7ENC

TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0000082	biological_process	G1/S transition of mitotic cell cycle
0	0000439	cellular_component	transcription factor TFIIH core complex
0	0005515	molecular_function	protein binding
0	0005634	cellular_component	nucleus
0	0005654	cellular_component	nucleoplasm
0	0005675	cellular_component	transcription factor TFIIH holo complex
0	0006281	biological_process	DNA repair
0	0006289	biological_process	nucleotide-excision repair
0	0006351	biological_process	DNA-templated transcription
0	0006357	biological_process	regulation of transcription by RNA polymerase II
0	0006367	biological_process	transcription initiation at RNA polymerase II promoter
0	0008270	molecular_function	zinc ion binding
0	0043066	biological_process	negative regulation of apoptotic process
0	0045737	biological_process	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0	0046872	molecular_function	metal ion binding
0	0048661	biological_process	positive regulation of smooth muscle cell proliferation
0	0061575	molecular_function	cyclin-dependent protein serine/threonine kinase activator activity
0	0070516	cellular_component	CAK-ERCC2 complex
0	0070985	cellular_component	transcription factor TFIIK complex
0	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
1	0000079	biological_process	regulation of cyclin-dependent protein serine/threonine kinase activity
1	0000439	cellular_component	transcription factor TFIIH core complex
1	0003682	molecular_function	chromatin binding
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005654	cellular_component	nucleoplasm
1	0005675	cellular_component	transcription factor TFIIH holo complex
1	0006281	biological_process	DNA repair
1	0006289	biological_process	nucleotide-excision repair
1	0006351	biological_process	DNA-templated transcription
1	0006360	biological_process	transcription by RNA polymerase I
1	0006366	biological_process	transcription by RNA polymerase II
1	0006367	biological_process	transcription initiation at RNA polymerase II promoter
1	0006974	biological_process	DNA damage response
1	0009755	biological_process	hormone-mediated signaling pathway
1	0045893	biological_process	positive regulation of DNA-templated transcription
1	0046966	molecular_function	nuclear thyroid hormone receptor binding
2	0000438	cellular_component	core TFIIH complex portion of holo TFIIH complex
2	0000439	cellular_component	transcription factor TFIIH core complex
2	0002031	biological_process	G protein-coupled receptor internalization
2	0005515	molecular_function	protein binding
2	0005634	cellular_component	nucleus
2	0005654	cellular_component	nucleoplasm
2	0005669	cellular_component	transcription factor TFIID complex
2	0005675	cellular_component	transcription factor TFIIH holo complex
2	0006281	biological_process	DNA repair
2	0006289	biological_process	nucleotide-excision repair
2	0006351	biological_process	DNA-templated transcription
2	0006357	biological_process	regulation of transcription by RNA polymerase II
2	0006366	biological_process	transcription by RNA polymerase II
2	0006367	biological_process	transcription initiation at RNA polymerase II promoter
2	0006974	biological_process	DNA damage response
2	0008270	molecular_function	zinc ion binding
2	0009411	biological_process	response to UV
2	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
2	0016607	cellular_component	nuclear speck
2	0046872	molecular_function	metal ion binding
3	0000438	cellular_component	core TFIIH complex portion of holo TFIIH complex
3	0000439	cellular_component	transcription factor TFIIH core complex
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005654	cellular_component	nucleoplasm
3	0005669	cellular_component	transcription factor TFIID complex
3	0005675	cellular_component	transcription factor TFIIH holo complex
3	0006281	biological_process	DNA repair
3	0006289	biological_process	nucleotide-excision repair
3	0006351	biological_process	DNA-templated transcription
3	0006355	biological_process	regulation of DNA-templated transcription
3	0006366	biological_process	transcription by RNA polymerase II
3	0006367	biological_process	transcription initiation at RNA polymerase II promoter
3	0006974	biological_process	DNA damage response
3	0008270	molecular_function	zinc ion binding
3	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
3	0046872	molecular_function	metal ion binding
3	0097550	cellular_component	transcription preinitiation complex
4	0000438	cellular_component	core TFIIH complex portion of holo TFIIH complex
4	0000439	cellular_component	transcription factor TFIIH core complex
4	0001671	molecular_function	ATPase activator activity
4	0003690	molecular_function	double-stranded DNA binding
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005654	cellular_component	nucleoplasm
4	0005669	cellular_component	transcription factor TFIID complex
4	0005675	cellular_component	transcription factor TFIIH holo complex
4	0006281	biological_process	DNA repair
4	0006289	biological_process	nucleotide-excision repair
4	0006351	biological_process	DNA-templated transcription
4	0006366	biological_process	transcription by RNA polymerase II
4	0006367	biological_process	transcription initiation at RNA polymerase II promoter
4	0006974	biological_process	DNA damage response
4	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
4	0016607	cellular_component	nuclear speck
5	0000439	cellular_component	transcription factor TFIIH core complex
5	0005515	molecular_function	protein binding
5	0005634	cellular_component	nucleus
5	0005654	cellular_component	nucleoplasm
5	0005669	cellular_component	transcription factor TFIID complex
5	0005675	cellular_component	transcription factor TFIIH holo complex
5	0005730	cellular_component	nucleolus
5	0005737	cellular_component	cytoplasm
5	0006281	biological_process	DNA repair
5	0006289	biological_process	nucleotide-excision repair
5	0006294	biological_process	nucleotide-excision repair, preincision complex assembly
5	0006351	biological_process	DNA-templated transcription
5	0006366	biological_process	transcription by RNA polymerase II
5	0006367	biological_process	transcription initiation at RNA polymerase II promoter
5	0006974	biological_process	DNA damage response
6	0000112	cellular_component	nucleotide-excision repair factor 3 complex
6	0000166	molecular_function	nucleotide binding
6	0000439	cellular_component	transcription factor TFIIH core complex
6	0003677	molecular_function	DNA binding
6	0003678	molecular_function	DNA helicase activity
6	0003684	molecular_function	damaged DNA binding
6	0004386	molecular_function	helicase activity
6	0005515	molecular_function	protein binding
6	0005524	molecular_function	ATP binding
6	0005634	cellular_component	nucleus
6	0005654	cellular_component	nucleoplasm
6	0005669	cellular_component	transcription factor TFIID complex
6	0005675	cellular_component	transcription factor TFIIH holo complex
6	0006265	biological_process	DNA topological change
6	0006281	biological_process	DNA repair
6	0006283	biological_process	transcription-coupled nucleotide-excision repair
6	0006289	biological_process	nucleotide-excision repair
6	0006351	biological_process	DNA-templated transcription
6	0006366	biological_process	transcription by RNA polymerase II
6	0006367	biological_process	transcription initiation at RNA polymerase II promoter
6	0006368	biological_process	transcription elongation by RNA polymerase II
6	0006915	biological_process	apoptotic process
6	0006974	biological_process	DNA damage response
6	0006979	biological_process	response to oxidative stress
6	0008104	biological_process	intracellular protein localization
6	0009411	biological_process	response to UV
6	0016787	molecular_function	hydrolase activity
6	0016853	molecular_function	isomerase activity
6	0016887	molecular_function	ATP hydrolysis activity
6	0035315	biological_process	hair cell differentiation
6	0043065	biological_process	positive regulation of apoptotic process
6	0043138	molecular_function	3'-5' DNA helicase activity
6	0048568	biological_process	embryonic organ development
6	0097550	cellular_component	transcription preinitiation complex
6	1901990	biological_process	regulation of mitotic cell cycle phase transition
6	1990841	molecular_function	promoter-specific chromatin binding
7	0000166	molecular_function	nucleotide binding
7	0000439	cellular_component	transcription factor TFIIH core complex
7	0003676	molecular_function	nucleic acid binding
7	0003677	molecular_function	DNA binding
7	0003678	molecular_function	DNA helicase activity
7	0003684	molecular_function	damaged DNA binding
7	0004386	molecular_function	helicase activity
7	0005515	molecular_function	protein binding
7	0005524	molecular_function	ATP binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005669	cellular_component	transcription factor TFIID complex
7	0005675	cellular_component	transcription factor TFIIH holo complex
7	0005737	cellular_component	cytoplasm
7	0005819	cellular_component	spindle
7	0006139	biological_process	nucleobase-containing compound metabolic process
7	0006281	biological_process	DNA repair
7	0006283	biological_process	transcription-coupled nucleotide-excision repair
7	0006289	biological_process	nucleotide-excision repair
7	0006351	biological_process	DNA-templated transcription
7	0006357	biological_process	regulation of transcription by RNA polymerase II
7	0006366	biological_process	transcription by RNA polymerase II
7	0006367	biological_process	transcription initiation at RNA polymerase II promoter
7	0006915	biological_process	apoptotic process
7	0006974	biological_process	DNA damage response
7	0006979	biological_process	response to oxidative stress
7	0007059	biological_process	chromosome segregation
7	0016787	molecular_function	hydrolase activity
7	0016818	molecular_function	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
7	0016853	molecular_function	isomerase activity
7	0016887	molecular_function	ATP hydrolysis activity
7	0030674	molecular_function	protein-macromolecule adaptor activity
7	0035315	biological_process	hair cell differentiation
7	0043139	molecular_function	5'-3' DNA helicase activity
7	0045951	biological_process	positive regulation of mitotic recombination
7	0046872	molecular_function	metal ion binding
7	0051536	molecular_function	iron-sulfur cluster binding
7	0051539	molecular_function	4 iron, 4 sulfur cluster binding
7	0070516	cellular_component	CAK-ERCC2 complex
7	0071817	cellular_component	MMXD complex
7	1901990	biological_process	regulation of mitotic cell cycle phase transition
8	0000166	molecular_function	nucleotide binding
8	0000439	cellular_component	transcription factor TFIIH core complex
8	0001650	cellular_component	fibrillar center
8	0004672	molecular_function	protein kinase activity
8	0004674	molecular_function	protein serine/threonine kinase activity
8	0004693	molecular_function	cyclin-dependent protein serine/threonine kinase activity
8	0005515	molecular_function	protein binding
8	0005524	molecular_function	ATP binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005675	cellular_component	transcription factor TFIIH holo complex
8	0005737	cellular_component	cytoplasm
8	0005829	cellular_component	cytosol
8	0006281	biological_process	DNA repair
8	0006289	biological_process	nucleotide-excision repair
8	0006351	biological_process	DNA-templated transcription
8	0006366	biological_process	transcription by RNA polymerase II
8	0006367	biological_process	transcription initiation at RNA polymerase II promoter
8	0006468	biological_process	protein phosphorylation
8	0006974	biological_process	DNA damage response
8	0008094	molecular_function	ATP-dependent activity, acting on DNA
8	0008353	molecular_function	RNA polymerase II CTD heptapeptide repeat kinase activity
8	0016301	molecular_function	kinase activity
8	0016740	molecular_function	transferase activity
8	0042795	biological_process	snRNA transcription by RNA polymerase II
8	0045944	biological_process	positive regulation of transcription by RNA polymerase II
8	0048471	cellular_component	perinuclear region of cytoplasm
8	0050821	biological_process	protein stabilization
8	0051301	biological_process	cell division
8	0051726	biological_process	regulation of cell cycle
8	0070516	cellular_component	CAK-ERCC2 complex
8	0070985	cellular_component	transcription factor TFIIK complex
8	0106310	molecular_function	protein serine kinase activity
8	0140836	molecular_function	RNA polymerase II CTD heptapeptide repeat S5 kinase activity
8	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
9	0000307	cellular_component	cyclin-dependent protein kinase holoenzyme complex
9	0000439	cellular_component	transcription factor TFIIH core complex
9	0005515	molecular_function	protein binding
9	0005634	cellular_component	nucleus
9	0005654	cellular_component	nucleoplasm
9	0005675	cellular_component	transcription factor TFIIH holo complex
9	0006289	biological_process	nucleotide-excision repair
9	0006351	biological_process	DNA-templated transcription
9	0006357	biological_process	regulation of transcription by RNA polymerase II
9	0006367	biological_process	transcription initiation at RNA polymerase II promoter
9	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
9	0016301	molecular_function	kinase activity
9	0016538	molecular_function	cyclin-dependent protein serine/threonine kinase regulator activity
9	0050821	biological_process	protein stabilization
9	0070516	cellular_component	CAK-ERCC2 complex
9	0070985	cellular_component	transcription factor TFIIK complex
9	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
a	0000122	biological_process	negative regulation of transcription by RNA polymerase II
a	0000151	cellular_component	ubiquitin ligase complex
a	0000785	cellular_component	chromatin
a	0000902	biological_process	cell morphogenesis
a	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
a	0001223	molecular_function	transcription coactivator binding
a	0001525	biological_process	angiogenesis
a	0002088	biological_process	lens development in camera-type eye
a	0002154	biological_process	thyroid hormone receptor signaling pathway
a	0003222	biological_process	ventricular trabecula myocardium morphogenesis
a	0003406	biological_process	retinal pigment epithelium development
a	0003677	molecular_function	DNA binding
a	0003682	molecular_function	chromatin binding
a	0003712	molecular_function	transcription coregulator activity
a	0003713	molecular_function	transcription coactivator activity
a	0003714	molecular_function	transcription corepressor activity
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005730	cellular_component	nucleolus
a	0006351	biological_process	DNA-templated transcription
a	0006357	biological_process	regulation of transcription by RNA polymerase II
a	0006702	biological_process	androgen biosynthetic process
a	0010628	biological_process	positive regulation of gene expression
a	0010839	biological_process	negative regulation of keratinocyte proliferation
a	0016020	cellular_component	membrane
a	0016567	biological_process	protein ubiquitination
a	0016592	cellular_component	mediator complex
a	0016922	molecular_function	nuclear receptor binding
a	0030216	biological_process	keratinocyte differentiation
a	0030331	molecular_function	nuclear estrogen receptor binding
a	0030518	biological_process	nuclear receptor-mediated steroid hormone signaling pathway
a	0031490	molecular_function	chromatin DNA binding
a	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
a	0032993	cellular_component	protein-DNA complex
a	0035035	molecular_function	histone acetyltransferase binding
a	0035855	biological_process	megakaryocyte development
a	0042789	biological_process	mRNA transcription by RNA polymerase II
a	0042809	molecular_function	nuclear vitamin D receptor binding
a	0042974	molecular_function	nuclear retinoic acid receptor binding
a	0042975	molecular_function	peroxisome proliferator activated receptor binding
a	0043066	biological_process	negative regulation of apoptotic process
a	0044877	molecular_function	protein-containing complex binding
a	0045444	biological_process	fat cell differentiation
a	0045618	biological_process	positive regulation of keratinocyte differentiation
a	0045648	biological_process	positive regulation of erythrocyte differentiation
a	0045665	biological_process	negative regulation of neuron differentiation
a	0045893	biological_process	positive regulation of DNA-templated transcription
a	0045944	biological_process	positive regulation of transcription by RNA polymerase II
a	0046966	molecular_function	nuclear thyroid hormone receptor binding
a	0048821	biological_process	erythrocyte development
a	0050693	molecular_function	LBD domain binding
a	0051123	biological_process	RNA polymerase II preinitiation complex assembly
a	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
a	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
a	0061630	molecular_function	ubiquitin protein ligase activity
a	0071364	biological_process	cellular response to epidermal growth factor stimulus
a	0071383	biological_process	cellular response to steroid hormone stimulus
a	0097067	biological_process	cellular response to thyroid hormone stimulus
a	0140296	molecular_function	general transcription initiation factor binding
a	0140297	molecular_function	DNA-binding transcription factor binding
a	1990841	molecular_function	promoter-specific chromatin binding
a	2001141	biological_process	regulation of RNA biosynthetic process
b	0003712	molecular_function	transcription coregulator activity
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0006351	biological_process	DNA-templated transcription
b	0006357	biological_process	regulation of transcription by RNA polymerase II
b	0016592	cellular_component	mediator complex
b	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
b	0051123	biological_process	RNA polymerase II preinitiation complex assembly
b	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
BA	0000776	cellular_component	kinetochore
BA	0000793	cellular_component	condensed chromosome
BA	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
BA	0000993	molecular_function	RNA polymerase II complex binding
BA	0001174	biological_process	transcriptional start site selection at RNA polymerase II promoter
BA	0003677	molecular_function	DNA binding
BA	0005515	molecular_function	protein binding
BA	0005634	cellular_component	nucleus
BA	0005654	cellular_component	nucleoplasm
BA	0005669	cellular_component	transcription factor TFIID complex
BA	0005694	cellular_component	chromosome
BA	0006351	biological_process	DNA-templated transcription
BA	0006352	biological_process	DNA-templated transcription initiation
BA	0006366	biological_process	transcription by RNA polymerase II
BA	0006367	biological_process	transcription initiation at RNA polymerase II promoter
BA	0006473	biological_process	protein acetylation
BA	0008270	molecular_function	zinc ion binding
BA	0010467	biological_process	gene expression
BA	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
BA	0016407	molecular_function	acetyltransferase activity
BA	0016604	cellular_component	nuclear body
BA	0016740	molecular_function	transferase activity
BA	0016746	molecular_function	acyltransferase activity
BA	0017025	molecular_function	TBP-class protein binding
BA	0019083	biological_process	viral transcription
BA	0032153	cellular_component	cell division site
BA	0032993	cellular_component	protein-DNA complex
BA	0042585	cellular_component	germinal vesicle
BA	0046872	molecular_function	metal ion binding
BA	0046966	molecular_function	nuclear thyroid hormone receptor binding
BA	0051123	biological_process	RNA polymerase II preinitiation complex assembly
BA	0051177	biological_process	meiotic sister chromatid cohesion
BA	0051225	biological_process	spindle assembly
BA	0051276	biological_process	chromosome organization
BA	0061733	molecular_function	protein-lysine-acetyltransferase activity
BA	0070897	biological_process	transcription preinitiation complex assembly
BA	0090575	cellular_component	RNA polymerase II transcription regulator complex
BA	0097550	cellular_component	transcription preinitiation complex
BA	0140297	molecular_function	DNA-binding transcription factor binding
BA	1904798	biological_process	positive regulation of core promoter binding
BA	1990114	biological_process	RNA polymerase II core complex assembly
BA	1990841	molecular_function	promoter-specific chromatin binding
c	0000151	cellular_component	ubiquitin ligase complex
c	0003713	molecular_function	transcription coactivator activity
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005667	cellular_component	transcription regulator complex
c	0005730	cellular_component	nucleolus
c	0006351	biological_process	DNA-templated transcription
c	0006357	biological_process	regulation of transcription by RNA polymerase II
c	0006367	biological_process	transcription initiation at RNA polymerase II promoter
c	0016567	biological_process	protein ubiquitination
c	0016592	cellular_component	mediator complex
c	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
c	0051123	biological_process	RNA polymerase II preinitiation complex assembly
c	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
c	0061630	molecular_function	ubiquitin protein ligase activity
d	0003712	molecular_function	transcription coregulator activity
d	0003713	molecular_function	transcription coactivator activity
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0006351	biological_process	DNA-templated transcription
d	0006357	biological_process	regulation of transcription by RNA polymerase II
d	0006366	biological_process	transcription by RNA polymerase II
d	0016020	cellular_component	membrane
d	0016592	cellular_component	mediator complex
d	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
d	0042809	molecular_function	nuclear vitamin D receptor binding
d	0045893	biological_process	positive regulation of DNA-templated transcription
d	0046966	molecular_function	nuclear thyroid hormone receptor binding
d	0051123	biological_process	RNA polymerase II preinitiation complex assembly
d	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
d	0070847	cellular_component	core mediator complex
DA	0000122	biological_process	negative regulation of transcription by RNA polymerase II
DA	0000166	molecular_function	nucleotide binding
DA	0000209	biological_process	protein polyubiquitination
DA	0000785	cellular_component	chromatin
DA	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
DA	0001091	molecular_function	RNA polymerase II general transcription initiation factor binding
DA	0001181	molecular_function	RNA polymerase I general transcription initiation factor activity
DA	0002039	molecular_function	p53 binding
DA	0003677	molecular_function	DNA binding
DA	0004402	molecular_function	histone acetyltransferase activity
DA	0004672	molecular_function	protein kinase activity
DA	0004674	molecular_function	protein serine/threonine kinase activity
DA	0005515	molecular_function	protein binding
DA	0005524	molecular_function	ATP binding
DA	0005634	cellular_component	nucleus
DA	0005654	cellular_component	nucleoplasm
DA	0005667	cellular_component	transcription regulator complex
DA	0005669	cellular_component	transcription factor TFIID complex
DA	0005730	cellular_component	nucleolus
DA	0006325	biological_process	chromatin organization
DA	0006338	biological_process	chromatin remodeling
DA	0006351	biological_process	DNA-templated transcription
DA	0006352	biological_process	DNA-templated transcription initiation
DA	0006361	biological_process	transcription initiation at RNA polymerase I promoter
DA	0006366	biological_process	transcription by RNA polymerase II
DA	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DA	0006511	biological_process	ubiquitin-dependent protein catabolic process
DA	0006974	biological_process	DNA damage response
DA	0010629	biological_process	negative regulation of gene expression
DA	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DA	0016301	molecular_function	kinase activity
DA	0016740	molecular_function	transferase activity
DA	0016746	molecular_function	acyltransferase activity
DA	0016922	molecular_function	nuclear receptor binding
DA	0017025	molecular_function	TBP-class protein binding
DA	0030901	biological_process	midbrain development
DA	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
DA	0034644	biological_process	cellular response to UV
DA	0042789	biological_process	mRNA transcription by RNA polymerase II
DA	0043565	molecular_function	sequence-specific DNA binding
DA	0045944	biological_process	positive regulation of transcription by RNA polymerase II
DA	0046777	biological_process	protein autophosphorylation
DA	0046982	molecular_function	protein heterodimerization activity
DA	0050821	biological_process	protein stabilization
DA	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DA	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DA	0061628	molecular_function	histone H3K27me3 reader activity
DA	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
DA	0061631	molecular_function	ubiquitin conjugating enzyme activity
DA	0061733	molecular_function	protein-lysine-acetyltransferase activity
DA	0071318	biological_process	cellular response to ATP
DA	0071339	cellular_component	MLL1 complex
DA	0106310	molecular_function	protein serine kinase activity
DA	0140046	molecular_function	histone H4K16ac reader activity
DA	0140416	molecular_function	transcription regulator inhibitor activity
DA	0140566	molecular_function	histone reader activity
DA	0160207	biological_process	positive regulation of androgen receptor signaling pathway
DA	1901796	biological_process	regulation of signal transduction by p53 class mediator
DA	1901797	biological_process	negative regulation of signal transduction by p53 class mediator
DA	1902806	biological_process	regulation of cell cycle G1/S phase transition
DA	1905502	molecular_function	acetyl-CoA binding
DA	1905524	biological_process	negative regulation of protein autoubiquitination
DA	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
DB	0000086	biological_process	G2/M transition of mitotic cell cycle
DB	0000976	molecular_function	transcription cis-regulatory region binding
DB	0003682	molecular_function	chromatin binding
DB	0005515	molecular_function	protein binding
DB	0005634	cellular_component	nucleus
DB	0005654	cellular_component	nucleoplasm
DB	0005669	cellular_component	transcription factor TFIID complex
DB	0006282	biological_process	regulation of DNA repair
DB	0006351	biological_process	DNA-templated transcription
DB	0006357	biological_process	regulation of transcription by RNA polymerase II
DB	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DB	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DB	0033276	cellular_component	transcription factor TFTC complex
DB	0042789	biological_process	mRNA transcription by RNA polymerase II
DB	0045893	biological_process	positive regulation of DNA-templated transcription
DB	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DB	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DB	1901562	biological_process	response to paraquat
Dc	0000122	biological_process	negative regulation of transcription by RNA polymerase II
Dc	0002039	molecular_function	p53 binding
Dc	0005515	molecular_function	protein binding
Dc	0005634	cellular_component	nucleus
Dc	0005654	cellular_component	nucleoplasm
Dc	0005669	cellular_component	transcription factor TFIID complex
Dc	0006325	biological_process	chromatin organization
Dc	0006351	biological_process	DNA-templated transcription
Dc	0006366	biological_process	transcription by RNA polymerase II
Dc	0008270	molecular_function	zinc ion binding
Dc	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Dc	0031965	cellular_component	nuclear membrane
Dc	0042789	biological_process	mRNA transcription by RNA polymerase II
Dc	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Dc	0046872	molecular_function	metal ion binding
Dc	0046982	molecular_function	protein heterodimerization activity
Dc	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Dc	0051457	biological_process	maintenance of protein location in nucleus
Dc	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Dc	0140002	molecular_function	histone H3K4me3 reader activity
Dc	0140416	molecular_function	transcription regulator inhibitor activity
Dc	1901797	biological_process	negative regulation of signal transduction by p53 class mediator
Dd	0000785	cellular_component	chromatin
Dd	0001046	molecular_function	core promoter sequence-specific DNA binding
Dd	0003677	molecular_function	DNA binding
Dd	0005515	molecular_function	protein binding
Dd	0005634	cellular_component	nucleus
Dd	0005654	cellular_component	nucleoplasm
Dd	0005669	cellular_component	transcription factor TFIID complex
Dd	0006282	biological_process	regulation of DNA repair
Dd	0006351	biological_process	DNA-templated transcription
Dd	0006352	biological_process	DNA-templated transcription initiation
Dd	0006357	biological_process	regulation of transcription by RNA polymerase II
Dd	0006366	biological_process	transcription by RNA polymerase II
Dd	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Dd	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Dd	0017162	molecular_function	aryl hydrocarbon receptor binding
Dd	0032991	cellular_component	protein-containing complex
Dd	0033276	cellular_component	transcription factor TFTC complex
Dd	0042789	biological_process	mRNA transcription by RNA polymerase II
Dd	0045893	biological_process	positive regulation of DNA-templated transcription
Dd	0046982	molecular_function	protein heterodimerization activity
Dd	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Dd	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Dd	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
Dd	0071339	cellular_component	MLL1 complex
DD	0000785	cellular_component	chromatin
DD	0001046	molecular_function	core promoter sequence-specific DNA binding
DD	0003677	molecular_function	DNA binding
DD	0005515	molecular_function	protein binding
DD	0005634	cellular_component	nucleus
DD	0005654	cellular_component	nucleoplasm
DD	0005669	cellular_component	transcription factor TFIID complex
DD	0006282	biological_process	regulation of DNA repair
DD	0006351	biological_process	DNA-templated transcription
DD	0006352	biological_process	DNA-templated transcription initiation
DD	0006357	biological_process	regulation of transcription by RNA polymerase II
DD	0006366	biological_process	transcription by RNA polymerase II
DD	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DD	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DD	0017162	molecular_function	aryl hydrocarbon receptor binding
DD	0032991	cellular_component	protein-containing complex
DD	0033276	cellular_component	transcription factor TFTC complex
DD	0042789	biological_process	mRNA transcription by RNA polymerase II
DD	0045893	biological_process	positive regulation of DNA-templated transcription
DD	0046982	molecular_function	protein heterodimerization activity
DD	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DD	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DD	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
DD	0071339	cellular_component	MLL1 complex
De	0000785	cellular_component	chromatin
De	0005515	molecular_function	protein binding
De	0005634	cellular_component	nucleus
De	0005654	cellular_component	nucleoplasm
De	0005669	cellular_component	transcription factor TFIID complex
De	0005730	cellular_component	nucleolus
De	0006282	biological_process	regulation of DNA repair
De	0006351	biological_process	DNA-templated transcription
De	0006352	biological_process	DNA-templated transcription initiation
De	0006357	biological_process	regulation of transcription by RNA polymerase II
De	0006367	biological_process	transcription initiation at RNA polymerase II promoter
De	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
De	0033276	cellular_component	transcription factor TFTC complex
De	0042789	biological_process	mRNA transcription by RNA polymerase II
De	0042802	molecular_function	identical protein binding
De	0045893	biological_process	positive regulation of DNA-templated transcription
De	0051123	biological_process	RNA polymerase II preinitiation complex assembly
De	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DE	0000785	cellular_component	chromatin
DE	0005515	molecular_function	protein binding
DE	0005634	cellular_component	nucleus
DE	0005654	cellular_component	nucleoplasm
DE	0005669	cellular_component	transcription factor TFIID complex
DE	0005730	cellular_component	nucleolus
DE	0006282	biological_process	regulation of DNA repair
DE	0006351	biological_process	DNA-templated transcription
DE	0006352	biological_process	DNA-templated transcription initiation
DE	0006357	biological_process	regulation of transcription by RNA polymerase II
DE	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DE	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DE	0033276	cellular_component	transcription factor TFTC complex
DE	0042789	biological_process	mRNA transcription by RNA polymerase II
DE	0042802	molecular_function	identical protein binding
DE	0045893	biological_process	positive regulation of DNA-templated transcription
DE	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DE	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Df	0000124	cellular_component	SAGA complex
Df	0003677	molecular_function	DNA binding
Df	0003713	molecular_function	transcription coactivator activity
Df	0005515	molecular_function	protein binding
Df	0005634	cellular_component	nucleus
Df	0005654	cellular_component	nucleoplasm
Df	0005669	cellular_component	transcription factor TFIID complex
Df	0006282	biological_process	regulation of DNA repair
Df	0006351	biological_process	DNA-templated transcription
Df	0006352	biological_process	DNA-templated transcription initiation
Df	0006357	biological_process	regulation of transcription by RNA polymerase II
Df	0006366	biological_process	transcription by RNA polymerase II
Df	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Df	0006915	biological_process	apoptotic process
Df	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Df	0017162	molecular_function	aryl hydrocarbon receptor binding
Df	0032991	cellular_component	protein-containing complex
Df	0033276	cellular_component	transcription factor TFTC complex
Df	0042789	biological_process	mRNA transcription by RNA polymerase II
Df	0045786	biological_process	negative regulation of cell cycle
Df	0045893	biological_process	positive regulation of DNA-templated transcription
Df	0046695	cellular_component	SLIK (SAGA-like) complex
Df	0046982	molecular_function	protein heterodimerization activity
Df	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Df	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Df	0071339	cellular_component	MLL1 complex
DF	0000124	cellular_component	SAGA complex
DF	0003677	molecular_function	DNA binding
DF	0003713	molecular_function	transcription coactivator activity
DF	0005515	molecular_function	protein binding
DF	0005634	cellular_component	nucleus
DF	0005654	cellular_component	nucleoplasm
DF	0005669	cellular_component	transcription factor TFIID complex
DF	0006282	biological_process	regulation of DNA repair
DF	0006351	biological_process	DNA-templated transcription
DF	0006352	biological_process	DNA-templated transcription initiation
DF	0006357	biological_process	regulation of transcription by RNA polymerase II
DF	0006366	biological_process	transcription by RNA polymerase II
DF	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DF	0006915	biological_process	apoptotic process
DF	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DF	0017162	molecular_function	aryl hydrocarbon receptor binding
DF	0032991	cellular_component	protein-containing complex
DF	0033276	cellular_component	transcription factor TFTC complex
DF	0042789	biological_process	mRNA transcription by RNA polymerase II
DF	0045786	biological_process	negative regulation of cell cycle
DF	0045893	biological_process	positive regulation of DNA-templated transcription
DF	0046695	cellular_component	SLIK (SAGA-like) complex
DF	0046982	molecular_function	protein heterodimerization activity
DF	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DF	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DF	0071339	cellular_component	MLL1 complex
DG	0000122	biological_process	negative regulation of transcription by RNA polymerase II
DG	0000296	biological_process	spermine transport
DG	0000976	molecular_function	transcription cis-regulatory region binding
DG	0001097	molecular_function	TFIIH-class transcription factor complex binding
DG	0005515	molecular_function	protein binding
DG	0005634	cellular_component	nucleus
DG	0005654	cellular_component	nucleoplasm
DG	0005667	cellular_component	transcription regulator complex
DG	0005669	cellular_component	transcription factor TFIID complex
DG	0005737	cellular_component	cytoplasm
DG	0006282	biological_process	regulation of DNA repair
DG	0006325	biological_process	chromatin organization
DG	0006351	biological_process	DNA-templated transcription
DG	0006352	biological_process	DNA-templated transcription initiation
DG	0006357	biological_process	regulation of transcription by RNA polymerase II
DG	0006366	biological_process	transcription by RNA polymerase II
DG	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DG	0006469	biological_process	negative regulation of protein kinase activity
DG	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DG	0033276	cellular_component	transcription factor TFTC complex
DG	0035035	molecular_function	histone acetyltransferase binding
DG	0042789	biological_process	mRNA transcription by RNA polymerase II
DG	0042809	molecular_function	nuclear vitamin D receptor binding
DG	0045344	biological_process	negative regulation of MHC class I biosynthetic process
DG	0045347	biological_process	negative regulation of MHC class II biosynthetic process
DG	0045892	biological_process	negative regulation of DNA-templated transcription
DG	0045893	biological_process	positive regulation of DNA-templated transcription
DG	0045944	biological_process	positive regulation of transcription by RNA polymerase II
DG	0046966	molecular_function	nuclear thyroid hormone receptor binding
DG	0046982	molecular_function	protein heterodimerization activity
DG	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DG	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DG	0061628	molecular_function	histone H3K27me3 reader activity
DG	0071339	cellular_component	MLL1 complex
DG	0106140	molecular_function	P-TEFb complex binding
DG	0140297	molecular_function	DNA-binding transcription factor binding
DH	0001112	biological_process	DNA-templated transcription open complex formation
DH	0005515	molecular_function	protein binding
DH	0005634	cellular_component	nucleus
DH	0005654	cellular_component	nucleoplasm
DH	0005669	cellular_component	transcription factor TFIID complex
DH	0005737	cellular_component	cytoplasm
DH	0006351	biological_process	DNA-templated transcription
DH	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DH	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DH	0030154	biological_process	cell differentiation
DH	0042789	biological_process	mRNA transcription by RNA polymerase II
DH	0045598	biological_process	regulation of fat cell differentiation
DH	0046982	molecular_function	protein heterodimerization activity
DH	0048471	cellular_component	perinuclear region of cytoplasm
DH	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DH	0051457	biological_process	maintenance of protein location in nucleus
DH	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Di	0000124	cellular_component	SAGA complex
Di	0000492	biological_process	box C/D snoRNP assembly
Di	0000976	molecular_function	transcription cis-regulatory region binding
Di	0002039	molecular_function	p53 binding
Di	0003677	molecular_function	DNA binding
Di	0003713	molecular_function	transcription coactivator activity
Di	0004402	molecular_function	histone acetyltransferase activity
Di	0005515	molecular_function	protein binding
Di	0005634	cellular_component	nucleus
Di	0005654	cellular_component	nucleoplasm
Di	0005669	cellular_component	transcription factor TFIID complex
Di	0006282	biological_process	regulation of DNA repair
Di	0006338	biological_process	chromatin remodeling
Di	0006351	biological_process	DNA-templated transcription
Di	0006352	biological_process	DNA-templated transcription initiation
Di	0006355	biological_process	regulation of DNA-templated transcription
Di	0006357	biological_process	regulation of transcription by RNA polymerase II
Di	0006974	biological_process	DNA damage response
Di	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Di	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
Di	0033276	cellular_component	transcription factor TFTC complex
Di	0042789	biological_process	mRNA transcription by RNA polymerase II
Di	0043066	biological_process	negative regulation of apoptotic process
Di	0043484	biological_process	regulation of RNA splicing
Di	0045893	biological_process	positive regulation of DNA-templated transcription
Di	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Di	0046982	molecular_function	protein heterodimerization activity
Di	0050821	biological_process	protein stabilization
Di	0051117	molecular_function	ATPase binding
Di	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Di	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Di	0060760	biological_process	positive regulation of response to cytokine stimulus
Di	0070555	biological_process	response to interleukin-1
Di	0070742	molecular_function	C2H2 zinc finger domain binding
Di	0070761	cellular_component	pre-snoRNP complex
Di	0071339	cellular_component	MLL1 complex
Di	0140297	molecular_function	DNA-binding transcription factor binding
Di	1902166	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
DI	0000124	cellular_component	SAGA complex
DI	0000492	biological_process	box C/D snoRNP assembly
DI	0000976	molecular_function	transcription cis-regulatory region binding
DI	0002039	molecular_function	p53 binding
DI	0003677	molecular_function	DNA binding
DI	0003713	molecular_function	transcription coactivator activity
DI	0004402	molecular_function	histone acetyltransferase activity
DI	0005515	molecular_function	protein binding
DI	0005634	cellular_component	nucleus
DI	0005654	cellular_component	nucleoplasm
DI	0005669	cellular_component	transcription factor TFIID complex
DI	0006282	biological_process	regulation of DNA repair
DI	0006338	biological_process	chromatin remodeling
DI	0006351	biological_process	DNA-templated transcription
DI	0006352	biological_process	DNA-templated transcription initiation
DI	0006355	biological_process	regulation of DNA-templated transcription
DI	0006357	biological_process	regulation of transcription by RNA polymerase II
DI	0006974	biological_process	DNA damage response
DI	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DI	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
DI	0033276	cellular_component	transcription factor TFTC complex
DI	0042789	biological_process	mRNA transcription by RNA polymerase II
DI	0043066	biological_process	negative regulation of apoptotic process
DI	0043484	biological_process	regulation of RNA splicing
DI	0045893	biological_process	positive regulation of DNA-templated transcription
DI	0045944	biological_process	positive regulation of transcription by RNA polymerase II
DI	0046982	molecular_function	protein heterodimerization activity
DI	0050821	biological_process	protein stabilization
DI	0051117	molecular_function	ATPase binding
DI	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DI	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DI	0060760	biological_process	positive regulation of response to cytokine stimulus
DI	0070555	biological_process	response to interleukin-1
DI	0070742	molecular_function	C2H2 zinc finger domain binding
DI	0070761	cellular_component	pre-snoRNP complex
DI	0071339	cellular_component	MLL1 complex
DI	0140297	molecular_function	DNA-binding transcription factor binding
DI	1902166	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Dj	0000124	cellular_component	SAGA complex
Dj	0001701	biological_process	in utero embryonic development
Dj	0001756	biological_process	somitogenesis
Dj	0001892	biological_process	embryonic placenta development
Dj	0003677	molecular_function	DNA binding
Dj	0004402	molecular_function	histone acetyltransferase activity
Dj	0005515	molecular_function	protein binding
Dj	0005634	cellular_component	nucleus
Dj	0005654	cellular_component	nucleoplasm
Dj	0005669	cellular_component	transcription factor TFIID complex
Dj	0005737	cellular_component	cytoplasm
Dj	0006282	biological_process	regulation of DNA repair
Dj	0006338	biological_process	chromatin remodeling
Dj	0006351	biological_process	DNA-templated transcription
Dj	0006352	biological_process	DNA-templated transcription initiation
Dj	0006355	biological_process	regulation of DNA-templated transcription
Dj	0006357	biological_process	regulation of transcription by RNA polymerase II
Dj	0006366	biological_process	transcription by RNA polymerase II
Dj	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Dj	0010467	biological_process	gene expression
Dj	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Dj	0019899	molecular_function	enzyme binding
Dj	0030331	molecular_function	nuclear estrogen receptor binding
Dj	0033276	cellular_component	transcription factor TFTC complex
Dj	0036285	biological_process	SAGA complex assembly
Dj	0042789	biological_process	mRNA transcription by RNA polymerase II
Dj	0042802	molecular_function	identical protein binding
Dj	0043484	biological_process	regulation of RNA splicing
Dj	0045893	biological_process	positive regulation of DNA-templated transcription
Dj	0048371	biological_process	lateral mesodermal cell differentiation
Dj	0048471	cellular_component	perinuclear region of cytoplasm
Dj	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Dj	0060173	biological_process	limb development
Dj	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Dj	0070063	molecular_function	RNA polymerase binding
Dj	0097550	cellular_component	transcription preinitiation complex
Dj	1905069	biological_process	allantois development
Dj	1990841	molecular_function	promoter-specific chromatin binding
DJ	0000124	cellular_component	SAGA complex
DJ	0001701	biological_process	in utero embryonic development
DJ	0001756	biological_process	somitogenesis
DJ	0001892	biological_process	embryonic placenta development
DJ	0003677	molecular_function	DNA binding
DJ	0004402	molecular_function	histone acetyltransferase activity
DJ	0005515	molecular_function	protein binding
DJ	0005634	cellular_component	nucleus
DJ	0005654	cellular_component	nucleoplasm
DJ	0005669	cellular_component	transcription factor TFIID complex
DJ	0005737	cellular_component	cytoplasm
DJ	0006282	biological_process	regulation of DNA repair
DJ	0006338	biological_process	chromatin remodeling
DJ	0006351	biological_process	DNA-templated transcription
DJ	0006352	biological_process	DNA-templated transcription initiation
DJ	0006355	biological_process	regulation of DNA-templated transcription
DJ	0006357	biological_process	regulation of transcription by RNA polymerase II
DJ	0006366	biological_process	transcription by RNA polymerase II
DJ	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DJ	0010467	biological_process	gene expression
DJ	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DJ	0019899	molecular_function	enzyme binding
DJ	0030331	molecular_function	nuclear estrogen receptor binding
DJ	0033276	cellular_component	transcription factor TFTC complex
DJ	0036285	biological_process	SAGA complex assembly
DJ	0042789	biological_process	mRNA transcription by RNA polymerase II
DJ	0042802	molecular_function	identical protein binding
DJ	0043484	biological_process	regulation of RNA splicing
