5VII
Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-(3-fluoropropyl)phenyl-ACEPC
Replaces: 5DDXSummary for 5VII
Entry DOI | 10.2210/pdb5vii/pdb |
Related | 5VIH 5VIJ |
Descriptor | Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, GLYCINE, ... (7 entities in total) |
Functional Keywords | nmda receptor, antagonist, transport protein, receptor |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 2 |
Total formula weight | 65763.99 |
Authors | Mou, T.-C.,Conti, P.,Pinto, A.,Tamborini, L.,Sprang, S.R.,Hansen, K.B. (deposition date: 2017-04-16, release date: 2017-04-26, Last modification date: 2023-10-04) |
Primary citation | Lind, G.E.,Mou, T.C.,Tamborini, L.,Pomper, M.G.,De Micheli, C.,Conti, P.,Pinto, A.,Hansen, K.B. Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits. Proc. Natl. Acad. Sci. U.S.A., 114:E6942-E6951, 2017 Cited by PubMed: 28760974DOI: 10.1073/pnas.1707752114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.951 Å) |
Structure validation
Download full validation report