3Q75
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and TKCVVM peptide
Summary for 3Q75
| Entry DOI | 10.2210/pdb3q75/pdb |
| Related | 3Q73 3Q78 3Q79 3Q7A 3Q7F 3SFX 3SFY |
| Descriptor | Farnesyltransferase alpha subunit, Farnesyltransferase beta subunit, Hexapeptide TKCVVM, ... (7 entities in total) |
| Functional Keywords | protein prenyltransferase, transferase |
| Biological source | Cryptococcus neoformans More |
| Total number of polymer chains | 3 |
| Total formula weight | 99300.45 |
| Authors | Hast, M.A.,Beese, L.S. (deposition date: 2011-01-04, release date: 2011-08-03, Last modification date: 2024-02-21) |
| Primary citation | Hast, M.A.,Nichols, C.B.,Armstrong, S.M.,Kelly, S.M.,Hellinga, H.W.,Alspaugh, J.A.,Beese, L.S. Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens. J.Biol.Chem., 286:35149-35162, 2011 Cited by PubMed: 21816822DOI: 10.1074/jbc.M111.250506 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
Download full validation report
