7BX7

Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain

Summary for 7BX7

• Entry DOI: 10.2210/pdb7bx7/pdb
• EMDB information: 30235
• Descriptor: Heterogeneous nuclear ribonucleoprotein A1 (1 entity in total)
• Functional Keywords: amyloid fibril, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 78494.53

Authors

Sun, Y.P.,Zhao, K.,Liu, C.,Li, D. (deposition date: 2020-04-17, release date: 2020-11-18, Last modification date: 2024-03-27)

• Primary citation: Sun, Y.,Zhao, K.,Xia, W.,Feng, G.,Gu, J.,Ma, Y.,Gui, X.,Zhang, X.,Fang, Y.,Sun, B.,Wang, R.,Liu, C.,Li, D.; The nuclear localization sequence mediates hnRNPA1 amyloid fibril formation revealed by cryoEM structure.; Nat Commun, 11:6349-6349, 2020; PubMed: 33311513; DOI: 10.1038/s41467-020-20227-8

Experimental method

ELECTRON MICROSCOPY (2.8 Å)