7DFC
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![BU of 7dfc by Molmil](/molmil-images/mine/7dfc) | Crystal of Arrestin2-V2Rpp-3-Fab30 complex | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | Deposit date: | 2020-11-06 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nat Commun, 12, 2021
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7DFA
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![BU of 7dfa by Molmil](/molmil-images/mine/7dfa) | Crystal of Arrestin2-V2Rpp-4-Fab30 complex | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | Deposit date: | 2020-11-06 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nat Commun, 12, 2021
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4JQI
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![BU of 4jqi by Molmil](/molmil-images/mine/4jqi) | Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide | Descriptor: | 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ... | Authors: | Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J. | Deposit date: | 2013-03-20 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature, 497, 2013
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7DW9
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![BU of 7dw9 by Molmil](/molmil-images/mine/7dw9) | |
7KH0
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![BU of 7kh0 by Molmil](/molmil-images/mine/7kh0) | Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex | Descriptor: | Arg-vasopressin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, L, Xu, J, Gao, S, Sun, D, Liu, H, Liu, Z, Du, Y, Zhang, C. | Deposit date: | 2020-10-19 | Release date: | 2021-05-26 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structure of the AVP-vasopressin receptor 2-G s signaling complex. Cell Res., 31, 2021
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7DF9
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![BU of 7df9 by Molmil](/molmil-images/mine/7df9) | Crystal of Arrestin2-V2Rpp-1-Fab30 complex | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | Deposit date: | 2020-11-06 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nat Commun, 12, 2021
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8WU1
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![BU of 8wu1 by Molmil](/molmil-images/mine/8wu1) | Cryo-EM structure of CB1-beta-arrestin1 complex | Descriptor: | Beta-arrestin-1, Cannabinoid receptor 1,Vasopressin V2 receptor, Fab30 heavy chain, ... | Authors: | Liao, Y, Zhang, H, Shen, Q, Cai, C. | Deposit date: | 2023-10-19 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of CB1-beta-arrestin1 complex to be published
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7DFB
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![BU of 7dfb by Molmil](/molmil-images/mine/7dfb) | Crystal of Arrestin2-V2Rpp-6-7-Fab30 complex | Descriptor: | Beta-arrestin-1, FAB30 HEAVY CHAIN, FAB30 LIGHT CHAIN, ... | Authors: | Sun, J.P, Yu, X, Xiao, P, He, Q.T, Lin, J.Y, Zhu, Z.L. | Deposit date: | 2020-11-06 | Release date: | 2021-07-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.28 Å) | Cite: | Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2. Nat Commun, 12, 2021
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8JRV
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![BU of 8jrv by Molmil](/molmil-images/mine/8jrv) | Cryo-EM structure of the glucagon receptor bound to glucagon and beta-arrestin 1 | Descriptor: | Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), Glucagon, HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, ... | Authors: | Chen, K, Zhang, C, Lin, S, Zhao, Q, Wu, B. | Deposit date: | 2023-06-17 | Release date: | 2023-08-16 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Tail engagement of arrestin at the glucagon receptor. Nature, 620, 2023
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8JRU
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![BU of 8jru by Molmil](/molmil-images/mine/8jru) | Cryo-EM structure of the glucagon receptor bound to beta-arrestin 1 in ligand-free state | Descriptor: | Beta-arrestin 1 and single-chain fragment variable 30 (scFv30), HA signal peptide,HPC4 purification tag,Glucagon receptor,C-terminal tail of Vasopressin V2 receptor, Nanobody 32, ... | Authors: | Chen, K, Zhang, C, Lin, S, Zhao, Q, Wu, B. | Deposit date: | 2023-06-17 | Release date: | 2023-08-16 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Tail engagement of arrestin at the glucagon receptor. Nature, 620, 2023
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8WRZ
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![BU of 8wrz by Molmil](/molmil-images/mine/8wrz) | Cry-EM structure of cannabinoid receptor-arrestin 2 complex | Descriptor: | (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, Beta-arrestin-1, Soluble cytochrome b562,Cannabinoid receptor 1, ... | Authors: | Wang, Y.X, Wang, T, Wu, L.J, Hua, T, Liu, Z.J. | Deposit date: | 2023-10-16 | Release date: | 2024-02-28 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of cannabinoid receptor CB1-beta-arrestin complex. Protein Cell, 15, 2024
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8I10
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![BU of 8i10 by Molmil](/molmil-images/mine/8i10) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin V2 receptor, V2R (Local refine) | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-01-12 | Release date: | 2023-05-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83, 2023
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6NI2
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![BU of 6ni2 by Molmil](/molmil-images/mine/6ni2) | Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex | Descriptor: | Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J. | Deposit date: | 2018-12-26 | Release date: | 2019-11-20 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex. Nat.Struct.Mol.Biol., 26, 2019
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6U1N
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![BU of 6u1n by Molmil](/molmil-images/mine/6u1n) | GPCR-Beta arrestin structure in lipid bilayer | Descriptor: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, Beta-arrestin-1, Fab30 heavy chain, ... | Authors: | Staus, D.P, Hu, H, Robertson, M.J, Kleinhenz, A.L.W, Wingler, L.M, Capel, W.D, Latorraca, N.R, Lefkowitz, R.J, Skiniotis, G. | Deposit date: | 2019-08-16 | Release date: | 2020-02-26 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc. Nature, 579, 2020
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8GOC
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![BU of 8goc by Molmil](/molmil-images/mine/8goc) | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin V2 receptor, V2R | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-05-17 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Structural snapshots uncover a key phosphorylation motif in GPCRs driving beta-arrestin activation. Mol.Cell, 83, 2023
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7BB6
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![BU of 7bb6 by Molmil](/molmil-images/mine/7bb6) | AVP-V2R-Galphas-beta1-gamma2-Nb35 (L state) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Bous, J, Mouillac, B, Bron, P, Granier, S, Floquet, N, Leyrat, C. | Deposit date: | 2020-12-17 | Release date: | 2021-06-02 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex. Sci Adv, 7, 2021
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7R0J
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![BU of 7r0j by Molmil](/molmil-images/mine/7r0j) | Structure of the V2 receptor Cter-arrestin2-ScFv30 complex | Descriptor: | Arrestin2, ScFv30, V2R Cter | Authors: | Bous, J, Fouillen, A, Trapani, S, Granier, S, Mouillac, B, Bron, P. | Deposit date: | 2022-02-02 | Release date: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex. Sci Adv, 8, 2022
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7BB7
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![BU of 7bb7 by Molmil](/molmil-images/mine/7bb7) | AVP-V2R-Galphas-beta1-gamma2-Nb35(T state) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Bous, J, Mouillac, B, Bron, P, Granier, S, Floquet, N, Leyrat, C. | Deposit date: | 2020-12-17 | Release date: | 2021-06-02 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex. Sci Adv, 7, 2021
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7R0C
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![BU of 7r0c by Molmil](/molmil-images/mine/7r0c) | Structure of the AVP-V2R-arrestin2-ScFv30 complex | Descriptor: | AVP, Arrestin2, ScFv30, ... | Authors: | Bous, J, Fouillen, A, Trapani, S, Granier, S, Mouillac, B, Bron, P. | Deposit date: | 2022-02-01 | Release date: | 2022-09-14 | Method: | ELECTRON MICROSCOPY (4.73 Å) | Cite: | Structure of the vasopressin hormone-V2 receptor-beta-arrestin1 ternary complex. Sci Adv, 8, 2022
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