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PDB: 8 results

3SFY
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BU of 3sfy by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and ethylenediamine inhibitor 2
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Cryptococcus neoformans protein farnesyltransferase alpha subunit, Cryptococcus neoformans protein farnesyltransferase beta subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-06-14
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3Q7F
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BU of 3q7f by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, FARNESYL DIPHOSPHATE, Farnesyltransferase alpha subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-01-04
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3SFX
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BU of 3sfx by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, Cryptococcus neoformans protein farnesyltransferase alpha subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-06-14
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3Q79
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BU of 3q79 by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with farnesyl-DDPTASACNIQ product
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, FARNESYL, Farnesyltransferase alpha subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-01-04
Release date:2011-08-03
Last modified:2011-10-19
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3Q7A
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BU of 3q7a by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and L-778,123
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE, FARNESYL DIPHOSPHATE, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-01-04
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3Q78
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BU of 3q78 by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FSPP and DDPTASACNIQ peptide
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Farnesyltransferase alpha subunit, Farnesyltransferase beta subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-01-04
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3Q73
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BU of 3q73 by Molmil
Cryptococcus neoformans protein farnesyltransferase, apo enzyme
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Farnesyltransferase, alpha subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-01-04
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3Q75
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BU of 3q75 by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and TKCVVM peptide
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Farnesyltransferase alpha subunit, Farnesyltransferase beta subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-01-04
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011

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