DJ	0045893	biological_process	positive regulation of DNA-templated transcription
DJ	0048371	biological_process	lateral mesodermal cell differentiation
DJ	0048471	cellular_component	perinuclear region of cytoplasm
DJ	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DJ	0060173	biological_process	limb development
DJ	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DJ	0070063	molecular_function	RNA polymerase binding
DJ	0097550	cellular_component	transcription preinitiation complex
DJ	1905069	biological_process	allantois development
DJ	1990841	molecular_function	promoter-specific chromatin binding
Dk	0003713	molecular_function	transcription coactivator activity
Dk	0005515	molecular_function	protein binding
Dk	0005634	cellular_component	nucleus
Dk	0005654	cellular_component	nucleoplasm
Dk	0005669	cellular_component	transcription factor TFIID complex
Dk	0006351	biological_process	DNA-templated transcription
Dk	0006366	biological_process	transcription by RNA polymerase II
Dk	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Dk	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Dk	0017025	molecular_function	TBP-class protein binding
Dk	0042789	biological_process	mRNA transcription by RNA polymerase II
Dk	0042809	molecular_function	nuclear vitamin D receptor binding
Dk	0043923	biological_process	host-mediated activation of viral transcription
Dk	0046966	molecular_function	nuclear thyroid hormone receptor binding
Dk	0046982	molecular_function	protein heterodimerization activity
Dk	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Dk	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Dl	0000124	cellular_component	SAGA complex
Dl	0003677	molecular_function	DNA binding
Dl	0003713	molecular_function	transcription coactivator activity
Dl	0005515	molecular_function	protein binding
Dl	0005634	cellular_component	nucleus
Dl	0005654	cellular_component	nucleoplasm
Dl	0005669	cellular_component	transcription factor TFIID complex
Dl	0006282	biological_process	regulation of DNA repair
Dl	0006351	biological_process	DNA-templated transcription
Dl	0006352	biological_process	DNA-templated transcription initiation
Dl	0006355	biological_process	regulation of DNA-templated transcription
Dl	0006357	biological_process	regulation of transcription by RNA polymerase II
Dl	0006366	biological_process	transcription by RNA polymerase II
Dl	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Dl	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Dl	0017025	molecular_function	TBP-class protein binding
Dl	0033276	cellular_component	transcription factor TFTC complex
Dl	0042789	biological_process	mRNA transcription by RNA polymerase II
Dl	0043484	biological_process	regulation of RNA splicing
Dl	0045893	biological_process	positive regulation of DNA-templated transcription
Dl	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Dl	0046982	molecular_function	protein heterodimerization activity
Dl	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Dl	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
Dl	0140297	molecular_function	DNA-binding transcription factor binding
DL	0000124	cellular_component	SAGA complex
DL	0003677	molecular_function	DNA binding
DL	0003713	molecular_function	transcription coactivator activity
DL	0005515	molecular_function	protein binding
DL	0005634	cellular_component	nucleus
DL	0005654	cellular_component	nucleoplasm
DL	0005669	cellular_component	transcription factor TFIID complex
DL	0006282	biological_process	regulation of DNA repair
DL	0006351	biological_process	DNA-templated transcription
DL	0006352	biological_process	DNA-templated transcription initiation
DL	0006355	biological_process	regulation of DNA-templated transcription
DL	0006357	biological_process	regulation of transcription by RNA polymerase II
DL	0006366	biological_process	transcription by RNA polymerase II
DL	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DL	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DL	0017025	molecular_function	TBP-class protein binding
DL	0033276	cellular_component	transcription factor TFTC complex
DL	0042789	biological_process	mRNA transcription by RNA polymerase II
DL	0043484	biological_process	regulation of RNA splicing
DL	0045893	biological_process	positive regulation of DNA-templated transcription
DL	0045944	biological_process	positive regulation of transcription by RNA polymerase II
DL	0046982	molecular_function	protein heterodimerization activity
DL	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DL	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DL	0140297	molecular_function	DNA-binding transcription factor binding
Dm	0003677	molecular_function	DNA binding
Dm	0005515	molecular_function	protein binding
Dm	0005634	cellular_component	nucleus
Dm	0005654	cellular_component	nucleoplasm
Dm	0005669	cellular_component	transcription factor TFIID complex
Dm	0005730	cellular_component	nucleolus
Dm	0006351	biological_process	DNA-templated transcription
Dm	0006352	biological_process	DNA-templated transcription initiation
Dm	0006366	biological_process	transcription by RNA polymerase II
Dm	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Dm	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Dm	0017025	molecular_function	TBP-class protein binding
Dm	0042789	biological_process	mRNA transcription by RNA polymerase II
Dm	0046982	molecular_function	protein heterodimerization activity
Dm	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Dm	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DO	0001091	molecular_function	RNA polymerase II general transcription initiation factor binding
DO	0005515	molecular_function	protein binding
DO	0005634	cellular_component	nucleus
DO	0005654	cellular_component	nucleoplasm
DO	0005669	cellular_component	transcription factor TFIID complex
DO	0005672	cellular_component	transcription factor TFIIA complex
DO	0006351	biological_process	DNA-templated transcription
DO	0006366	biological_process	transcription by RNA polymerase II
DO	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DO	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DO	0017025	molecular_function	TBP-class protein binding
DO	0042803	molecular_function	protein homodimerization activity
DO	0045944	biological_process	positive regulation of transcription by RNA polymerase II
DO	0046982	molecular_function	protein heterodimerization activity
DO	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DO	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DO	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
DP	0000785	cellular_component	chromatin
DP	0000791	cellular_component	euchromatin
DP	0000976	molecular_function	transcription cis-regulatory region binding
DP	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
DP	0000995	molecular_function	RNA polymerase III general transcription initiation factor activity
DP	0001046	molecular_function	core promoter sequence-specific DNA binding
DP	0001091	molecular_function	RNA polymerase II general transcription initiation factor binding
DP	0001093	molecular_function	TFIIB-class transcription factor binding
DP	0001164	molecular_function	RNA polymerase I core promoter sequence-specific DNA binding
DP	0001188	biological_process	RNA polymerase I preinitiation complex assembly
DP	0001939	cellular_component	female pronucleus
DP	0001940	cellular_component	male pronucleus
DP	0003677	molecular_function	DNA binding
DP	0005515	molecular_function	protein binding
DP	0005634	cellular_component	nucleus
DP	0005654	cellular_component	nucleoplasm
DP	0005668	cellular_component	RNA polymerase transcription factor SL1 complex
DP	0005669	cellular_component	transcription factor TFIID complex
DP	0005672	cellular_component	transcription factor TFIIA complex
DP	0005737	cellular_component	cytoplasm
DP	0006351	biological_process	DNA-templated transcription
DP	0006352	biological_process	DNA-templated transcription initiation
DP	0006355	biological_process	regulation of DNA-templated transcription
DP	0006366	biological_process	transcription by RNA polymerase II
DP	0006367	biological_process	transcription initiation at RNA polymerase II promoter
DP	0006383	biological_process	transcription by RNA polymerase III
DP	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
DP	0017162	molecular_function	aryl hydrocarbon receptor binding
DP	0019899	molecular_function	enzyme binding
DP	0032991	cellular_component	protein-containing complex
DP	0042789	biological_process	mRNA transcription by RNA polymerase II
DP	0045120	cellular_component	pronucleus
DP	0045945	biological_process	positive regulation of transcription by RNA polymerase III
DP	0051123	biological_process	RNA polymerase II preinitiation complex assembly
DP	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
DP	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
DP	0140297	molecular_function	DNA-binding transcription factor binding
DQ	0005672	cellular_component	transcription factor TFIIA complex
DQ	0006367	biological_process	transcription initiation at RNA polymerase II promoter
e	0003779	molecular_function	actin binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005737	cellular_component	cytoplasm
e	0005856	cellular_component	cytoskeleton
e	0006351	biological_process	DNA-templated transcription
e	0016020	cellular_component	membrane
e	0016592	cellular_component	mediator complex
e	0030864	cellular_component	cortical actin cytoskeleton
e	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
e	0051123	biological_process	RNA polymerase II preinitiation complex assembly
e	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
EA	0005515	molecular_function	protein binding
EA	0005634	cellular_component	nucleus
EA	0005654	cellular_component	nucleoplasm
EA	0005669	cellular_component	transcription factor TFIID complex
EA	0005673	cellular_component	transcription factor TFIIE complex
EA	0006351	biological_process	DNA-templated transcription
EA	0006366	biological_process	transcription by RNA polymerase II
EA	0006367	biological_process	transcription initiation at RNA polymerase II promoter
EA	0008270	molecular_function	zinc ion binding
EA	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
EA	0046872	molecular_function	metal ion binding
EA	0051123	biological_process	RNA polymerase II preinitiation complex assembly
EB	0001097	molecular_function	TFIIH-class transcription factor complex binding
EB	0003677	molecular_function	DNA binding
EB	0003723	molecular_function	RNA binding
EB	0005515	molecular_function	protein binding
EB	0005634	cellular_component	nucleus
EB	0005654	cellular_component	nucleoplasm
EB	0005669	cellular_component	transcription factor TFIID complex
EB	0005673	cellular_component	transcription factor TFIIE complex
EB	0005829	cellular_component	cytosol
EB	0006351	biological_process	DNA-templated transcription
EB	0006366	biological_process	transcription by RNA polymerase II
EB	0006367	biological_process	transcription initiation at RNA polymerase II promoter
EB	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
EB	0051123	biological_process	RNA polymerase II preinitiation complex assembly
f	0001223	molecular_function	transcription coactivator binding
f	0003677	molecular_function	DNA binding
f	0003712	molecular_function	transcription coregulator activity
f	0003713	molecular_function	transcription coactivator activity
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0006351	biological_process	DNA-templated transcription
f	0006357	biological_process	regulation of transcription by RNA polymerase II
f	0016020	cellular_component	membrane
f	0016592	cellular_component	mediator complex
f	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
f	0045944	biological_process	positive regulation of transcription by RNA polymerase II
f	0051123	biological_process	RNA polymerase II preinitiation complex assembly
f	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
f	0070847	cellular_component	core mediator complex
FA	0001091	molecular_function	RNA polymerase II general transcription initiation factor binding
