3Q79
Cryptococcus neoformans protein farnesyltransferase in complex with farnesyl-DDPTASACNIQ product
Summary for 3Q79
| Entry DOI | 10.2210/pdb3q79/pdb |
| Related | 3Q73 3Q75 3Q78 3Q7A 3Q7F 3SFX 3SFY |
| Descriptor | Farnesyltransferase alpha subunit, Farnesyltransferase beta subunit, isoprenylated product, ... (8 entities in total) |
| Functional Keywords | protein prenyltransferase, transferase |
| Biological source | Cryptococcus neoformans More |
| Total number of polymer chains | 3 |
| Total formula weight | 99934.07 |
| Authors | Hast, M.A.,Beese, L.S. (deposition date: 2011-01-04, release date: 2011-08-03, Last modification date: 2011-10-19) |
| Primary citation | Hast, M.A.,Nichols, C.B.,Armstrong, S.M.,Kelly, S.M.,Hellinga, H.W.,Alspaugh, J.A.,Beese, L.S. Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens. J.Biol.Chem., 286:35149-35162, 2011 Cited by PubMed: 21816822DOI: 10.1074/jbc.M111.250506 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.506 Å) |
Structure validation
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