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PDB: 8 results
4RWF
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BU of 4rwf by Molmil
Crystal structure of the CLR:RAMP2 extracellular domain heterodimer with bound adrenomedullin
Descriptor: 1,2-ETHANEDIOL, Adrenomedullin, Maltose transporter subunit, ...
Authors:Booe, J, Pioszak, A.
Deposit date:2014-12-03
Release date:2015-05-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor.
Mol.Cell, 58, 2015
6V2E
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BU of 6v2e by Molmil
Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant
Descriptor: ADM, AMINO GROUP, FORMIC ACID, ...
Authors:Booe, J.M, Pioszak, A.A.
Deposit date:2019-11-22
Release date:2020-08-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors.
Acs Pharmacol Transl Sci, 3, 2020
6UUS
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CryoEM Structure of the active Adrenomedullin 2 receptor G protein complex with adrenomedullin peptide
Descriptor: ADM, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R.
Deposit date:2019-10-31
Release date:2020-04-01
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
Acs Pharmacol Transl Sci, 3, 2020
5V6Y
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Crystal structure of the human CLR:RAMP1 extracellular domain heterodimer with bound high-affinity and altered selectivity adrenomedullin variant
Descriptor: ADM, Maltose-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pioszak, A, Booe, J.
Deposit date:2017-03-17
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Probing the Mechanism of Receptor Activity-Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Peptide Antagonists.
Mol. Pharmacol., 93, 2018
6UUN
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BU of 6uun by Molmil
CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin peptide
Descriptor: ADM, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R.
Deposit date:2019-10-30
Release date:2020-03-25
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
Acs Pharmacol Transl Sci, 3, 2020
7VV0
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BU of 7vv0 by Molmil
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, local
Descriptor: CHOLESTEROL, Mas-related G-protein coupled receptor member X2, peptide from Pro-adrenomedullin
Authors:Li, Y, Yang, F.
Deposit date:2021-11-04
Release date:2021-12-01
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
2FLY
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BU of 2fly by Molmil
Proadrenomedullin N-Terminal 20 Peptide
Descriptor: Proadrenomedullin N-20 terminal peptide
Authors:Lucyk, S, Taha, H, Yamamoto, H, Miskolzie, M, Kotovych, G.
Deposit date:2006-01-06
Release date:2006-03-28
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth
Biopolymers, 81, 2006
2L7S
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BU of 2l7s by Molmil
Determination of the three-dimensional structure of adrenomedullin, a first step towards the analysis of its interactions with receptors and small molecules
Descriptor: Adrenomedullin
Authors:Jimenez-Barbero, J, Perez-Castells, J, Nieto, L.
Deposit date:2010-12-21
Release date:2011-09-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules.
Biopolymers, 97, 2012

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