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PDB: 15 results
3CBZ
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BU of 3cbz by Molmil
The Dvl2 PDZ Domain in Complex with the N2 Inhibitory Peptide
Descriptor: 1,2-ETHANEDIOL, Dishevelled-2, PHOSPHATE ION
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2008-02-23
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
3CBY
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BU of 3cby by Molmil
The Dvl2 PDZ Domain in Complex with the N1 Inhibitory Peptide
Descriptor: 1,2-ETHANEDIOL, Dishevelled-2
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2008-02-23
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
2REY
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BU of 2rey by Molmil
Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh)
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Papagrigoriou, E, Gileadi, C, Elkins, J, Cooper, C, Ugochukwu, E, Turnbull, A, Pike, A.C.W, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2007-09-27
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
6IW3
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BU of 6iw3 by Molmil
High resolution structure of Dvl2-DIX Y27W/C80S mutant
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Yamanishi, K, Shibata, N.
Deposit date:2018-12-04
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:High-resolution structure of a Y27W mutant of the Dishevelled2 DIX domain.
Acta Crystallogr F Struct Biol Commun, 75, 2019
3CBX
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BU of 3cbx by Molmil
The Dvl2 PDZ Domain in Complex with the C1 Inhibitory Peptide
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Dishevelled-2
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2008-02-23
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
3CC0
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BU of 3cc0 by Molmil
The Dvl2 PDZ Domain in Complex with the N3 Inhibitory Peptide
Descriptor: Dishevelled-2
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2008-02-23
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
8WWR
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BU of 8wwr by Molmil
Crystal structure of apo human dishevelled 2 (Dvl2) PDZ domain
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Omble, A, Mahajan, S, Kulkarni, K.A.
Deposit date:2023-10-26
Release date:2024-05-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
5SUZ
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BU of 5suz by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: C-centered monoclinic crystal form crystallised from monomeric fraction
Descriptor: Segment polarity protein dishevelled homolog DVL-2
Authors:Renko, M, Gammons, M.V, Bienz, M.
Deposit date:2016-08-04
Release date:2016-10-12
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
5SUY
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BU of 5suy by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from dimeric fraction
Descriptor: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
Authors:Renko, M, Gammons, M.V, Bienz, M.
Deposit date:2016-08-04
Release date:2016-10-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
5LNP
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BU of 5lnp by Molmil
Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction
Descriptor: SULFATE ION, Segment polarity protein dishevelled homolog DVL-2
Authors:Renko, M, Gammons, M.V, Bienz, M.
Deposit date:2016-08-05
Release date:2016-10-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled.
Mol.Cell, 64, 2016
4WIP
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BU of 4wip by Molmil
DIX domain of human Dvl2
Descriptor: PENTAETHYLENE GLYCOL, Segment polarity protein dishevelled homolog DVL-2
Authors:Fiedler, M, Bienz, M, Madrzak, J, Chin, J.W.
Deposit date:2014-09-26
Release date:2015-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
Nat Commun, 6, 2015
8YR7
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BU of 8yr7 by Molmil
Crystal structure of human dishevelled 2 (Dvl2) PDZ domain fused with WGEF internal peptide motif
Descriptor: Segment polarity protein dishevelled homolog DVL-2,Rho guanine nucleotide exchange factor 19
Authors:Omble, A, Mahajan, S, Kulkarni, K.A.
Deposit date:2024-03-20
Release date:2024-05-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF.
Commun Biol, 7, 2024
6JCK
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BU of 6jck by Molmil
Complex structure of Axin-DIX and Dvl2-DIX
Descriptor: Axin-1, Segment polarity protein dishevelled homolog DVL-2
Authors:Yamanishi, K, Shibata, N.
Deposit date:2019-01-29
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to beta-catenin.
Sci.Signal., 12, 2019
8WMA
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BU of 8wma by Molmil
Fzd4/DEP complex (local refined)
Descriptor: Frizzled-4, Segment polarity protein dishevelled homolog DVL-2
Authors:He, Y, Qian, Y.
Deposit date:2023-10-03
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural basis of Frizzled 4 in recognition of Dishevelled 2 unveils mechanism of WNT signaling activation.
Nat Commun, 15, 2024
8WM9
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BU of 8wm9 by Molmil
Fzd4/DEP complex
Descriptor: CHOLESTEROL HEMISUCCINATE, Frizzled-4, Segment polarity protein dishevelled homolog DVL-2
Authors:He, Y, Qian, Y.
Deposit date:2023-10-03
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural basis of Frizzled 4 in recognition of Dishevelled 2 unveils mechanism of WNT signaling activation.
Nat Commun, 15, 2024

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PDB entries from 2024-10-09

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