Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 88 results

1PB7
DownloadVisualize
BU of 1pb7 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION
Descriptor: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1Y20
DownloadVisualize
BU of 1y20 by Molmil
Crystal structure of the NR1 ligand-binding core in complex with ACPC
Descriptor: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
Authors:Inanobe, A, Gouaux, E.
Deposit date:2004-11-19
Release date:2005-07-12
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors.
Neuron, 47, 2005
1PB8
DownloadVisualize
BU of 1pb8 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION
Descriptor: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1Y1Z
DownloadVisualize
BU of 1y1z by Molmil
Crystal structure of the NR1 ligand binding core in complex with ACBC
Descriptor: 1-AMINOCYCLOBUTANECARBOXLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
Authors:Inanobe, A, Gouaux, E.
Deposit date:2004-11-19
Release date:2005-07-12
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors.
Neuron, 47, 2005
5U8C
DownloadVisualize
BU of 5u8c by Molmil
CRYSTAL STRUCTURE OF GLUN1/GLUN2A LIGAND-BINDING DOMAIN IN COMPLEX WITH GLYCINE AND NVP-AAM077
Descriptor: GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A, GLYCEROL, ...
Authors:Romero-Hernandez, A, Furukawa, H.
Deposit date:2016-12-14
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077.
Mol. Pharmacol., 92, 2017
1PB9
DownloadVisualize
BU of 1pb9 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION
Descriptor: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
6UZ6
DownloadVisualize
BU of 6uz6 by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and glutamate
Descriptor: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-14
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
5I57
DownloadVisualize
BU of 5i57 by Molmil
Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains
Descriptor: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Mou, T.-C, Sprang, S.R, Hansen, K.B.
Deposit date:2016-02-14
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.
Neuron, 91, 2016
1Y1M
DownloadVisualize
BU of 1y1m by Molmil
Crystal structure of the NR1 ligand binding core in complex with cycloleucine
Descriptor: 1-AMINOCYCLOPENTANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1
Authors:Inanobe, A, Gouaux, E.
Deposit date:2004-11-18
Release date:2005-07-12
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors.
Neuron, 47, 2005
4NF8
DownloadVisualize
BU of 4nf8 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and glutamate in PEG2000MME
Descriptor: GLUTAMIC ACID, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Jespersen, A, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.856 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
6UZR
DownloadVisualize
BU of 6uzr by Molmil
Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and homoquinolinic acid
Descriptor: 3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCEROL, GLYCINE, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-15
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
4KCC
DownloadVisualize
BU of 4kcc by Molmil
Crystal Structure of the NMDA Receptor GluN1 Ligand Binding Domain Apo State
Descriptor: Glutamate receptor ionotropic, NMDA 1, PHOSPHATE ION
Authors:Berger, A.J, Lau, A.Y, Mayer, M.L.
Deposit date:2013-04-24
Release date:2013-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:Conformational Analysis of NMDA Receptor GluN1, GluN2, and GluN3 Ligand-Binding Domains Reveals Subtype-Specific Characteristics.
Structure, 21, 2013
1PBQ
DownloadVisualize
BU of 1pbq by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION
Descriptor: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-07-29
Last modified:2020-07-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
2HQW
DownloadVisualize
BU of 2hqw by Molmil
Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide
Descriptor: CALCIUM ION, Calmodulin, Glutamate NMDA receptor subunit zeta 1
Authors:Akyol, Z, Gakhar, L, Sorensen, B.R, Hell, J.H, Shea, M.A.
Deposit date:2006-07-19
Release date:2007-11-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains.
Structure, 15, 2007
4NF5
DownloadVisualize
BU of 4nf5 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and D-AP5
Descriptor: 5-phosphono-D-norvaline, GLYCEROL, GLYCINE, ...
Authors:Jespersen, A, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
6UZG
DownloadVisualize
BU of 6uzg by Molmil
Crystal structure of GLUN1/GLUN2A-4M mutant ligand-binding domain in complex with glycine and homoquinolinic acid
Descriptor: 3-(carboxymethyl)pyridine-2-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-15
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020
5VII
DownloadVisualize
BU of 5vii by Molmil
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-(3-fluoropropyl)phenyl-ACEPC
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-[(2R)-2-amino-2-carboxyethyl]-1-[4-(3-fluoropropyl)phenyl]-1H-pyrazole-3-carboxylic acid, DI(HYDROXYETHYL)ETHER, ...
Authors:Mou, T.-C, Conti, P, Pinto, A, Tamborini, L, Sprang, S.R, Hansen, K.B.
Deposit date:2017-04-16
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6OVE
DownloadVisualize
BU of 6ove by Molmil
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-propylphenyl-ACEPC
Descriptor: (3R,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(4-propylphenyl)pyrazolidine-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Syrenne, J.T, Mou, T.C, Tamborini, L, Pinto, A, Sprang, S.R, Hansen, K.B.
Deposit date:2019-05-07
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-ACEPC
To Be Published
4NF4
DownloadVisualize
BU of 4nf4 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with DCKA and glutamate
Descriptor: 4-hydroxy-5,7-dimethylquinoline-2-carboxylic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ...
Authors:Annie, J, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
2A5T
DownloadVisualize
BU of 2a5t by Molmil
Crystal Structure Of The NR1/NR2A ligand-binding cores complex
Descriptor: GLUTAMIC ACID, GLYCINE, N-methyl-D-aspartate receptor NMDAR1-4a subunit, ...
Authors:Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E.
Deposit date:2005-06-30
Release date:2005-11-15
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Subunit arrangement and function in NMDA receptors
Nature, 438, 2005
6USU
DownloadVisualize
BU of 6usu by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with L689,560 and glutamate
Descriptor: (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ...
Authors:Romero-Hernandez, A, Tajima, N, Chou, T, Furukawa, H.
Deposit date:2019-10-28
Release date:2020-07-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:Structural Basis of Functional Transitions in Mammalian NMDA Receptors.
Cell, 182, 2020
4NF6
DownloadVisualize
BU of 4nf6 by Molmil
Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and PPDA
Descriptor: (2S,3R)-1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Jespersen, A, Tajima, N, Furukawa, H.
Deposit date:2013-10-30
Release date:2014-03-12
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
6OVD
DownloadVisualize
BU of 6ovd by Molmil
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-ACEPC
Descriptor: (3S,5S)-5-[(2R)-2-amino-2-carboxyethyl]-1-(3-ethylphenyl)pyrazolidine-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Syrenne, J.T, Mou, T.C, Tamborini, L, Pinto, A, Sprang, S.R, Hansen, K.B.
Deposit date:2019-05-07
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-ACEPC
To Be Published
5VIJ
DownloadVisualize
BU of 5vij by Molmil
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-bromophenyl-ACEPC
Descriptor: 5-[(2R)-2-amino-2-carboxyethyl]-1-(4-bromophenyl)-1H-pyrazole-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Mou, T.-C, Conti, P, Pinto, A, Tamborini, L, Sprang, S.R, Hansen, K.B.
Deposit date:2017-04-16
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6UZW
DownloadVisualize
BU of 6uzw by Molmil
Crystal structure of GLUN1/GLUN2A ligand-binding domain in complex with glycine and UBP791
Descriptor: (2S,3R)-1-[7-(2-carboxyethyl)phenanthrene-2-carbonyl]piperazine-2,3-dicarboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
Authors:Wang, J.X, Furukawa, H.
Deposit date:2019-11-15
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors.
Nat Commun, 11, 2020

 

1234>

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon