3Q78
Cryptococcus neoformans protein farnesyltransferase in complex with FSPP and DDPTASACNIQ peptide
Summary for 3Q78
Entry DOI | 10.2210/pdb3q78/pdb |
Related | 3Q73 3Q75 3Q79 3Q7A 3Q7F 3SFX 3SFY |
Descriptor | Farnesyltransferase alpha subunit, Farnesyltransferase beta subunit, peptide substrate, ... (7 entities in total) |
Functional Keywords | protein prenyltransferase, transferase |
Biological source | Cryptococcus neoformans More |
Total number of polymer chains | 3 |
Total formula weight | 99792.72 |
Authors | Hast, M.A.,Beese, L.S. (deposition date: 2011-01-04, release date: 2011-08-03, Last modification date: 2024-02-21) |
Primary citation | Hast, M.A.,Nichols, C.B.,Armstrong, S.M.,Kelly, S.M.,Hellinga, H.W.,Alspaugh, J.A.,Beese, L.S. Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens. J.Biol.Chem., 286:35149-35162, 2011 Cited by PubMed: 21816822DOI: 10.1074/jbc.M111.250506 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)