6WPQ
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![BU of 6wpq by Molmil](/molmil-images/mine/6wpq) | GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant | Descriptor: | Heterogeneous nuclear ribonucleoprotein A2 | Authors: | Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | Deposit date: | 2020-04-27 | Release date: | 2020-08-19 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. Nat Commun, 11, 2020
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7WM3
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![BU of 7wm3 by Molmil](/molmil-images/mine/7wm3) | hnRNP A2/B1 RRMs in complex with single-stranded DNA | Descriptor: | DNA (5'-D(P*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | Abula, A, Liu, Y, Guo, H, Li, T, Ji, X. | Deposit date: | 2022-01-14 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition. J.Mol.Biol., 435, 2022
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5HO4
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![BU of 5ho4 by Molmil](/molmil-images/mine/5ho4) | Crystal structure of hnRNPA2B1 in complex with 10-mer RNA | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3') | Authors: | Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B. | Deposit date: | 2016-01-19 | Release date: | 2017-02-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
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5WWG
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![BU of 5wwg by Molmil](/molmil-images/mine/5wwg) | Crystal structure of hnRNPA2B1 in complex with AAGGACUUGC | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3') | Authors: | Wu, B.X, Su, S.C, Ma, J.B. | Deposit date: | 2017-01-01 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
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5WWF
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![BU of 5wwf by Molmil](/molmil-images/mine/5wwf) | Crystal structure of hnRNPA2B1 in complex with RNA | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA | Authors: | Wu, B.X, Su, S.C, Ma, J.B. | Deposit date: | 2017-01-01 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
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5WWE
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![BU of 5wwe by Molmil](/molmil-images/mine/5wwe) | Crystal structure of hnRNPA2B1 in complex with RNA | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3') | Authors: | Wu, B.X, Su, S.C, Ma, J.B. | Deposit date: | 2017-01-01 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
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5EN1
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![BU of 5en1 by Molmil](/molmil-images/mine/5en1) | Crystal structure of hnRNPA2B1 in complex with RNA | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') | Authors: | Wu, B.X, Su, S.C, Ma, J.B. | Deposit date: | 2015-11-09 | Release date: | 2016-11-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 Nat Commun, 2018
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8HNI
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![BU of 8hni by Molmil](/molmil-images/mine/8hni) | hnRNP A2/B1 RRMs in complex with telomeric DNA | Descriptor: | DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3'), Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | Liu, Y, Abula, A, Xiao, H, Guo, H, Li, T, Zheng, L, Chen, B, Nguyen, H, Ji, X. | Deposit date: | 2022-12-07 | Release date: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.644 Å) | Cite: | Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition. J.Mol.Biol., 435, 2023
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6WQK
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![BU of 6wqk by Molmil](/molmil-images/mine/6wqk) | hnRNPA2 Low complexity domain (LCD) determined by cryoEM | Descriptor: | MCherry fluorescent protein,Heterogeneous nuclear ribonucleoproteins A2/B1 chimera | Authors: | Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | Deposit date: | 2020-04-29 | Release date: | 2020-08-26 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. Nat Commun, 11, 2020
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8DUW
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![BU of 8duw by Molmil](/molmil-images/mine/8duw) | HnRNPA2 D290V LCD PM2 | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | Deposit date: | 2022-07-27 | Release date: | 2023-08-02 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. J.Biol.Chem., 300, 2023
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8DU2
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![BU of 8du2 by Molmil](/molmil-images/mine/8du2) | HnRNPA2 D290V LCD PM1 | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | Deposit date: | 2022-07-26 | Release date: | 2023-08-02 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. J.Biol.Chem., 300, 2023
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8EC7
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![BU of 8ec7 by Molmil](/molmil-images/mine/8ec7) | HnRNPA2 D290V LCD PM3 | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | Deposit date: | 2022-09-01 | Release date: | 2023-09-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation. J.Biol.Chem., 300, 2023
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1X4B
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![BU of 1x4b by Molmil](/molmil-images/mine/1x4b) | Solution structure of RRM domain in Heterogeneous nuclear ribonucleaoproteins A2/B1 | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-14 | Release date: | 2005-11-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of RRM domain in Heterogeneous nuclear ribonucleaoproteins A2/B1 To be Published
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