Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 70 results

4YOE
DownloadVisualize
BU of 4yoe by Molmil
Structure of UP1 bound to RNA 5'-AGU-3'
Descriptor: ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ...
Authors:Meagher, J.L, Stuckey, J.A.
Deposit date:2015-03-11
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein.
J.Mol.Biol., 427, 2015
5MPL
DownloadVisualize
BU of 5mpl by Molmil
hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UCAGUU
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
8RZV
DownloadVisualize
BU of 8rzv by Molmil
Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
Descriptor: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
Authors:Dunnett, L, Prischi, F.
Deposit date:2024-02-13
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA
To Be Published
6J60
DownloadVisualize
BU of 6j60 by Molmil
hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217)
Descriptor: 9-mer peptide (GFGGNDNFG) from Heterogeneous nuclear ribonucleoprotein A1
Authors:Luo, F, Zhou, H, Gui, X, Li, D, Li, X, Liu, C.
Deposit date:2019-01-12
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.96 Å)
Cite:Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
1L3K
DownloadVisualize
BU of 1l3k by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
Authors:Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M.
Deposit date:2002-02-27
Release date:2002-04-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
2UP1
DownloadVisualize
BU of 2up1 by Molmil
STRUCTURE OF UP1-TELOMERIC DNA COMPLEX
Descriptor: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1)
Authors:Ding, J, Hayashi, M.K, Krainer, A.R, Xu, R.-M.
Deposit date:1998-07-10
Release date:1999-11-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA.
Genes Dev., 13, 1999
1HA1
DownloadVisualize
BU of 1ha1 by Molmil
HNRNP A1 (RBD1,2) FROM HOMO SAPIENS
Descriptor: HNRNP A1
Authors:Shamoo, Y, Krueger, U, Rice, L, Williams, K.R, Steitz, T.A.
Deposit date:1996-10-30
Release date:1997-05-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the two RNA binding domains of human hnRNP A1 at 1.75 A resolution.
Nat.Struct.Biol., 4, 1997
7ZJ2
DownloadVisualize
BU of 7zj2 by Molmil
Amyloid fibril (in vitro) from full-length hnRNPA1 protein
Descriptor: Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1
Authors:Sharma, K, Banerjee, S, Schmidt, M, Faendrich, M.
Deposit date:2022-04-08
Release date:2023-08-02
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Cryo-EM Structure of the Full-length hnRNPA1 Amyloid Fibril.
J.Mol.Biol., 435, 2023
9F1S
DownloadVisualize
BU of 9f1s by Molmil
Structure of UP1 S4ES6E phosphomimetic mutant
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
Authors:Dunnett, L, Prischi, F.
Deposit date:2024-04-20
Release date:2024-05-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of UP1 S4ES6E phosphomimetic mutant
To Be Published
7BX7
DownloadVisualize
BU of 7bx7 by Molmil
Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain
Descriptor: Heterogeneous nuclear ribonucleoprotein A1
Authors:Sun, Y.P, Zhao, K, Liu, C, Li, D.
Deposit date:2020-04-17
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure.
Nat Commun, 11, 2020
1UP1
DownloadVisualize
BU of 1up1 by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
Authors:Xu, R.-M, Jokhan, L, Cheng, X, Mayeda, A, Krainer, A.R.
Deposit date:1997-03-12
Release date:1997-09-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs.
Structure, 5, 1997
5MPG
DownloadVisualize
BU of 5mpg by Molmil
Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, RNA UUAGGUC
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2016-12-16
Release date:2017-07-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife, 6, 2017
2LYV
DownloadVisualize
BU of 2lyv by Molmil
Solution structure of the two RRM domains of hnRNP A1 (UP1) using segmental isotope labeling
Descriptor: Heterogeneous nuclear ribonucleoprotein A1
Authors:Barraud, P, Allain, F.H.-T.
Deposit date:2012-09-19
Release date:2012-12-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology.
J.Biomol.Nmr, 55, 2013
2H4M
DownloadVisualize
BU of 2h4m by Molmil
Karyopherin Beta2/Transportin-M9NLS
Descriptor: Heterogeneous nuclear ribonucleoprotein A1, Transportin-1
Authors:Chook, Y.M, Cansizoglu, A.E.
Deposit date:2006-05-24
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rules for nuclear localization sequence recognition by karyopherin beta 2.
Cell(Cambridge,Mass.), 126, 2006
1U1K
DownloadVisualize
BU of 1u1k by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTT 7DA GGG); A Human Telomeric Repeat Containing 7-deaza-adenine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*(7DA)P*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1N
DownloadVisualize
BU of 1u1n by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTA (PRN)GG); A Human Telomeric Repeat Containing Nebularine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(PRN)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
5ZGD
DownloadVisualize
BU of 5zgd by Molmil
hnRNPA1 reversible amyloid core GFGGNDNFG (residues 209-217) determined by X-ray
Descriptor: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
Authors:Gui, X, Xie, M, Zhao, M, Luo, F, He, J, Li, D, Liu, C.
Deposit date:2018-03-08
Release date:2019-04-03
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
5ZGL
DownloadVisualize
BU of 5zgl by Molmil
hnRNP A1 segment GGGYGGS (residues 234-240)
Descriptor: 7-mer peptide from Heterogeneous nuclear ribonucleoprotein A1
Authors:Xie, M, Luo, F, Gui, X, Zhao, M, He, J, Li, D, Liu, C.
Deposit date:2018-03-09
Release date:2019-04-03
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly.
Nat Commun, 10, 2019
6BXX
DownloadVisualize
BU of 6bxx by Molmil
GYNGFG from low-complexity domain of hnRNPA1, residues 243-248
Descriptor: hnRNPA1
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S.
Deposit date:2017-12-19
Release date:2018-04-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
6DCL
DownloadVisualize
BU of 6dcl by Molmil
Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
Descriptor: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
Authors:Kooshapur, H, Sattler, M.
Deposit date:2018-05-07
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
8IK7
DownloadVisualize
BU of 8ik7 by Molmil
Cryo-EM structure of hnRAC1 fibril.
Descriptor: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-02-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Formed fibrils of hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217)
To Be Published
8IKS
DownloadVisualize
BU of 8iks by Molmil
Cryo-EM structure of hnRAC1-2I8I fibril.
Descriptor: GLY-PHI-GLY-GLY-ASN-ASP-ASN-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-03-01
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Cryo-EM structure of hnRAC1-2I8I fibril.
To Be Published
8IKP
DownloadVisualize
BU of 8ikp by Molmil
Cryo-EM structure of hnRAC1-8I fibril
Descriptor: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-02-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Cryo-EM structure of hnRAC1-8I fibril
To Be Published
8IKB
DownloadVisualize
BU of 8ikb by Molmil
Cryo-EM structure of hnRAC1-2I fibril.
Descriptor: GLY-PHI-GLY-GLY-ASN-ASP-ASN-PHE-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-02-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Cryo-EM structure of hnRAC1-2I fibril.
To Be Published
1PO6
DownloadVisualize
BU of 1po6 by Molmil
Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
Descriptor: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Moore, S.A, Shamoo, Y.
Deposit date:2003-06-13
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.BIOL.CHEM., 278, 2003

 

123>

225681

PDB entries from 2024-10-02

PDB statisticsPDBj update infoContact PDBjnumon