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PDB: 162 results

7A1V
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BU of 7a1v by Molmil
Crystal structure of YTHDF2 in complex with m1A
Descriptor: 6-AMINO-1-METHYLPURINE, GLYCEROL, SULFATE ION, ...
Authors:Wang, X, Caflisch, A.
Deposit date:2020-08-14
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of YTHDF2 in complex with m1A
To Be Published
6FPP
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BU of 6fpp by Molmil
Structure of S. pombe Mmi1
Descriptor: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
4U8T
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BU of 4u8t by Molmil
Crystal structure of YTH domain of Zygosaccharomyces rouxii MRB1 protein in complex with N6-Methyladenosine RNA
Descriptor: RNA (5'-R(*AP*GP*GP*(6MZ)P*CP*AP*U)-3'), ZYRO0G01672p
Authors:Luo, S, Tong, L.
Deposit date:2014-08-04
Release date:2014-09-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain.
Proc.Natl.Acad.Sci.USA, 111, 2014
4WQN
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BU of 4wqn by Molmil
Crystal structure of N6-methyladenosine RNA reader YTHDF2
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, YTH domain-containing family protein 2
Authors:Zhu, T, Roundtree, I.A, Wang, P, Wang, X, Wang, L, Sun, C, Tian, Y, Li, J, He, C, Xu, Y.
Deposit date:2014-10-22
Release date:2014-11-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.121 Å)
Cite:Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.
Cell Res., 24, 2014
5O8M
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BU of 5o8m by Molmil
Crystal structure of the MmI1 YTH domain
Descriptor: GLYCEROL, YTH domain-containing protein mmi1
Authors:Brettschneider, J, Verdel, A, Kadlec, J.
Deposit date:2017-06-13
Release date:2018-04-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.
EMBO J., 36, 2017
7BIK
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BU of 7bik by Molmil
Crystal structure of YTHDF2 in complex with m6Am
Descriptor: (2~{R},3~{S},4~{R},5~{R})-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol, GLYCEROL, SULFATE ION, ...
Authors:Wang, X, Caflisch, A.
Deposit date:2021-01-12
Release date:2021-11-24
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of YTHDF2 in complex with m6Am
To Be Published
5ZUU
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BU of 5zuu by Molmil
Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA
Descriptor: 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Wu, B, Nie, H, Li, S, Patel, D.J.
Deposit date:2018-05-08
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis.
Mol Plant, 2021
8K2E
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BU of 8k2e by Molmil
Crystal structure of YTHDC1 and Y3 complex
Descriptor: 2-chloranyl-6-(4-fluoranylphenoxy)benzoic acid, SULFATE ION, YTH domain-containing protein 1
Authors:Zhang, H.L, Yang, S.Y.
Deposit date:2023-07-12
Release date:2024-07-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:PocketFlow is a data-and-knowledge-driven structure-based molecular generative model
Nat. Mach. Intell., 6, 2024
2MTV
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BU of 2mtv by Molmil
Solution Structure of the YTH Domain of YT521-B in complex with N6-Methyladenosine containing RNA
Descriptor: RNA_(5'-R(*UP*GP*(6MZ)P*CP*AP*C)-3'), YTH domain-containing protein 1
Authors:Theler, D, Dominguez, C, Blatter, M, Boudet, J, Allain, F.H.-T.
Deposit date:2014-09-01
Release date:2014-11-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA.
Nucleic Acids Res., 42, 2014
4RCI
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BU of 4rci by Molmil
Crystal structure of YTHDF1 YTH domain
Descriptor: UNKNOWN ATOM OR ION, YTH domain-containing family protein 1
Authors:Xu, C, Tempel, W, Liu, K, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-09-16
Release date:2014-10-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
J.Biol.Chem., 290, 2015
4R3I
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BU of 4r3i by Molmil
The crystal structure of an RNA complex
Descriptor: RNA (5'-R(*GP*GP*(6MZ)P*CP*U)-3'), UNKNOWN ATOM OR ION, YTH domain-containing protein 1
Authors:Tempel, W, Xu, C, Liu, K, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-08-15
Release date:2014-09-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
Nat.Chem.Biol., 10, 2014
2YUD
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BU of 2yud by Molmil
Solution structure of the YTH domain in YTH domain-containing protein 1 (Putative splicing factor YT521)
Descriptor: YTH domain-containing protein 1
Authors:He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-06
Release date:2007-10-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the YTH domain in YTH domain-containing protein 1 (Putative splicing factor YT521)
To be Published
6FPQ
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BU of 6fpq by Molmil
Structure of S. pombe Mmi1 in complex with 7-mer RNA
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
2YU6
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BU of 2yu6 by Molmil
Solution structure of the YTH domain in YTH domain-containing protein 2
Descriptor: YTH domain-containing protein 2
Authors:Endo, R, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2007-10-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the YTH domain in YTH domain-containing protein 2
To be Published
5H8A
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BU of 5h8a by Molmil
Mmi1 YTH domain
Descriptor: YTH domain-containing protein mmi1
Authors:Chatterjee, D, Goldgur, Y, Shuman, S.
Deposit date:2015-12-23
Release date:2016-01-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast.
Rna, 22, 2016
9H36
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BU of 9h36 by Molmil
Crystal structure of the YTHDC2 YTH domain
Descriptor: 3'-5' RNA helicase YTHDC2
Authors:Bedi, R.K, Caflisch, A.
Deposit date:2024-10-15
Release date:2024-10-30
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Crystal structure of the YTHDC2 YTH domain
To Be Published
9H35
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BU of 9h35 by Molmil
Crystal structure of the YTHDC2 YTH domain
Descriptor: 3'-5' RNA helicase YTHDC2
Authors:Bedi, R.K, Caflisch, A.
Deposit date:2024-10-15
Release date:2024-10-30
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Crystal structure of the YTHDC2 YTH domain
To Be Published
5HFZ
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BU of 5hfz by Molmil
Mmi1 YTH domain
Descriptor: YTH domain-containing protein mmi1
Authors:Chatterjee, D, Goldgur, Y, Shuman, S.
Deposit date:2016-01-07
Release date:2016-02-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast.
Rna, 22, 2016
6FPX
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BU of 6fpx by Molmil
Structure of S. pombe Mmi1 in complex with 11-mer RNA
Descriptor: GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-12
Release date:2018-05-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6RT5
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BU of 6rt5 by Molmil
The YTH domain of YTHDC1 protein in complex with Gm6AC oligonucleotide
Descriptor: RNA (5'-R(*(6MZ)P*C)-3'), SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R, Sledz, P, Caflisch, A.
Deposit date:2019-05-22
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif.
J Chem Theory Comput, 15, 2019
6RT4
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BU of 6rt4 by Molmil
The YTH domain of YTHDC1 protein in complex with m6ACU oligonucleotide
Descriptor: RNA (5'-R(*(6MZ)P*C)-3'), SULFATE ION, YTH domain-containing protein 1
Authors:Bedi, R, Sledz, P, Caflisch, A.
Deposit date:2019-05-22
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif.
J Chem Theory Comput, 15, 2019
6K6U
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BU of 6k6u by Molmil
Crystal structure of the human YTHDC2 YTH domain
Descriptor: 3'-5' RNA helicase YTHDC2
Authors:Ma, C, Liao, S, Xu, C.
Deposit date:2019-06-04
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human YTHDC2 YTH domain.
Biochem.Biophys.Res.Commun., 518, 2019
6LR2
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BU of 6lr2 by Molmil
SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-2 CONTAINING PROTEIN 2
Descriptor: YTH domain containing protein 2 (YTHDC2)
Authors:Muto, Y, Kobayashi, N, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2020-01-15
Release date:2021-01-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-CONTAINING PROTEIN 2
TO BE PUBLISHED
7L4X
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BU of 7l4x by Molmil
YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by two six-bp DNA duplexes in P3221 Crystal
Descriptor: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA w/N6A
Authors:Horton, J.R, Cheng, X.
Deposit date:2020-12-21
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
7L4Y
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BU of 7l4y by Molmil
YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by Two Six-bp DNA Duplexes in P212121 Crystal
Descriptor: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA 13mer
Authors:Horton, J.R, Cheng, X.
Deposit date:2020-12-21
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021

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