7LBM

Structure of the human Mediator-bound transcription pre-initiation complex

This is a non-PDB format compatible entry.

Summary for 7LBM

• Entry DOI: 10.2210/pdb7lbm/pdb
• EMDB information: 23255
• Descriptor: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, ... (59 entities in total)
• Functional Keywords: pre-initiation complex, mediator, initiation, complex, transcription, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 56
• Total formula weight: 2509244.44

Authors

Abdella, R.,Talyzina, A.,He, Y. (deposition date: 2021-01-08, release date: 2021-03-24, Last modification date: 2021-04-14)

• Primary citation: Abdella, R.,Talyzina, A.,Chen, S.,Inouye, C.J.,Tjian, R.,He, Y.; Structure of the human Mediator-bound transcription preinitiation complex.; Science, 372:52-56, 2021; PubMed: 33707221; DOI: 10.1126/science.abg3074

Experimental method

ELECTRON MICROSCOPY (4.8 Å)