5U8C
CRYSTAL STRUCTURE OF GLUN1/GLUN2A LIGAND-BINDING DOMAIN IN COMPLEX WITH GLYCINE AND NVP-AAM077
Summary for 5U8C
| Entry DOI | 10.2210/pdb5u8c/pdb |
| Descriptor | Glutamate receptor ionotropic, NMDA 1, GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2A, GLYCINE, ... (6 entities in total) |
| Functional Keywords | receptor, glycine and nvp-aam077, transport protein |
| Biological source | Rattus norvegicus (Rat) More |
| Total number of polymer chains | 2 |
| Total formula weight | 65746.70 |
| Authors | Romero-Hernandez, A.,Furukawa, H. (deposition date: 2016-12-14, release date: 2017-05-17, Last modification date: 2023-10-04) |
| Primary citation | Romero-Hernandez, A.,Furukawa, H. Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077. Mol. Pharmacol., 92:22-29, 2017 Cited by PubMed: 28468946DOI: 10.1124/mol.116.107912 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.598 Å) |
Structure validation
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