FA	0001096	molecular_function	TFIIF-class transcription factor complex binding
FA	0003677	molecular_function	DNA binding
FA	0003723	molecular_function	RNA binding
FA	0005515	molecular_function	protein binding
FA	0005634	cellular_component	nucleus
FA	0005654	cellular_component	nucleoplasm
FA	0005669	cellular_component	transcription factor TFIID complex
FA	0005674	cellular_component	transcription factor TFIIF complex
FA	0006351	biological_process	DNA-templated transcription
FA	0006366	biological_process	transcription by RNA polymerase II
FA	0006367	biological_process	transcription initiation at RNA polymerase II promoter
FA	0006368	biological_process	transcription elongation by RNA polymerase II
FA	0009615	biological_process	response to virus
FA	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
FA	0019211	molecular_function	phosphatase activator activity
FA	0019903	molecular_function	protein phosphatase binding
FA	0019904	molecular_function	protein domain specific binding
FA	0032091	biological_process	negative regulation of protein binding
FA	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
FA	0032991	cellular_component	protein-containing complex
FA	0045944	biological_process	positive regulation of transcription by RNA polymerase II
FA	1990841	molecular_function	promoter-specific chromatin binding
FB	0003677	molecular_function	DNA binding
FB	0005515	molecular_function	protein binding
FB	0005634	cellular_component	nucleus
FB	0005654	cellular_component	nucleoplasm
FB	0005674	cellular_component	transcription factor TFIIF complex
FB	0006351	biological_process	DNA-templated transcription
FB	0006366	biological_process	transcription by RNA polymerase II
FB	0006367	biological_process	transcription initiation at RNA polymerase II promoter
FB	0006368	biological_process	transcription elongation by RNA polymerase II
FB	0015630	cellular_component	microtubule cytoskeleton
FB	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
FB	0016591	cellular_component	RNA polymerase II, holoenzyme
FB	0045944	biological_process	positive regulation of transcription by RNA polymerase II
FB	0090575	cellular_component	RNA polymerase II transcription regulator complex
g	0000151	cellular_component	ubiquitin ligase complex
g	0003712	molecular_function	transcription coregulator activity
g	0003713	molecular_function	transcription coactivator activity
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005667	cellular_component	transcription regulator complex
g	0006351	biological_process	DNA-templated transcription
g	0006357	biological_process	regulation of transcription by RNA polymerase II
g	0006367	biological_process	transcription initiation at RNA polymerase II promoter
g	0016567	biological_process	protein ubiquitination
g	0016592	cellular_component	mediator complex
g	0016604	cellular_component	nuclear body
g	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
g	0051123	biological_process	RNA polymerase II preinitiation complex assembly
g	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
g	0061630	molecular_function	ubiquitin protein ligase activity
h	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
h	0003712	molecular_function	transcription coregulator activity
h	0005515	molecular_function	protein binding
h	0005634	cellular_component	nucleus
h	0005654	cellular_component	nucleoplasm
h	0006351	biological_process	DNA-templated transcription
h	0006357	biological_process	regulation of transcription by RNA polymerase II
h	0016567	biological_process	protein ubiquitination
h	0016592	cellular_component	mediator complex
h	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
h	0051123	biological_process	RNA polymerase II preinitiation complex assembly
h	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
h	0070847	cellular_component	core mediator complex
i	0003712	molecular_function	transcription coregulator activity
i	0005515	molecular_function	protein binding
i	0005634	cellular_component	nucleus
i	0005654	cellular_component	nucleoplasm
i	0006351	biological_process	DNA-templated transcription
i	0006357	biological_process	regulation of transcription by RNA polymerase II
i	0016592	cellular_component	mediator complex
i	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
i	0051123	biological_process	RNA polymerase II preinitiation complex assembly
i	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
j	0000151	cellular_component	ubiquitin ligase complex
j	0003712	molecular_function	transcription coregulator activity
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0005654	cellular_component	nucleoplasm
j	0006351	biological_process	DNA-templated transcription
j	0006357	biological_process	regulation of transcription by RNA polymerase II
j	0016567	biological_process	protein ubiquitination
j	0016592	cellular_component	mediator complex
j	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
j	0051123	biological_process	RNA polymerase II preinitiation complex assembly
j	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
j	0061630	molecular_function	ubiquitin protein ligase activity
k	0000151	cellular_component	ubiquitin ligase complex
k	0003712	molecular_function	transcription coregulator activity
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005654	cellular_component	nucleoplasm
k	0006351	biological_process	DNA-templated transcription
k	0006357	biological_process	regulation of transcription by RNA polymerase II
k	0016567	biological_process	protein ubiquitination
k	0016592	cellular_component	mediator complex
k	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
k	0051123	biological_process	RNA polymerase II preinitiation complex assembly
k	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
k	0061630	molecular_function	ubiquitin protein ligase activity
l	0000151	cellular_component	ubiquitin ligase complex
l	0003712	molecular_function	transcription coregulator activity
l	0003713	molecular_function	transcription coactivator activity
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0005654	cellular_component	nucleoplasm
l	0006351	biological_process	DNA-templated transcription
l	0016567	biological_process	protein ubiquitination
l	0016592	cellular_component	mediator complex
l	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
l	0042809	molecular_function	nuclear vitamin D receptor binding
l	0045893	biological_process	positive regulation of DNA-templated transcription
l	0046966	molecular_function	nuclear thyroid hormone receptor binding
l	0051123	biological_process	RNA polymerase II preinitiation complex assembly
l	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
l	0061630	molecular_function	ubiquitin protein ligase activity
m	0000151	cellular_component	ubiquitin ligase complex
m	0003712	molecular_function	transcription coregulator activity
m	0005634	cellular_component	nucleus
m	0005654	cellular_component	nucleoplasm
m	0006351	biological_process	DNA-templated transcription
m	0006355	biological_process	regulation of DNA-templated transcription
m	0006357	biological_process	regulation of transcription by RNA polymerase II
m	0016567	biological_process	protein ubiquitination
m	0016592	cellular_component	mediator complex
m	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
m	0051123	biological_process	RNA polymerase II preinitiation complex assembly
m	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
m	0061630	molecular_function	ubiquitin protein ligase activity
m	0070847	cellular_component	core mediator complex
n	0003712	molecular_function	transcription coregulator activity
n	0003713	molecular_function	transcription coactivator activity
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005654	cellular_component	nucleoplasm
n	0006351	biological_process	DNA-templated transcription
n	0006357	biological_process	regulation of transcription by RNA polymerase II
n	0016020	cellular_component	membrane
n	0016592	cellular_component	mediator complex
n	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
n	0042809	molecular_function	nuclear vitamin D receptor binding
n	0045893	biological_process	positive regulation of DNA-templated transcription
n	0045944	biological_process	positive regulation of transcription by RNA polymerase II
n	0051123	biological_process	RNA polymerase II preinitiation complex assembly
n	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
n	0070847	cellular_component	core mediator complex
o	0003712	molecular_function	transcription coregulator activity
o	0005515	molecular_function	protein binding
o	0005634	cellular_component	nucleus
o	0005654	cellular_component	nucleoplasm
o	0005737	cellular_component	cytoplasm
o	0006351	biological_process	DNA-templated transcription
o	0006355	biological_process	regulation of DNA-templated transcription
o	0016020	cellular_component	membrane
o	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
o	0051123	biological_process	RNA polymerase II preinitiation complex assembly
o	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
o	0070847	cellular_component	core mediator complex
p	0003713	molecular_function	transcription coactivator activity
p	0005634	cellular_component	nucleus
p	0005654	cellular_component	nucleoplasm
p	0006351	biological_process	DNA-templated transcription
p	0006357	biological_process	regulation of transcription by RNA polymerase II
p	0006366	biological_process	transcription by RNA polymerase II
p	0016020	cellular_component	membrane
p	0016592	cellular_component	mediator complex
p	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
p	0042809	molecular_function	nuclear vitamin D receptor binding
p	0045893	biological_process	positive regulation of DNA-templated transcription
p	0046966	molecular_function	nuclear thyroid hormone receptor binding
p	0051123	biological_process	RNA polymerase II preinitiation complex assembly
p	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
PA	0003677	molecular_function	DNA binding
PA	0003899	molecular_function	DNA-directed RNA polymerase activity
PA	0006351	biological_process	DNA-templated transcription
PA	0006366	biological_process	transcription by RNA polymerase II
PB	0000428	cellular_component	DNA-directed RNA polymerase complex
PB	0001172	biological_process	RNA-templated transcription
PB	0003677	molecular_function	DNA binding
PB	0003899	molecular_function	DNA-directed RNA polymerase activity
PB	0003968	molecular_function	RNA-directed RNA polymerase activity
PB	0005634	cellular_component	nucleus
PB	0005654	cellular_component	nucleoplasm
PB	0006351	biological_process	DNA-templated transcription
PB	0008270	molecular_function	zinc ion binding
PB	0016740	molecular_function	transferase activity
PB	0016779	molecular_function	nucleotidyltransferase activity
PB	0016787	molecular_function	hydrolase activity
PB	0032549	molecular_function	ribonucleoside binding
PB	0046872	molecular_function	metal ion binding
PC	0000428	cellular_component	DNA-directed RNA polymerase complex
PC	0003677	molecular_function	DNA binding
PC	0003899	molecular_function	DNA-directed RNA polymerase activity
PC	0005634	cellular_component	nucleus
PC	0005654	cellular_component	nucleoplasm
PC	0005665	cellular_component	RNA polymerase II, core complex
PC	0006351	biological_process	DNA-templated transcription
PC	0006366	biological_process	transcription by RNA polymerase II
PC	0006367	biological_process	transcription initiation at RNA polymerase II promoter
PC	0006368	biological_process	transcription elongation by RNA polymerase II
PC	0046872	molecular_function	metal ion binding
PC	0046983	molecular_function	protein dimerization activity
PD	0000166	molecular_function	nucleotide binding
PD	0000428	cellular_component	DNA-directed RNA polymerase complex
PD	0005634	cellular_component	nucleus
PD	0005654	cellular_component	nucleoplasm
PD	0006352	biological_process	DNA-templated transcription initiation
PD	0030880	cellular_component	RNA polymerase complex
PE	0000428	cellular_component	DNA-directed RNA polymerase complex
PE	0003677	molecular_function	DNA binding
PE	0003899	molecular_function	DNA-directed RNA polymerase activity
PE	0005634	cellular_component	nucleus
PE	0005654	cellular_component	nucleoplasm
PE	0006351	biological_process	DNA-templated transcription
PF	0000428	cellular_component	DNA-directed RNA polymerase complex
PF	0001650	cellular_component	fibrillar center
PF	0003677	molecular_function	DNA binding
PF	0003899	molecular_function	DNA-directed RNA polymerase activity
PF	0005634	cellular_component	nucleus
PF	0005654	cellular_component	nucleoplasm
PF	0005665	cellular_component	RNA polymerase II, core complex
PF	0005666	cellular_component	RNA polymerase III complex
PF	0005736	cellular_component	RNA polymerase I complex
PF	0006351	biological_process	DNA-templated transcription
PF	0006360	biological_process	transcription by RNA polymerase I
PF	0006362	biological_process	transcription elongation by RNA polymerase I
PF	0006366	biological_process	transcription by RNA polymerase II
PF	0006367	biological_process	transcription initiation at RNA polymerase II promoter
PF	0006368	biological_process	transcription elongation by RNA polymerase II
PF	0006383	biological_process	transcription by RNA polymerase III
PF	0006384	biological_process	transcription initiation at RNA polymerase III promoter
PF	0006386	biological_process	termination of RNA polymerase III transcription
PF	0042797	biological_process	tRNA transcription by RNA polymerase III
PG	0000428	cellular_component	DNA-directed RNA polymerase complex
PG	0003676	molecular_function	nucleic acid binding
PG	0005634	cellular_component	nucleus
PG	0006351	biological_process	DNA-templated transcription
PG	0006352	biological_process	DNA-templated transcription initiation
PH	0000428	cellular_component	DNA-directed RNA polymerase complex
PH	0003899	molecular_function	DNA-directed RNA polymerase activity
PH	0005634	cellular_component	nucleus
PH	0005654	cellular_component	nucleoplasm
PH	0005665	cellular_component	RNA polymerase II, core complex
PH	0005666	cellular_component	RNA polymerase III complex
PH	0005736	cellular_component	RNA polymerase I complex
PH	0006351	biological_process	DNA-templated transcription
PI	0000428	cellular_component	DNA-directed RNA polymerase complex
PI	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
PI	0003676	molecular_function	nucleic acid binding
PI	0003899	molecular_function	DNA-directed RNA polymerase activity
PI	0005634	cellular_component	nucleus
PI	0005654	cellular_component	nucleoplasm
PI	0005665	cellular_component	RNA polymerase II, core complex
PI	0005730	cellular_component	nucleolus
PI	0006283	biological_process	transcription-coupled nucleotide-excision repair
PI	0006351	biological_process	DNA-templated transcription
PI	0006366	biological_process	transcription by RNA polymerase II
PI	0006367	biological_process	transcription initiation at RNA polymerase II promoter
PI	0006368	biological_process	transcription elongation by RNA polymerase II
PI	0008270	molecular_function	zinc ion binding
PI	0046872	molecular_function	metal ion binding
PJ	0003677	molecular_function	DNA binding
PJ	0003899	molecular_function	DNA-directed RNA polymerase activity
PJ	0006351	biological_process	DNA-templated transcription
PJ	0008270	molecular_function	zinc ion binding
PK	0000428	cellular_component	DNA-directed RNA polymerase complex
PK	0003677	molecular_function	DNA binding
PK	0003899	molecular_function	DNA-directed RNA polymerase activity
PK	0005634	cellular_component	nucleus
PK	0005665	cellular_component	RNA polymerase II, core complex
PK	0006351	biological_process	DNA-templated transcription
PK	0006366	biological_process	transcription by RNA polymerase II
PK	0046983	molecular_function	protein dimerization activity
PL	0000428	cellular_component	DNA-directed RNA polymerase complex
PL	0001650	cellular_component	fibrillar center
PL	0003677	molecular_function	DNA binding
PL	0003899	molecular_function	DNA-directed RNA polymerase activity
PL	0005634	cellular_component	nucleus
PL	0005654	cellular_component	nucleoplasm
PL	0005665	cellular_component	RNA polymerase II, core complex
PL	0005666	cellular_component	RNA polymerase III complex
PL	0005730	cellular_component	nucleolus
PL	0005736	cellular_component	RNA polymerase I complex
PL	0006351	biological_process	DNA-templated transcription
PL	0006362	biological_process	transcription elongation by RNA polymerase I
PL	0006366	biological_process	transcription by RNA polymerase II
PL	0006367	biological_process	transcription initiation at RNA polymerase II promoter
PL	0006368	biological_process	transcription elongation by RNA polymerase II
PL	0006383	biological_process	transcription by RNA polymerase III
PL	0006384	biological_process	transcription initiation at RNA polymerase III promoter
PL	0006386	biological_process	termination of RNA polymerase III transcription
PL	0008270	molecular_function	zinc ion binding
PL	0046872	molecular_function	metal ion binding
q	0000151	cellular_component	ubiquitin ligase complex
q	0003712	molecular_function	transcription coregulator activity
q	0003713	molecular_function	transcription coactivator activity
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005654	cellular_component	nucleoplasm
q	0005667	cellular_component	transcription regulator complex
q	0006351	biological_process	DNA-templated transcription
q	0006357	biological_process	regulation of transcription by RNA polymerase II
q	0006367	biological_process	transcription initiation at RNA polymerase II promoter
q	0016020	cellular_component	membrane
q	0016567	biological_process	protein ubiquitination
q	0016592	cellular_component	mediator complex
q	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
q	0042809	molecular_function	nuclear vitamin D receptor binding
q	0045893	biological_process	positive regulation of DNA-templated transcription
q	0045944	biological_process	positive regulation of transcription by RNA polymerase II
q	0046966	molecular_function	nuclear thyroid hormone receptor binding
q	0051123	biological_process	RNA polymerase II preinitiation complex assembly
q	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
q	0061630	molecular_function	ubiquitin protein ligase activity
q	0070847	cellular_component	core mediator complex
r	0003712	molecular_function	transcription coregulator activity
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005654	cellular_component	nucleoplasm
r	0006351	biological_process	DNA-templated transcription
r	0006357	biological_process	regulation of transcription by RNA polymerase II
r	0016592	cellular_component	mediator complex
r	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
r	0051123	biological_process	RNA polymerase II preinitiation complex assembly
r	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
r	0070847	cellular_component	core mediator complex
s	0003712	molecular_function	transcription coregulator activity
s	0005515	molecular_function	protein binding
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0006351	biological_process	DNA-templated transcription
s	0006357	biological_process	regulation of transcription by RNA polymerase II
s	0016592	cellular_component	mediator complex
s	0016604	cellular_component	nuclear body
s	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
s	0045944	biological_process	positive regulation of transcription by RNA polymerase II
s	0051123	biological_process	RNA polymerase II preinitiation complex assembly
s	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
t	0003712	molecular_function	transcription coregulator activity
t	0003713	molecular_function	transcription coactivator activity
t	0003899	molecular_function	DNA-directed RNA polymerase activity
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005654	cellular_component	nucleoplasm
t	0006351	biological_process	DNA-templated transcription
t	0006357	biological_process	regulation of transcription by RNA polymerase II
t	0006366	biological_process	transcription by RNA polymerase II
t	0016592	cellular_component	mediator complex
t	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
t	0032991	cellular_component	protein-containing complex
t	0051123	biological_process	RNA polymerase II preinitiation complex assembly
t	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
u	0000151	cellular_component	ubiquitin ligase complex
u	0003712	molecular_function	transcription coregulator activity
u	0003713	molecular_function	transcription coactivator activity
u	0003899	molecular_function	DNA-directed RNA polymerase activity
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0006351	biological_process	DNA-templated transcription
u	0006357	biological_process	regulation of transcription by RNA polymerase II
u	0016567	biological_process	protein ubiquitination
u	0016592	cellular_component	mediator complex
u	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
u	0045944	biological_process	positive regulation of transcription by RNA polymerase II
u	0051123	biological_process	RNA polymerase II preinitiation complex assembly
u	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
u	0061630	molecular_function	ubiquitin protein ligase activity
v	0003712	molecular_function	transcription coregulator activity
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005737	cellular_component	cytoplasm
v	0006351	biological_process	DNA-templated transcription
v	0006357	biological_process	regulation of transcription by RNA polymerase II
v	0016592	cellular_component	mediator complex
v	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
v	0051123	biological_process	RNA polymerase II preinitiation complex assembly
v	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
w	0003713	molecular_function	transcription coactivator activity
w	0005515	molecular_function	protein binding
w	0005634	cellular_component	nucleus
w	0005654	cellular_component	nucleoplasm
w	0005667	cellular_component	transcription regulator complex
w	0006351	biological_process	DNA-templated transcription
w	0006355	biological_process	regulation of DNA-templated transcription
w	0006357	biological_process	regulation of transcription by RNA polymerase II
w	0006367	biological_process	transcription initiation at RNA polymerase II promoter
w	0010628	biological_process	positive regulation of gene expression
w	0016592	cellular_component	mediator complex
w	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
w	0051123	biological_process	RNA polymerase II preinitiation complex assembly
w	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
x	0003712	molecular_function	transcription coregulator activity
x	0003713	molecular_function	transcription coactivator activity
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0006351	biological_process	DNA-templated transcription
x	0016592	cellular_component	mediator complex
x	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
x	0042809	molecular_function	nuclear vitamin D receptor binding
x	0045893	biological_process	positive regulation of DNA-templated transcription
x	0046966	molecular_function	nuclear thyroid hormone receptor binding
x	0051123	biological_process	RNA polymerase II preinitiation complex assembly
x	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
z	0003712	molecular_function	transcription coregulator activity
z	0003713	molecular_function	transcription coactivator activity
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0006351	biological_process	DNA-templated transcription
z	0006357	biological_process	regulation of transcription by RNA polymerase II
z	0006367	biological_process	transcription initiation at RNA polymerase II promoter
z	0010628	biological_process	positive regulation of gene expression
z	0016592	cellular_component	mediator complex
z	0032968	biological_process	positive regulation of transcription elongation by RNA polymerase II
z	0051123	biological_process	RNA polymerase II preinitiation complex assembly
z	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
z	0070847	cellular_component	core mediator complex

