8B9U

Structure of ClpC1 NTD from Mycobacterium tuberculosis

Summary for 8B9U

Entry DOI	10.2210/pdb8b9u/pdb
Descriptor	ATP-dependent Clp protease ATP-binding subunit ClpC1, (MLE)V(MAA)(E9M)G, FORMIC ACID, ... (4 entities in total)
Functional Keywords	ligand bound state, chaperone
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More
Total number of polymer chains	3
Total formula weight	32587.36
Authors	Meinhart, A.,Hoi, D.M.,Clausen, T. (deposition date: 2022-10-10, release date: 2023-07-05, Last modification date: 2024-02-07)
Primary citation	Hoi, D.M.,Junker, S.,Junk, L.,Schwechel, K.,Fischel, K.,Podlesainski, D.,Hawkins, P.M.E.,van Geelen, L.,Kaschani, F.,Leodolter, J.,Morreale, F.E.,Kleine, S.,Guha, S.,Rumpel, K.,Schmiedel, V.M.,Weinstabl, H.,Meinhart, A.,Payne, R.J.,Kaiser, M.,Hartl, M.,Boehmelt, G.,Kazmaier, U.,Kalscheuer, R.,Clausen, T. Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival. Cell, 186:2176-, 2023 Cited by PubMed: 37137307 DOI: 10.1016/j.cell.2023.04.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation