3NHE
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![BU of 3nhe by Molmil](/molmil-images/mine/3nhe) | |
6SQO
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![BU of 6sqo by Molmil](/molmil-images/mine/6sqo) | Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | Deposit date: | 2019-09-04 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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7F0N
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8GLP
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![BU of 8glp by Molmil](/molmil-images/mine/8glp) | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-03-22 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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6SQS
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![BU of 6sqs by Molmil](/molmil-images/mine/6sqs) | Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub | Descriptor: | E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | Deposit date: | 2019-09-04 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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8QOI
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![BU of 8qoi by Molmil](/molmil-images/mine/8qoi) | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | Descriptor: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | Authors: | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | Deposit date: | 2023-09-29 | Release date: | 2024-06-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (1.9 Å) | Cite: | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Nat.Struct.Mol.Biol., 2024
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5WVO
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![BU of 5wvo by Molmil](/molmil-images/mine/5wvo) | Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3 | Descriptor: | DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ... | Authors: | Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K. | Deposit date: | 2016-12-28 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance Mol. Cell, 68, 2017
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3PHW
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![BU of 3phw by Molmil](/molmil-images/mine/3phw) | OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with Ubiquitin | Descriptor: | ETHANAMINE, RNA-directed RNA polymerase L, Ubiquitin-40S ribosomal protein S27a | Authors: | Akutsu, M, Ye, Y, Virdee, S, Komander, D. | Deposit date: | 2010-11-04 | Release date: | 2011-02-02 | Last modified: | 2014-08-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains. Proc.Natl.Acad.Sci.USA, 108, 2011
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7R4X
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![BU of 7r4x by Molmil](/molmil-images/mine/7r4x) | Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Pellegrino, S, Dent, K.C, Spikes, T, Warren, A.J. | Deposit date: | 2022-02-09 | Release date: | 2023-02-22 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Cryo-EM reconstruction of the human 40S ribosomal subunit at 2.15 angstrom resolution. Nucleic Acids Res., 51, 2023
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8HTF
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![BU of 8htf by Molmil](/molmil-images/mine/8htf) | Crystal structure of an effector in complex with ubiquitin | Descriptor: | NAD(+)--protein-threonine ADP-ribosyltransferase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Ubiquitin-40S ribosomal protein S27a (Fragment) | Authors: | Tan, J, Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs. Nat.Chem.Biol., 20, 2024
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6SQR
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![BU of 6sqr by Molmil](/molmil-images/mine/6sqr) | Crystal structure of Cat MDM2-S429E RING domain bound to UbcH5B-Ub | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | Authors: | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | Deposit date: | 2019-09-04 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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3AXC
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![BU of 3axc by Molmil](/molmil-images/mine/3axc) | Crystal structure of linear diubiquitin | Descriptor: | GLYCEROL, Ubiquitin | Authors: | Rohaim, A, Kawasaki, M, Kato, R, Dikic, I, Wakatsuki, S. | Deposit date: | 2011-04-01 | Release date: | 2012-01-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structure of a compact conformation of linear diubiquitin Acta Crystallogr.,Sect.D, 68, 2012
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3NOB
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![BU of 3nob by Molmil](/molmil-images/mine/3nob) | |
8HTC
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![BU of 8htc by Molmil](/molmil-images/mine/8htc) | Crystal structure of a SeMet-labeled effector from Chromobacterium violaceum in complex with Ubiquitin | Descriptor: | NAD(+)--protein-threonine ADP-ribosyltransferase, Ubiquitin-40S ribosomal protein S27a (Fragment) | Authors: | Tan, J, Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs. Nat.Chem.Biol., 20, 2024
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4R62
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![BU of 4r62 by Molmil](/molmil-images/mine/4r62) | Structure of Rad6~Ub | Descriptor: | ACETATE ION, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 2 | Authors: | Kumar, P, Wolberger, C. | Deposit date: | 2014-08-22 | Release date: | 2015-09-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. Nucleic Acids Res., 43, 2015
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8G5Y
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![BU of 8g5y by Molmil](/molmil-images/mine/8g5y) | mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.29 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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6KG6
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![BU of 6kg6 by Molmil](/molmil-images/mine/6kg6) | Crystal structure of MavC/UBE2N-Ub complex | Descriptor: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | Authors: | Wang, Y, Huang, Y, Chang, M, Feng, Y. | Deposit date: | 2019-07-10 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC. Nat Commun, 11, 2020
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7XNY
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![BU of 7xny by Molmil](/molmil-images/mine/7xny) | |
5YDK
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![BU of 5ydk by Molmil](/molmil-images/mine/5ydk) | Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, tetrameric form | Descriptor: | E3 ubiquitin-protein ligase RNF168, GLYCEROL, Ubiquitin-40S ribosomal protein S27a | Authors: | Takahashi, T.S, Sato, Y, Fukai, S. | Deposit date: | 2017-09-13 | Release date: | 2018-03-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.505 Å) | Cite: | Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168 Nat Commun, 9, 2018
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8G60
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![BU of 8g60 by Molmil](/molmil-images/mine/8g60) | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | Descriptor: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | Authors: | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | Deposit date: | 2023-02-14 | Release date: | 2023-04-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8IFE
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![BU of 8ife by Molmil](/molmil-images/mine/8ife) | Arbekacin-added human 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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8IFD
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![BU of 8ifd by Molmil](/molmil-images/mine/8ifd) | Dibekacin-added human 80S ribosome | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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7OOJ
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![BU of 7ooj by Molmil](/molmil-images/mine/7ooj) | Structure of D-Thr53 Ubiquitin | Descriptor: | CADMIUM ION, Ubiquitin | Authors: | Becker, S. | Deposit date: | 2021-05-27 | Release date: | 2022-05-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A litmus test for classifying recognition mechanisms of transiently binding proteins. Nat Commun, 13, 2022
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8T4S
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6ZMI
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![BU of 6zmi by Molmil](/molmil-images/mine/6zmi) | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-02 | Release date: | 2020-08-19 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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