3WDD
| |
3WDC
| |
3WDB
| |
6CN8
| High-resolution structure of ClpC1-NTD binding to Rufomycin-I | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpC1, CHLORIDE ION, PHOSPHATE ION, ... | Authors: | Abad-Zapatero, C, Wolf, N.W. | Deposit date: | 2018-03-07 | Release date: | 2019-06-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads. Acs Infect Dis., 5, 2019
|
|
3WDE
| |
8IBP
| |
6PBQ
| Structure of ClpC1-NTD | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATP-dependent Clp protease ATP-binding subunit ClpC1, PHOSPHATE ION | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-06-14 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
|
|
7AA4
| Structure of ClpC1-NTD bound to a CymA analogue | Descriptor: | Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue | Authors: | Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T. | Deposit date: | 2020-09-03 | Release date: | 2021-08-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | BacPROTACs mediate targeted protein degradation in bacteria. Cell, 185, 2022
|
|
6PBA
| Structure of ClpC1-NTD | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpC1 | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-06-13 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
|
|
8IBO
| |
8B9U
| |
6UCR
| Structure of ClpC1-NTD L92S L96P | Descriptor: | ACETATE ION, Negative regulator of genetic competence ClpC/mecB | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-09-17 | Release date: | 2020-05-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
|
|
6PBS
| Structure of ClpC1-NTD in complex with Ecumicin | Descriptor: | ACETATE ION, ATP-dependent Clp protease ATP-binding subunit ClpC1, ecumicin | Authors: | Abad-Zapatero, C, Wolf, N.M. | Deposit date: | 2019-06-14 | Release date: | 2020-05-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the N-terminal domain of ClpC1 in complex with the antituberculosis natural product ecumicin reveals unique binding interactions. Acta Crystallogr D Struct Biol, 76, 2020
|
|
8A8V
| Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Cyclomarin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
|
|
8A8U
| Mycobacterium tuberculosis ClpC1 hexamer structure | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
|
|
8A8W
| Mycobacterium tuberculosis ClpC1 hexamer structure bound to the natural product antibiotic Ecumycin (class 1) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpC1, Bound polypeptide | Authors: | Felix, J, Fraga, H, Gragera, M, Bueno, T, Weinhaeupl, K. | Deposit date: | 2022-06-24 | Release date: | 2022-10-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.29 Å) | Cite: | Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action. J.Biol.Chem., 298, 2022
|
|