1DKI

CRYSTAL STRUCTURE OF THE ZYMOGEN FORM OF STREPTOCOCCAL PYROGENIC EXOTOXIN B ACTIVE SITE (C47S) MUTANT

Summary for 1DKI

Entry DOI	10.2210/pdb1dki/pdb
Descriptor	PYROGENIC EXOTOXIN B ZYMOGEN, SULFATE ION (3 entities in total)
Functional Keywords	zymogen, cysteine protease, papain-like, toxin
Biological source	Streptococcus pyogenes
Cellular location	Secreted: P0C0J0
Total number of polymer chains	4
Total formula weight	161658.36
Authors	Kagawa, T.F.,Cooney, J.C.,Baker, H.M.,McSweeney, S.,Liu, M.,Gubba, S.,Musser, J.M.,Baker, E.N. (deposition date: 1999-12-07, release date: 2000-03-01, Last modification date: 2024-02-07)
Primary citation	Kagawa, T.F.,Cooney, J.C.,Baker, H.M.,McSweeney, S.,Liu, M.,Gubba, S.,Musser, J.M.,Baker, E.N. Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: an integrin-binding cysteine protease. Proc.Natl.Acad.Sci.USA, 97:2235-2240, 2000 Cited by PubMed: 10681429 DOI: 10.1073/pnas.040549997 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation