differentiation
a0045618biological_processpositive regulation of keratinocyte differentiation
a0045648biological_processpositive regulation of erythrocyte differentiation
a0045665biological_processnegative regulation of neuron differentiation
a0045893biological_processpositive regulation of DNA-templated transcription
a0045944biological_processpositive regulation of transcription by RNA polymerase II
a0046966molecular_functionnuclear thyroid hormone receptor binding
a0048821biological_processerythrocyte development
a0048822biological_processenucleate erythrocyte development
a0050693molecular_functionLBD domain binding
a0051123biological_processRNA polymerase II preinitiation complex assembly
a0060218biological_processhematopoietic stem cell differentiation
a0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
a0060335biological_processpositive regulation of type II interferon-mediated signaling pathway
a0060744biological_processmammary gland branching involved in thelarche
a0060745biological_processmammary gland branching involved in pregnancy
a0060750biological_processepithelial cell proliferation involved in mammary gland duct elongation
a0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
a0061630molecular_functionubiquitin protein ligase activity
a0070318biological_processpositive regulation of G0 to G1 transition
a0070562biological_processregulation of vitamin D receptor signaling pathway
a0070847cellular_componentcore mediator complex
a0071364biological_processcellular response to epidermal growth factor stimulus
a0071383biological_processcellular response to steroid hormone stimulus
a0097067biological_processcellular response to thyroid hormone stimulus
a0140296molecular_functiongeneral transcription initiation factor binding
a0140297molecular_functionDNA-binding transcription factor binding
a1990841molecular_functionpromoter-specific chromatin binding
a2000347biological_processpositive regulation of hepatocyte proliferation
a2001141biological_processregulation of RNA biosynthetic process
b0003712molecular_functiontranscription coregulator activity
b0005515molecular_functionprotein binding
b0005634cellular_componentnucleus
b0005654cellular_componentnucleoplasm
b0006357biological_processregulation of transcription by RNA polymerase II
b0016592cellular_componentmediator complex
b0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
b0051123biological_processRNA polymerase II preinitiation complex assembly
b0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
b0070847cellular_componentcore mediator complex
c0000151cellular_componentubiquitin ligase complex
c0003713molecular_functiontranscription coactivator activity
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005654cellular_componentnucleoplasm
c0005667cellular_componenttranscription regulator complex
c0005730cellular_componentnucleolus
c0005829cellular_componentcytosol
c0006357biological_processregulation of transcription by RNA polymerase II
c0006367biological_processtranscription initiation at RNA polymerase II promoter
c0016567biological_processprotein ubiquitination
c0016592cellular_componentmediator complex
c0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
c0035019biological_processsomatic stem cell population maintenance
c0051123biological_processRNA polymerase II preinitiation complex assembly
c0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
c0061630molecular_functionubiquitin protein ligase activity
c0070847cellular_componentcore mediator complex
d0003712molecular_functiontranscription coregulator activity
d0003713molecular_functiontranscription coactivator activity
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005654cellular_componentnucleoplasm
d0006357biological_processregulation of transcription by RNA polymerase II
d0006366biological_processtranscription by RNA polymerase II
d0016020cellular_componentmembrane
d0016592cellular_componentmediator complex
d0030374molecular_functionnuclear receptor coactivator activity
d0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
d0042809molecular_functionnuclear vitamin D receptor binding
d0045893biological_processpositive regulation of DNA-templated transcription
d0046966molecular_functionnuclear thyroid hormone receptor binding
d0051123biological_processRNA polymerase II preinitiation complex assembly
d0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
d0070847cellular_componentcore mediator complex
e0003779molecular_functionactin binding
e0005515molecular_functionprotein binding
e0005634cellular_componentnucleus
e0005654cellular_componentnucleoplasm
e0005737cellular_componentcytoplasm
e0005856cellular_componentcytoskeleton
e0016020cellular_componentmembrane
e0016592cellular_componentmediator complex
e0030864cellular_componentcortical actin cytoskeleton
e0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
e0035019biological_processsomatic stem cell population maintenance
e0051123biological_processRNA polymerase II preinitiation complex assembly
e0051151biological_processnegative regulation of smooth muscle cell differentiation
e0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
e0070847cellular_componentcore mediator complex
f0000151cellular_componentubiquitin ligase complex
f0001223molecular_functiontranscription coactivator binding
f0003677molecular_functionDNA binding
f0003712molecular_functiontranscription coregulator activity
f0003713molecular_functiontranscription coactivator activity
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005654cellular_componentnucleoplasm
f0006357biological_processregulation of transcription by RNA polymerase II
f0016020cellular_componentmembrane
f0016567biological_processprotein ubiquitination
f0016592cellular_componentmediator complex
f0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
f0035019biological_processsomatic stem cell population maintenance
f0045944biological_processpositive regulation of transcription by RNA polymerase II
f0051123biological_processRNA polymerase II preinitiation complex assembly
f0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
f0061630molecular_functionubiquitin protein ligase activity
f0070847cellular_componentcore mediator complex
g0000151cellular_componentubiquitin ligase complex
g0003712molecular_functiontranscription coregulator activity
g0003713molecular_functiontranscription coactivator activity
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005654cellular_componentnucleoplasm
g0005667cellular_componenttranscription regulator complex
g0006357biological_processregulation of transcription by RNA polymerase II
g0006367biological_processtranscription initiation at RNA polymerase II promoter
g0016567biological_processprotein ubiquitination
g0016592cellular_componentmediator complex
g0016604cellular_componentnuclear body
g0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
g0035019biological_processsomatic stem cell population maintenance
g0051123biological_processRNA polymerase II preinitiation complex assembly
g0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
g0061630molecular_functionubiquitin protein ligase activity
g0070847cellular_componentcore mediator complex
h0000151cellular_componentubiquitin ligase complex
h0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
h0003712molecular_functiontranscription coregulator activity
h0005515molecular_functionprotein binding
h0005634cellular_componentnucleus
h0005654cellular_componentnucleoplasm
h0006357biological_processregulation of transcription by RNA polymerase II
h0016567biological_processprotein ubiquitination
h0016592cellular_componentmediator complex
h0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
h0051123biological_processRNA polymerase II preinitiation complex assembly
h0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
h0061630molecular_functionubiquitin protein ligase activity
h0070847cellular_componentcore mediator complex
i0003712molecular_functiontranscription coregulator activity
i0005515molecular_functionprotein binding
i0005634cellular_componentnucleus
i0005654cellular_componentnucleoplasm
i0006357biological_processregulation of transcription by RNA polymerase II
i0016592cellular_componentmediator complex
i0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
i0051123biological_processRNA polymerase II preinitiation complex assembly
i0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
i0070847cellular_componentcore mediator complex
j0000151cellular_componentubiquitin ligase complex
j0003712molecular_functiontranscription coregulator activity
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005654cellular_componentnucleoplasm
j0006357biological_processregulation of transcription by RNA polymerase II
j0016567biological_processprotein ubiquitination
j0016592cellular_componentmediator complex
j0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
j0045944biological_processpositive regulation of transcription by RNA polymerase II
j0051123biological_processRNA polymerase II preinitiation complex assembly
j0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
j0061630molecular_functionubiquitin protein ligase activity
j0070847cellular_componentcore mediator complex
k0000151cellular_componentubiquitin ligase complex
k0003712molecular_functiontranscription coregulator activity
k0005515molecular_functionprotein binding
k0005634cellular_componentnucleus
k0005654cellular_componentnucleoplasm
k0006357biological_processregulation of transcription by RNA polymerase II
k0016567biological_processprotein ubiquitination
k0016592cellular_componentmediator complex
k0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
k0051123biological_processRNA polymerase II preinitiation complex assembly
k0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
k0061630molecular_functionubiquitin protein ligase activity
k0070847cellular_componentcore mediator complex
l0000151cellular_componentubiquitin ligase complex
l0003712molecular_functiontranscription coregulator activity
l0003713molecular_functiontranscription coactivator activity
l0005515molecular_functionprotein binding
l0005634cellular_componentnucleus
l0005654cellular_componentnucleoplasm
l0016567biological_processprotein ubiquitination
l0016592cellular_componentmediator complex
l0030374molecular_functionnuclear receptor coactivator activity
l0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
l0035019biological_processsomatic stem cell population maintenance
l0042809molecular_functionnuclear vitamin D receptor binding
l0045893biological_processpositive regulation of DNA-templated transcription
l0046966molecular_functionnuclear thyroid hormone receptor binding
l0051123biological_processRNA polymerase II preinitiation complex assembly
l0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
l0061630molecular_functionubiquitin protein ligase activity
l0070847cellular_componentcore mediator complex
m0000151cellular_componentubiquitin ligase complex
m0003712molecular_functiontranscription coregulator activity
m0005515molecular_functionprotein binding
m0005634cellular_componentnucleus
m0005654cellular_componentnucleoplasm
m0006355biological_processregulation of DNA-templated transcription
m0006357biological_processregulation of transcription by RNA polymerase II
m0016567biological_processprotein ubiquitination
m0016592cellular_componentmediator complex
m0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
m0048147biological_processnegative regulation of fibroblast proliferation
m0051123biological_processRNA polymerase II preinitiation complex assembly
m0060173biological_processlimb development
m0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
m0061630molecular_functionubiquitin protein ligase activity
m0070847cellular_componentcore mediator complex
n0003712molecular_functiontranscription coregulator activity
n0003713molecular_functiontranscription coactivator activity
n0005515molecular_functionprotein binding
n0005634cellular_componentnucleus
n0005654cellular_componentnucleoplasm
n0006357biological_processregulation of transcription by RNA polymerase II
n0016020cellular_componentmembrane
n0016592cellular_componentmediator complex
n0030374molecular_functionnuclear receptor coactivator activity
n0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
n0032991cellular_componentprotein-containing complex
n0035019biological_processsomatic stem cell population maintenance
n0042809molecular_functionnuclear vitamin D receptor binding
n0045893biological_processpositive regulation of DNA-templated transcription
n0045944biological_processpositive regulation of transcription by RNA polymerase II
n0051123biological_processRNA polymerase II preinitiation complex assembly
n0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
n0070847cellular_componentcore mediator complex
o0003712molecular_functiontranscription coregulator activity
o0005515molecular_functionprotein binding
o0005634cellular_componentnucleus
o0005654cellular_componentnucleoplasm
o0005737cellular_componentcytoplasm
o0006355biological_processregulation of DNA-templated transcription
o0016020cellular_componentmembrane
o0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
o0035019biological_processsomatic stem cell population maintenance
o0051123biological_processRNA polymerase II preinitiation complex assembly
o0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
o0070847cellular_componentcore mediator complex
p0003713molecular_functiontranscription coactivator activity
p0005515molecular_functionprotein binding
p0005634cellular_componentnucleus
p0005654cellular_componentnucleoplasm
p0006357biological_processregulation of transcription by RNA polymerase II
p0006366biological_processtranscription by RNA polymerase II
p0016020cellular_componentmembrane
p0016592cellular_componentmediator complex
p0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
p0042809molecular_functionnuclear vitamin D receptor binding
p0045893biological_processpositive regulation of DNA-templated transcription
p0046966molecular_functionnuclear thyroid hormone receptor binding
p0051123biological_processRNA polymerase II preinitiation complex assembly
p0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
p0070847cellular_componentcore mediator complex
q0000151cellular_componentubiquitin ligase complex
q0003712molecular_functiontranscription coregulator activity
q0003713molecular_functiontranscription coactivator activity
q0005515molecular_functionprotein binding
q0005634cellular_componentnucleus
q0005654cellular_componentnucleoplasm
q0005667cellular_componenttranscription regulator complex
q0006357biological_processregulation of transcription by RNA polymerase II
q0006367biological_processtranscription initiation at RNA polymerase II promoter
q0016020cellular_componentmembrane
q0016567biological_processprotein ubiquitination
q0016592cellular_componentmediator complex
q0030374molecular_functionnuclear receptor coactivator activity
q0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
q0035019biological_processsomatic stem cell population maintenance
q0042809molecular_functionnuclear vitamin D receptor binding
q0045893biological_processpositive regulation of DNA-templated transcription
q0045944biological_processpositive regulation of transcription by RNA polymerase II
q0046966molecular_functionnuclear thyroid hormone receptor binding
q0051123biological_processRNA polymerase II preinitiation complex assembly
q0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
q0061630molecular_functionubiquitin protein ligase activity
q0070847cellular_componentcore mediator complex
r0000151cellular_componentubiquitin ligase complex
r0003712molecular_functiontranscription coregulator activity
r0005515molecular_functionprotein binding
r0005634cellular_componentnucleus
r0005654cellular_componentnucleoplasm
r0006357biological_processregulation of transcription by RNA polymerase II
r0006369biological_processtermination of RNA polymerase II transcription
r0016567biological_processprotein ubiquitination
r0016592cellular_componentmediator complex
r0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
r0051123biological_processRNA polymerase II preinitiation complex assembly
r0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
r0061630molecular_functionubiquitin protein ligase activity
r0070847cellular_componentcore mediator complex
s0003712molecular_functiontranscription coregulator activity
s0005515molecular_functionprotein binding
s0005634cellular_componentnucleus
s0005654cellular_componentnucleoplasm
s0006357biological_processregulation of transcription by RNA polymerase II
s0016592cellular_componentmediator complex
s0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
s0045944biological_processpositive regulation of transcription by RNA polymerase II
s0051123biological_processRNA polymerase II preinitiation complex assembly
s0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
s0070847cellular_componentcore mediator complex
t0003712molecular_functiontranscription coregulator activity
t0003713molecular_functiontranscription coactivator activity
t0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
t0005515molecular_functionprotein binding
t0005634cellular_componentnucleus
t0005654cellular_componentnucleoplasm
t0006351biological_processDNA-templated transcription
t0006357biological_processregulation of transcription by RNA polymerase II
t0006366biological_processtranscription by RNA polymerase II
t0016592cellular_componentmediator complex
t0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
t0032991cellular_componentprotein-containing complex
t0035914biological_processskeletal muscle cell differentiation
t0051123biological_processRNA polymerase II preinitiation complex assembly
t0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
t0070847cellular_componentcore mediator complex
u0000151cellular_componentubiquitin ligase complex
u0001824biological_processblastocyst development
u0003712molecular_functiontranscription coregulator activity
u0003713molecular_functiontranscription coactivator activity
u0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
u0005515molecular_functionprotein binding
u0005634cellular_componentnucleus
u0005654cellular_componentnucleoplasm
u0006357biological_processregulation of transcription by RNA polymerase II
u0016567biological_processprotein ubiquitination
u0016592cellular_componentmediator complex
u0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
u0035019biological_processsomatic stem cell population maintenance
u0045944biological_processpositive regulation of transcription by RNA polymerase II
u0051123biological_processRNA polymerase II preinitiation complex assembly
u0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
u0061630molecular_functionubiquitin protein ligase activity
u0070847cellular_componentcore mediator complex
v0003712molecular_functiontranscription coregulator activity
v0005515molecular_functionprotein binding
v0005634cellular_componentnucleus
v0005654cellular_componentnucleoplasm
v0005737cellular_componentcytoplasm
v0006357biological_processregulation of transcription by RNA polymerase II
v0016592cellular_componentmediator complex
v0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
v0051123biological_processRNA polymerase II preinitiation complex assembly
v0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
v0070847cellular_componentcore mediator complex
w0003713molecular_functiontranscription coactivator activity
w0005515molecular_functionprotein binding
w0005634cellular_componentnucleus
w0005654cellular_componentnucleoplasm
w0005667cellular_componenttranscription regulator complex
w0006355biological_processregulation of DNA-templated transcription
w0006357biological_processregulation of transcription by RNA polymerase II
w0006367biological_processtranscription initiation at RNA polymerase II promoter
w0010628biological_processpositive regulation of gene expression
w0016592cellular_componentmediator complex
w0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
w0051123biological_processRNA polymerase II preinitiation complex assembly
w0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
w0070847cellular_componentcore mediator complex
w2000409biological_processpositive regulation of T cell extravasation
x0003712molecular_functiontranscription coregulator activity
x0003713molecular_functiontranscription coactivator activity
x0005515molecular_functionprotein binding
x0005634cellular_componentnucleus
x0005654cellular_componentnucleoplasm
x0016592cellular_componentmediator complex
x0030374molecular_functionnuclear receptor coactivator activity
x0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
x0042809molecular_functionnuclear vitamin D receptor binding
x0045893biological_processpositive regulation of DNA-templated transcription
x0046966molecular_functionnuclear thyroid hormone receptor binding
x0051123biological_processRNA polymerase II preinitiation complex assembly
x0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
x0070847cellular_componentcore mediator complex
z0003712molecular_functiontranscription coregulator activity
z0003713molecular_functiontranscription coactivator activity
z0005515molecular_functionprotein binding
z0005634cellular_componentnucleus
z0005654cellular_componentnucleoplasm
z0006357biological_processregulation of transcription by RNA polymerase II
z0006367biological_processtranscription initiation at RNA polymerase II promoter
z0010628biological_processpositive regulation of gene expression
z0016592cellular_componentmediator complex
z0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
z0051123biological_processRNA polymerase II preinitiation complex assembly
z0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
z0070847cellular_componentcore mediator complex
Functional Information from PROSITE/UniProt
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. SSGMKSSSGLGSSGSL
ChainResidueDetails
aSER1240-LEU1255

site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DNDPSDYVEqdDI
ChainResidueDetails
PCASP136-ILE148

site_idPS00028
Number of Residues21
DetailsZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cav..CqnvFcvdcdvfvHdsl..H
ChainResidueDetails
2CYS360-HIS380

site_idPS00107
Number of Residues25
DetailsPROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGQFATVYkArdkntnqiv.........AIKK
ChainResidueDetails
8LEU18-LYS42

site_idPS00108
Number of Residues13
DetailsPROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IlHrDLKpnNLLL
ChainResidueDetails
8ILE133-LEU145

site_idPS00115
Number of Residues7
DetailsRNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA
ChainResidueDetails
PATYR1593-ALA1599
PATYR1671-SER1677
PATYR1678-SER1684
PATYR1685-SER1691
PATYR1692-SER1698
PATYR1699-SER1705
PATYR1706-SER1712
PATYR1713-SER1719
PATYR1720-SER1726
PATYR1727-SER1733
PATYR1734-SER1740
PATYR1615-SER1621
PATYR1741-ASN1747
PATYR1748-ASN1754
PATYR1755-SER1761
PATYR1762-SER1768
PATYR1769-ASN1775
PATYR1776-ASN1782
PATYR1783-SER1789
PATYR1790-SER1796
PATYR1797-SER1803
PATYR1818-SER1824
PATYR1622-SER1628
PATYR1825-SER1831
PATYR1839-SER1845
PATYR1853-LYS1859
PATYR1860-LYS1866
PATYR1867-LYS1873
PATYR1874-THR1880
PATYR1888-THR1894
PATYR1902-LYS1908
PATYR1909-THR1915
PATYR1916-LYS1922
PATYR1629-SER1635
PATYR1923-THR1929
PATYR1930-LYS1936
PATYR1947-THR1953
PATYR1636-SER1642
PATYR1643-SER1649
PATYR1650-SER1656
PATYR1657-SER1663
PATYR1664-SER1670

site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH
ChainResidueDetails
PITYR112-HIS118

site_idPS00351
Number of Residues50
DetailsTFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV
ChainResidueDetails
DPTYR192-VAL241
DPTYR283-LEU332

site_idPS00446
Number of Residues41
DetailsRNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP
ChainResidueDetails
PCASN32-PRO72

site_idPS00466
Number of Residues38
DetailsZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW
ChainResidueDetails
PICYS86-TRP123

site_idPS00518
Number of Residues10
DetailsZF_RING_1 Zinc finger RING-type signature. CgHtLCesCV
ChainResidueDetails
0CYS26-VAL35

site_idPS00627
Number of Residues12
DetailsGHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. MKsSsGLGSSGS
ChainResidueDetails
aMET1243-SER1254

site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. TypFhtpvNakvvk..DYYkiItrpMdlqtLrenvrkrl..Ypsreefrehlel.IvkNSatY
ChainResidueDetails
DATHR1402-TYR1459
DASER1525-TYR1582

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGsaDrTVRLWDV
ChainResidueDetails
DEVAL642-VAL656
DELEU684-ILE698
DELEU726-ALA740

site_idPS00690
Number of Residues10
DetailsDEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. AvVVFDEAHN
ChainResidueDetails
7ALA229-ASN238

site_idPS00782
Number of Residues16
DetailsTFIIB Transcription factor TFIIB repeat signature. GRandAIASACLYIAC
ChainResidueDetails
BAGLY153-CYS168
BAGLY247-SER262

site_idPS01030
Number of Residues27
DetailsRNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenrillyaCrnC
ChainResidueDetails
PIPHE16-CYS42

site_idPS01110
Number of Residues14
DetailsRNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE
ChainResidueDetails
PEHIS142-GLU155

site_idPS01111
Number of Residues15
DetailsRNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ
ChainResidueDetails
PFTHR58-GLN72

site_idPS01112
Number of Residues10
DetailsRNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG
ChainResidueDetails
PJILE2-GLY11

site_idPS01154
Number of Residues32
DetailsRNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNiIksqLlkdpqVlfagYkvpHP
ChainResidueDetails
PKILE35-PRO66

site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT
ChainResidueDetails
PBGLY932-THR944

site_idPS01359
Number of Residues45
DetailsZF_PHD_1 Zinc finger PHD-type signature. CpgCnkpddgspm....................................IgCdd..Cddw.YHwpCvgimtappeemq.................................WfCpkC
ChainResidueDetails
DcCYS868-CYS912

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
rSER66
FAHIS512
FAGLU517
DPASN257
DPARG294

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
xSER873
BACYS34
BACYS37
DcCYS886
DcHIS891
DcCYS894
DcCYS909
DcCYS912

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163
ChainResidueDetails
FATHR156
DdLYS595
DdLYS597
DdLYS605
DdLYS611
DdLYS621
DdLYS631
DdLYS658
FATHR437
PICYS39
PICYS42
DDLYS611
DDLYS621
DDLYS631
DDLYS658
DdLYS594

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692
ChainResidueDetails
FASER217
BATHR284
BAARG286
BAARG290
PICYS89
PICYS114
PICYS119
BALYS189
BALYS196
BAARG248
BALYS272
BAALA281

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692
ChainResidueDetails
FASER218
FASER224
DASER1799
DASER1802
DAILE1820

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231
ChainResidueDetails
FASER221
DcLYS776

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692
ChainResidueDetails
FATHR331
DiTHR159
DfSER634
DfSER636

site_idSWS_FT_FI8
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163
ChainResidueDetails
FASER377
FASER431

site_idSWS_FT_FI9
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
FASER380
FASER381
FASER436
FASER449

site_idSWS_FT_FI10
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:10428810, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
ChainResidueDetails
FASER385
DiTHR178
DfLYS196

site_idSWS_FT_FI11
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000269|PubMed:10428810, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
FATHR389
DcLYS746

site_idSWS_FT_FI12
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692
ChainResidueDetails
FASER391

site_idSWS_FT_FI13
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
FALYS407

site_idSWS_FT_FI14
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
FASER433
aSER1403

site_idSWS_FT_FI15
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648
ChainResidueDetails
FATHR446

site_idSWS_FT_FI16
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163
ChainResidueDetails
aTHR1440

site_idSWS_FT_FI17
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
aSER1463
aSER1481
aSER1482

site_idSWS_FT_FI18
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
ChainResidueDetails
aSER1479

226707

PDB entries from 2024-10-30

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