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. SSGMKSSSGLGSSGSL

Chain	Residue	Details
a	SER1240-LEU1255

---

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DNDPSDYVEqdDI

Chain	Residue	Details
PC	ASP136-ILE148

---

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cav..CqnvFcvdcdvfvHdsl..H

Chain	Residue	Details
2	CYS360-HIS380

---

site_id	PS00107
Number of Residues	25
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGQFATVYkArdkntnqiv.........AIKK

Chain	Residue	Details
8	LEU18-LYS42

---

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IlHrDLKpnNLLL

Chain	Residue	Details
8	ILE133-LEU145

---

site_id	PS00115
Number of Residues	7
Details	RNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPA

Chain	Residue	Details
PA	TYR1593-ALA1599
PA	TYR1671-SER1677
PA	TYR1678-SER1684
PA	TYR1685-SER1691
PA	TYR1692-SER1698
PA	TYR1699-SER1705
PA	TYR1706-SER1712
PA	TYR1713-SER1719
PA	TYR1720-SER1726
PA	TYR1727-SER1733
PA	TYR1734-SER1740
PA	TYR1615-SER1621
PA	TYR1741-ASN1747
PA	TYR1748-ASN1754
PA	TYR1755-SER1761
PA	TYR1762-SER1768
PA	TYR1769-ASN1775
PA	TYR1776-ASN1782
PA	TYR1783-SER1789
PA	TYR1790-SER1796
PA	TYR1797-SER1803
PA	TYR1818-SER1824
PA	TYR1622-SER1628
PA	TYR1825-SER1831
PA	TYR1839-SER1845
PA	TYR1853-LYS1859
PA	TYR1860-LYS1866
PA	TYR1867-LYS1873
PA	TYR1874-THR1880
PA	TYR1888-THR1894
PA	TYR1902-LYS1908
PA	TYR1909-THR1915
PA	TYR1916-LYS1922
PA	TYR1629-SER1635
PA	TYR1923-THR1929
PA	TYR1930-LYS1936
PA	TYR1947-THR1953
PA	TYR1636-SER1642
PA	TYR1643-SER1649
PA	TYR1650-SER1656
PA	TYR1657-SER1663
PA	TYR1664-SER1670

---

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH

Chain	Residue	Details
PI	TYR112-HIS118

---

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV

Chain	Residue	Details
DP	TYR192-VAL241
DP	TYR283-LEU332

---

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP

Chain	Residue	Details
PC	ASN32-PRO72

---

site_id	PS00466
Number of Residues	38
Details	ZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW

Chain	Residue	Details
PI	CYS86-TRP123

---

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CgHtLCesCV

Chain	Residue	Details
0	CYS26-VAL35

---

site_id	PS00627
Number of Residues	12
Details	GHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. MKsSsGLGSSGS

Chain	Residue	Details
a	MET1243-SER1254

---

site_id	PS00633
Number of Residues	58
Details	BROMODOMAIN_1 Bromodomain signature. TypFhtpvNakvvk..DYYkiItrpMdlqtLrenvrkrl..Ypsreefrehlel.IvkNSatY

Chain	Residue	Details
DA	THR1402-TYR1459
DA	SER1525-TYR1582

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGsaDrTVRLWDV

Chain	Residue	Details
DE	VAL642-VAL656
DE	LEU684-ILE698
DE	LEU726-ALA740

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. AvVVFDEAHN

Chain	Residue	Details
7	ALA229-ASN238

---

site_id	PS00782
Number of Residues	16
Details	TFIIB Transcription factor TFIIB repeat signature. GRandAIASACLYIAC

Chain	Residue	Details
BA	GLY153-CYS168
BA	GLY247-SER262

---

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPEHvvMtkEE

Chain	Residue	Details
PE	HIS142-GLU155

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARvLGtRAlQ

Chain	Residue	Details
PF	THR58-GLN72

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG

Chain	Residue	Details
PJ	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. InkEdHTLgNiIksqLlkdpqVlfagYkvpHP

Chain	Residue	Details
PK	ILE35-PRO66

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT

Chain	Residue	Details
PB	GLY932-THR944

---

site_id	PS01359
Number of Residues	45
Details	ZF_PHD_1 Zinc finger PHD-type signature. CpgCnkpddgspm....................................IgCdd..Cddw.YHwpCvgimtappeemq.................................WfCpkC

Chain	Residue	Details
Dc	CYS868-CYS912

---

site_id	PS01030
Number of Residues	27
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCQECNNMLypkedkenrillyaCrnC

Chain	Residue	Details
PI	PHE16-CYS42

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	160
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	9
Details	Region: {"description":"Interaction with the Elongin BC complex"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	43
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	Motif: {"description":"LXXLL motif 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	19
Details	Domain: {"description":"UIM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00213","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	44
Details	Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15530371","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15530371","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by CDK1 and CDK2","evidences":[{"source":"PubMed","id":"11113184","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9832506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by CDK2","evidences":[{"source":"PubMed","id":"11113184","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15530371","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9832506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by CDK8","evidences":[{"source":"PubMed","id":"10993082","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9DBA9","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	176
Details	Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	34
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"A0JN27","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	437
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	160
Details	Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	3
Details	Motif: {"description":"DEVH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33902107","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7NVV","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7NVX","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33902107","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7NVV","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7NVX","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	199
Details	Region: {"description":"Mediates interaction with MMS19"}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	3
Details	Motif: {"description":"DEAH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	13
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31253769","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RO4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	53
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27193682","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IY6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D902","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	43
Details	Region: {"description":"Minimal region required to interact with TAF12","evidences":[{"source":"PubMed","id":"10594036","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	78
Details	Repeat: {"description":"WD 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	78
Details	Repeat: {"description":"WD 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	82
Details	Repeat: {"description":"WD 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	82
Details	Repeat: {"description":"WD 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	78
Details	Repeat: {"description":"WD 5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	39
Details	Repeat: {"description":"WD 6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI46
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q63801","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI47
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q63801","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI48
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q63801","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI49
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI50
Number of Residues	67
Details	Domain: {"description":"Histone-fold; involved in forming hexamer structure in TFIID complex","evidences":[{"source":"PubMed","id":"33795473","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI51
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI52
Number of Residues	1
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine; alternate","evidences":[{"source":"PubMed","id":"15099517","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16415881","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25959397","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI53
Number of Residues	177
Details	Domain: {"description":"Histone-fold","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI54
Number of Residues	152
Details	Repeat: {"description":"1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI55
Number of Residues	153
Details	Repeat: {"description":"2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI56
Number of Residues	17
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27193682","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IYD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI57
Number of Residues	4
Details	Region: {"description":"Core promoter DNA-binding","evidences":[{"source":"PubMed","id":"10619841","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI58
Number of Residues	72
Details	Region: {"description":"Necessary for TATA box-bound TBP complex formation","evidences":[{"source":"PubMed","id":"8515820","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8516311","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI59
Number of Residues	3
Details	Region: {"description":"Core promoter DNA-binding","evidences":[{"source":"PubMed","id":"7675079","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI60
Number of Residues	3
Details	Region: {"description":"Core promoter DNA-binding","evidences":[{"source":"PubMed","id":"10619841","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7675079","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI61
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00469","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11045620","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14641108","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27193682","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DL6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RLY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IY6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI62
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00469","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11045620","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14641108","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DL6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RLY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI63
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine; by autocatalysis","evidences":[{"source":"PubMed","id":"12931194","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI64
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI65
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI75
Number of Residues	42
Details	Zinc finger: {"description":"TFIIS-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI76
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI77
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI79
Number of Residues	4
Details	Motif: {"description":"LXXLL motif 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI80
Number of Residues	4
Details	Motif: {"description":"LXXLL motif 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI81
Number of Residues	4
Details	Motif: {"description":"LXXLL motif 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI82
Number of Residues	4
Details	Motif: {"description":"LXXLL motif 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI83
Number of Residues	50
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI84
Number of Residues	47
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI85
Number of Residues	45
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI86
Number of Residues	37
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI87
Number of Residues	53
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---