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1DKI
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BU of 1dki by Molmil
CRYSTAL STRUCTURE OF THE ZYMOGEN FORM OF STREPTOCOCCAL PYROGENIC EXOTOXIN B ACTIVE SITE (C47S) MUTANT
Descriptor: PYROGENIC EXOTOXIN B ZYMOGEN, SULFATE ION
Authors:Kagawa, T.F, Cooney, J.C, Baker, H.M, McSweeney, S, Liu, M, Gubba, S, Musser, J.M, Baker, E.N.
Deposit date:1999-12-07
Release date:2000-03-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease.
Proc.Natl.Acad.Sci.USA, 97, 2000
3BHX
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BU of 3bhx by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a transition state analog of Asp-Glu
Descriptor: (2S)-2-{[(S)-(2-carboxyethyl)(hydroxy)phosphoryl]methyl}pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lubkowski, J, Barinka, C.
Deposit date:2007-11-29
Release date:2008-01-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs
J.Mol.Biol., 376, 2008
4N0D
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BU of 4n0d by Molmil
Crystal structure of the K345L variant of the Gi alpha1 subunit bound to GTPgammaS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, MAGNESIUM ION, ...
Authors:Thaker, T.M, Preininger, A.M, Sarwar, M, Hamm, H.E, Iverson, T.M.
Deposit date:2013-10-01
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A Transient Interaction between the Phosphate Binding Loop and Switch I Contributes to the Allosteric Network between Receptor and Nucleotide in G alpha i1.
J.Biol.Chem., 289, 2014
7CJZ
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BU of 7cjz by Molmil
Room temperature structure of lysozyme delivered in lard by serial millisecond crystallography
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Nam, K.H.
Deposit date:2020-07-15
Release date:2020-11-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Lard Injection Matrix for Serial Crystallography.
Int J Mol Sci, 21, 2020
2H1N
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BU of 2h1n by Molmil
3.0 A X-ray structure of putative oligoendopeptidase F: crystals grown by vapor diffusion technique
Descriptor: Oligoendopeptidase F, UNKNOWN LIGAND, ZINC ION
Authors:Gerdts, C.J, Tereshko, V, Dementieva, I, Collart, F, Joachimiak, A, Kossiakoff, A, Ismagilov, R.F, Midwest Center for Structural Genomics (MCSG)
Deposit date:2006-05-16
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization.
Angew.Chem.Int.Ed.Engl., 45, 2006
1DYL
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BU of 1dyl by Molmil
9 ANGSTROM RESOLUTION CRYO-EM RECONSTRUCTION STRUCTURE OF SEMLIKI FOREST VIRUS (SFV) AND FITTING OF THE CAPSID PROTEIN STRUCTURE IN THE EM DENSITY
Descriptor: NUCLEOCAPSID PROTEIN
Authors:Mancini, E.J, Clarke, M, Gowen, B.E, Rutten, T, Fuller, S.D.
Deposit date:2000-02-02
Release date:2000-08-18
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Electron Microscopy Reveals the Functional Organization of an Enveloped Virus, Semliki Forest Virus.
Mol.Cell, 5, 2000
1DJB
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BU of 1djb by Molmil
STRUCTURE OF BETA-LACTAMASE PRECURSOR, S70A MUTANT, AT 298K
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1996-08-13
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1.
Biochemistry, 35, 1996
1DRE
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BU of 1dre by Molmil
DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM)
Descriptor: DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sawaya, M.R, Kraut, J.
Deposit date:1996-11-28
Release date:1997-03-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence.
Biochemistry, 36, 1997
4N14
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BU of 4n14 by Molmil
Crystal structure of Cdc20 and apcin complex
Descriptor: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl [(1R)-2,2,2-trichloro-1-(pyrimidin-2-ylamino)ethyl]carbamate, Cell division cycle protein 20 homolog
Authors:Luo, X, Tian, W, Yu, H.
Deposit date:2013-10-03
Release date:2014-08-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.
Nature, 514, 2014
2KLK
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BU of 2klk by Molmil
Solution structure of GB1 A34F mutant with RDC and SAXS
Descriptor: IMMUNOGLOBULIN G-BINDING PROTEIN G
Authors:Wang, J, Zuo, X, Yu, P, Byeon, I.L, Jung, J, Schwieters, C.D, Gronenborn, A.M, Wang, Y.
Deposit date:2009-07-06
Release date:2009-10-06
Last modified:2024-05-22
Method:SOLUTION NMR, SOLUTION SCATTERING
Cite:Determination of multicomponent protein structures in solution using global orientation and shape restraints.
J.Am.Chem.Soc., 131, 2009
2KEH
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BU of 2keh by Molmil
Plantaricin K in TFE
Descriptor: PlnK
Authors:Rogne, P, Haugen, M, Nissen-Meyer, J, Kristiansen, P.
Deposit date:2009-01-30
Release date:2009-07-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional structure of the two-peptide bacteriocin plantaricin JK.
Peptides, 30, 2009
4Q2K
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BU of 4q2k by Molmil
Bovine alpha chymotrypsin bound to a cyclic peptide inhibitor, 5b
Descriptor: (11S)-4,9-dioxo-N-[(2S)-1-oxo-3-phenylpropan-2-yl]-17,22-dioxa-10,30-diazatetracyclo[21.2.2.2~13,16~.1~5,8~]triaconta-1(25),5,7,13,15,23,26,28-octaene-11-carboxamide, Chymotrypsinogen A
Authors:Chan, H.Y, Bruning, J.B, Abell, A.D.
Deposit date:2014-04-09
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Macrocyclic protease inhibitors with reduced peptide character.
Angew.Chem.Int.Ed.Engl., 53, 2014
2KPE
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BU of 2kpe by Molmil
Refined structure of Glycophorin A transmembrane segment dimer in DPC micelles
Descriptor: Glycophorin-A
Authors:Mineev, K.S, Bocharov, E.V, Goncharuk, M.V, Arseniev, A.S, Volynsky, P.E, Efremov, R.G.
Deposit date:2009-10-13
Release date:2010-09-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Dimeric structure of the transmembrane domain of glycophorin a in lipidic and detergent environments.
Acta Naturae, 3, 2011
2KHF
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BU of 2khf by Molmil
Plantaricin J in DPC-micelles
Descriptor: PlnJ
Authors:Rogne, P, Haugen, C, Kristiansen, P.E, Nissen-Meyer, J.
Deposit date:2009-04-03
Release date:2009-06-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Three-Dimensional Structure of the Two-Peptide Bacteriocin Plantaricin JK.
Peptides, 2009
1H7Y
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BU of 1h7y by Molmil
Translationally Controlled Tumor-associated Protein p23fyp from Schizosaccharomyces pombe
Descriptor: TRANSLATIONALLY CONTROLLED TUMOR PROTEIN
Authors:Thaw, P, Baxter, N.J, Sedelnikova, S.E, Price, C, Waltho, J.P, Craven, C.J.
Deposit date:2001-01-19
Release date:2001-08-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones.
Nat. Struct. Biol., 8, 2001
2CWW
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BU of 2cww by Molmil
Crystal structure of Thermus thermophilus TTHA1280, a putative SAM-dependent RNA methyltransferase, in complex with S-adenosyl-L-homocysteine
Descriptor: ACETIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-06-27
Release date:2005-10-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
7CQF
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BU of 7cqf by Molmil
Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CHOLINE ION, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2020-08-10
Release date:2021-01-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention.
Proc.Natl.Acad.Sci.USA, 118, 2021
2KS0
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BU of 2ks0 by Molmil
Solution NMR structure of the Q251Q8_DESHY(21-82) protein from Desulfitobacterium Hafniense, Northeast Structural Genomics Consortium Target DhR8C
Descriptor: Uncharacterized protein
Authors:Yang, Y, Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Foote, E.L, Jiang, M, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-12-23
Release date:2010-01-12
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Combining NMR and EPR methods for homodimer protein structure determination.
J.Am.Chem.Soc., 132, 2010
3AY9
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BU of 3ay9 by Molmil
Crystal structure of human Hsp70 NBD in the ADP-, Mg ion-, and K ion-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ...
Authors:Arakawa, A, Handa, N, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2011-05-03
Release date:2011-12-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Biochemical and structural studies on the high affinity of Hsp70 for ADP.
Protein Sci., 20, 2011
1E8L
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BU of 1e8l by Molmil
NMR solution structure of hen lysozyme
Descriptor: LYSOZYME
Authors:Schwalbe, H, Grimshaw, S.B, Spencer, A, Buck, M, Boyd, J, Dobson, C.M, Redfield, C, Smith, L.J.
Deposit date:2000-09-27
Release date:2000-10-09
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:A refined solution structure of hen lysozyme determined using residual dipolar coupling data.
Protein Sci., 10, 2001
2H9X
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BU of 2h9x by Molmil
NMR structure for the CgNa toxin from the sea anemone Condylactis gigantea
Descriptor: Toxin CgNa
Authors:Lopez-Mendez, B, Perez-Castells, J, Gimenez-Gallego, G, Jimenez-Barbero, J.
Deposit date:2006-06-12
Release date:2007-06-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:CgNa, a type I toxin from the giant Caribbean sea anemone Condylactis gigantea shows structural similarities to both type I and II toxins, as well as distinctive structural and functional properties(1).
Biochem.J., 406, 2007
2DPE
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BU of 2dpe by Molmil
Crystal structure of a secretory 40KDA glycoprotein from sheep at 2.0A resolution
Descriptor: Chitinase-3-like protein 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Srivastava, D.B, Ethayathulla, A.S, Kumar, J, Singh, N, Sharma, S, Das, U, Srinivasan, A, Singh, T.P.
Deposit date:2006-05-11
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of a secretory signalling glycoprotein from sheep at 2.0A resolution
J.Struct.Biol., 156, 2006
2H53
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BU of 2h53 by Molmil
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Descriptor: small heat shock protein Hsp26
Authors:White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
2YH6
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BU of 2yh6 by Molmil
Structure of the N-terminal domain of BamC from E. coli
Descriptor: LIPOPROTEIN 34, SULFATE ION
Authors:Zeth, K, Albrecht, R.
Deposit date:2011-04-27
Release date:2011-05-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Basis of Outer Membrane Protein Biogenesis in Bacteria.
J.Biol.Chem., 286, 2011
4LWU
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BU of 4lwu by Molmil
The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252
Descriptor: (2'S,3R,4'S,5'R)-N-(4-carbamoylphenyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide, E3 ubiquitin-protein ligase Mdm2, SULFATE ION
Authors:Graves, B.J, Lukacs, C, Janson, C.A.
Deposit date:2013-07-28
Release date:2014-07-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy.
Bioorg.Med.Chem., 22, 2014

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數據於2024-10-09公開中

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