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PDB: 21 results

6S9K
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BU of 6s9k by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 peptide containing 14-3-3 binding motif Ser139 and NLS
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, Caspase-2
Authors:Alblova, M, Obsil, T, Obsilova, V.
Deposit date:2019-07-15
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
6ZBT
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BU of 6zbt by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser342
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
Authors:Joshi, R, Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2020-06-09
Release date:2021-07-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.79948521 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
3UZD
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BU of 3uzd by Molmil
Crystal structure of 14-3-3 GAMMA
Descriptor: 14-3-3 protein gamma, Histone deacetylase 4, MAGNESIUM ION, ...
Authors:Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-07
Release date:2012-03-21
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
6ZC9
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BU of 6zc9 by Molmil
Structure of 14-3-3 gamma in complex with Nedd4-2 14-3-3 binding motif Ser448
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, E3 ubiquitin-protein ligase NEDD4-like
Authors:Pohl, P, Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2020-06-10
Release date:2021-07-21
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.89895988 Å)
Cite:14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.
Commun Biol, 4, 2021
6A5S
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BU of 6a5s by Molmil
Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif
Descriptor: 14-3-3 protein gamma, MAGNESIUM ION, SODIUM ION, ...
Authors:Xu, Y, Ren, J.Q, Feng, W.
Deposit date:2018-06-25
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization.
Autophagy, 15, 2019
4E2E
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BU of 4e2e by Molmil
Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein gamma
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2012-03-08
Release date:2012-03-21
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activa tion protein, gamma polypeptide (YWHAG) from Homo sapiens at 2.25 A resolution
To be published
7A6Y
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BU of 7a6y by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide stabilized by FC-A
Descriptor: 14-3-3 protein gamma, DAPK2 C-terminal peptide, FUSICOCCIN
Authors:Horvath, M, Obsilova, V, Obsil, T.
Deposit date:2020-08-27
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
2B05
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BU of 2b05 by Molmil
Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide
Descriptor: 14-3-3 protein gamma, peptide
Authors:Papagrigoriou, E, Elkins, J, Arrowsmith, C, Zhao, Y, Debreczeni, E.J, Edwards, A, Weigelt, J, Doyle, D, von Delft, F, Turnbull, A, Yang, X.
Deposit date:2005-09-13
Release date:2005-10-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of 14-3-3 gamma in complex with a phosphoserine peptide
TO BE PUBLISHED
6GKF
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BU of 6gkf by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser139
Descriptor: 14-3-3 protein gamma, Caspase-2
Authors:Alblova, M, Obsil, T, Obsilova, V.
Deposit date:2018-05-20
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:14-3-3 protein masks the nuclear localization sequence of caspase-2.
FEBS J., 285, 2018
6BZD
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BU of 6bzd by Molmil
Structure of 14-3-3 gamma R57E mutant bound to GlcNAcylated peptide
Descriptor: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, GlcNAcylated peptide
Authors:Schumacher, M.A.
Deposit date:2017-12-22
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7A6R
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BU of 7a6r by Molmil
Structure of 14-3-3 gamma in complex with DAPK2 peptide containing the 14-3-3 binding motif
Descriptor: 14-3-3 protein gamma, DAPK2 C-terminal peptide
Authors:Horvath, M, Obsilova, V, Obsil, T.
Deposit date:2020-08-26
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:14-3-3 proteins inactivate DAPK2 by promoting its dimerization and protecting key regulatory phosphosites.
Commun Biol, 4, 2021
5D3E
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BU of 5d3e by Molmil
Crystal structure of human 14-3-3 gamma in complex with CFTR R-domain peptide pS768-pS795
Descriptor: 14-3-3 protein gamma, Cystic fibrosis transmembrane conductance regulator
Authors:Stevers, L.M, Leysen, S.F.R, Ottmann, C.
Deposit date:2015-08-06
Release date:2016-03-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.
Proc.Natl.Acad.Sci.USA, 113, 2016
6SAD
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BU of 6sad by Molmil
Structure of 14-3-3 gamma in complex with double phosphorylated caspase-2 peptide on Ser139 and Ser164
Descriptor: 14-3-3 protein gamma, Caspase-2
Authors:Kalabova, D, Obsil, T, Obsilova, V.
Deposit date:2019-07-16
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
6FEL
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BU of 6fel by Molmil
Structure of 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser511
Descriptor: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2018-01-02
Release date:2018-01-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).
Biochim. Biophys. Acta, 1862, 2018
6GKG
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BU of 6gkg by Molmil
Structure of 14-3-3 gamma in complex with caspase-2 14-3-3 binding motif Ser164
Descriptor: 14-3-3 protein gamma, Caspase-2
Authors:Alblova, M, Obsil, T, Obsilova, V.
Deposit date:2018-05-20
Release date:2018-10-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:14-3-3 protein masks the nuclear localization sequence of caspase-2.
FEBS J., 285, 2018
6BYJ
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BU of 6byj by Molmil
Structure of human 14-3-3 gamma bound to O-GlcNAc peptide
Descriptor: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSTTATPPVSQASSTTTSTW O-GlcNac peptide
Authors:Schumacher, M.A.
Deposit date:2017-12-20
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc.Natl.Acad.Sci.USA, 115, 2018
4O46
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BU of 4o46 by Molmil
14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228
Descriptor: 14-3-3 protein gamma, Nonstructural protein 1, UNKNOWN ATOM OR ION, ...
Authors:Qin, S, Liu, Y, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
6Y4K
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BU of 6y4k by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and Fusicoccin A
Descriptor: 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2, FUSICOCCIN
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2020-02-21
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
4J6S
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BU of 4j6s by Molmil
14-3-3gamma complexed with the N-terminal sequence of tyrosine hydroxylase (residues 1-43)
Descriptor: 14-3-3 protein gamma, N-terminal motif of tyrosine hydroxylase
Authors:Mileni, M, Martinez, A, Stevens, R.C.
Deposit date:2013-02-11
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes.
J.Mol.Biol., 426, 2014
6Y6B
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BU of 6y6b by Molmil
Crystal structure of human 14-3-3 gamma in complex with CaMKK2 14-3-3 binding motif Ser100 and 16-OMe-Fusicoccin H
Descriptor: (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[[(1~{S},3~{R},6~{S},7~{S},8~{R},9~{R},10~{R},11~{R},14~{S})-14-(me thoxymethyl)-3,10-dimethyl-9-oxidanyl-6-propan-2-yl-8-tricyclo[9.3.0.0^{3,7}]tetradecanyl]oxy]oxane-3,4,5-triol, 14-3-3 protein gamma, Calcium/calmodulin-dependent protein kinase kinase 2
Authors:Lentini Santo, D, Obsilova, V, Obsil, T.
Deposit date:2020-02-26
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins.
Acs Chem.Biol., 15, 2020
6BYL
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BU of 6byl by Molmil
Structure of 14-3-3 gamma bound to O-GlcNAcylated thr peptide
Descriptor: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSASTTVPVTTATTTTTSTW O-GlcNac peptide
Authors:Schumacher, M.A.
Deposit date:2017-12-20
Release date:2018-05-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.
Proc.Natl.Acad.Sci.USA, 115, 2018

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PDB entries from 2024-07-03

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