8WWR

Crystal structure of apo human dishevelled 2 (Dvl2) PDZ domain

Summary for 8WWR

Entry DOI	10.2210/pdb8wwr/pdb
Descriptor	Segment polarity protein dishevelled homolog DVL-2 (2 entities in total)
Functional Keywords	wnt signaling, signaling protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	10219.76
Authors	Omble, A.,Mahajan, S.,Kulkarni, K.A. (deposition date: 2023-10-26, release date: 2024-05-29)
Primary citation	Omble, A.,Mahajan, S.,Bhoite, A.,Kulkarni, K. Dishevelled2 activates WGEF via its interaction with a unique internal peptide motif of the GEF. Commun Biol, 7:543-543, 2024 Cited by PubMed: 38714795 DOI: 10.1038/s42003-024-06194-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation