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PDB: 13 results

4U1M
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BU of 4u1m by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1N
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BU of 4u1n by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U5W
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BU of 4u5w by Molmil
Crystal Structure of HIV-1 Nef-SF2 Core Domain in Complex with the Src Family Kinase Hck SH3-SH2 Tandem Regulatory Domains
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, Protein Nef, ...
Authors:Alvarado, J.J, Yeh, J.I, Smithgall, T.E.
Deposit date:2014-07-25
Release date:2014-08-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Interaction with the Src Homology (SH3-SH2) Region of the Src-family Kinase Hck Structures the HIV-1 Nef Dimer for Kinase Activation and Effector Recruitment.
J.Biol.Chem., 289, 2014
4ORZ
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HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain
Descriptor: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19
Authors:Geyer, M, Lulf, S.
Deposit date:2014-02-12
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody.
Retrovirology, 11, 2014
3REA
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BU of 3rea by Molmil
HIV-1 Nef protein in complex with engineered Hck-SH3 domain
Descriptor: Protein Nef, Tyrosine-protein kinase HCK
Authors:Schulte, A, Blankenfeldt, W, Geyer, M.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
PLoS ONE, 6, 2011
4U1L
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BU of 4u1l by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1K
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BU of 4u1k by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
3RBB
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BU of 3rbb by Molmil
HIV-1 NEF protein in complex with engineered HCK SH3 domain
Descriptor: 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK
Authors:Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M.
Deposit date:2011-03-29
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly.
Traffic, 12, 2011
8F2P
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BU of 8f2p by Molmil
Nef SF2 dimerization mutant bound to Hck SH3
Descriptor: C-terminal core protein, Tyrosine-protein kinase HCK
Authors:Thomas, C.E, Alvarado, J.J, Smithgall, T.E.
Deposit date:2022-11-08
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers.
J.Mol.Biol., 435, 2023
5XOV
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BU of 5xov by Molmil
Crystal structure of peptide-HLA-A24 bound to S19-2 V-delta/V-beta TCR
Descriptor: Beta-2-microglobulin, HIV-1 Nef138-10 peptide, HLA class I histocompatibility antigen, ...
Authors:Shi, Y, Qi, J, Gao, G.F.
Deposit date:2017-05-31
Release date:2017-06-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.684 Å)
Cite:Conserved V delta 1 Binding Geometry in a Setting of Locus-Disparate pHLA Recognition by delta / alpha beta T Cell Receptors (TCRs): Insight into Recognition of HIV Peptides by TCRs.
J. Virol., 91, 2017
6B72
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BU of 6b72 by Molmil
A novel HIV-1 Nef dimer interface induced by a single octyl-glucoside molecule
Descriptor: Protein Nef, octyl beta-D-glucopyranoside
Authors:Wu, M, Augelli-Szafran, C.E, Ptak, R.G, Smithgall, T.E.
Deposit date:2017-10-03
Release date:2018-02-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A single beta-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding.
PLoS ONE, 13, 2018
7D7S
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BU of 7d7s by Molmil
HIV-1 SF2 Nef in complex with the Fyn SH3 R96I mutant
Descriptor: Protein Nef, Tyrosine-protein kinase Fyn
Authors:Aldehaiman, A, Shahul Hamed, U.F, Arold, S.T.
Deposit date:2020-10-05
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3REB
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BU of 3reb by Molmil
HIV-1 Nef protein in complex with engineered Hck-SH3 domain
Descriptor: Protein Nef, Tyrosine-protein kinase HCK
Authors:Schulte, A, Blankenfeldt, W, Geyer, M.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
PLoS ONE, 6, 2011

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