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4BZ6
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BU of 4bz6 by Molmil
Crystal structure of Schistosoma mansoni HDAC8 complexed with SAHA
Descriptor: DIMETHYLFORMAMIDE, GLYCEROL, HISTONE DEACETYLASE 8, ...
Authors:Marek, M, Romier, C.
Deposit date:2013-07-24
Release date:2013-08-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni.
Plos Pathog., 9, 2013
4BZ7
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BU of 4bz7 by Molmil
Crystal structure of Schistosoma mansoni HDAC8 complexed with M344
Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, HISTONE DEACETYLASE 8, ...
Authors:Marek, M, Romier, C.
Deposit date:2013-07-24
Release date:2013-08-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni.
Plos Pathog., 9, 2013
4BZ9
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BU of 4bz9 by Molmil
Crystal structure of Schistosoma mansoni HDAC8 complexed with J1075
Descriptor: 3-chlorobenzothiophene-2-carbohydroxamic acid, DIMETHYLFORMAMIDE, GLYCEROL, ...
Authors:Marek, M, Romier, C.
Deposit date:2013-07-24
Release date:2013-08-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni.
Plos Pathog., 9, 2013
4BZ5
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BU of 4bz5 by Molmil
Crystal structure of Schistosoma mansoni HDAC8
Descriptor: HISTONE DEACETYLASE 8, L(+)-TARTARIC ACID, POTASSIUM ION, ...
Authors:Marek, M, Romier, C.
Deposit date:2013-07-24
Release date:2013-08-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.785 Å)
Cite:Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni.
Plos Pathog., 9, 2013
4BVX
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BU of 4bvx by Molmil
Crystal structure of the AIMP3-MRS N-terminal domain complex with I3C
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, METHIONINE--TRNA LIGASE, ...
Authors:Cho, H.Y, Seo, W.W, Cho, H.J, Kang, B.S.
Deposit date:2013-06-29
Release date:2014-07-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Assembly of Multi-tRNA Synthetase Complex Via Heterotetrameric Glutathione Transferase-Homology Domains.
J.Biol.Chem., 290, 2015
4BXU
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BU of 4bxu by Molmil
Structure of Pex14 in complex with Pex5 LVxEF motif
Descriptor: PEROXISOMAL MEMBRANE PROTEIN PEX14, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR
Authors:Kooshapur, H, Meyer, H.N, Madl, T, Sattler, M.
Deposit date:2013-07-15
Release date:2013-11-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A Novel Pex14 Interacting Site of Human Pex5 is Critical for Matrix Protein Import Into Peroxisomes.
J.Biol.Chem., 289, 2014
8G20
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BU of 8g20 by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with inhibitor Mz327
Descriptor: 1,2-ETHANEDIOL, 4-[(N-butylpentanamido)methyl]-N-hydroxybenzamide, ETHANOL, ...
Authors:Tararina, M.A, Christianson, D.W.
Deposit date:2023-02-03
Release date:2023-12-13
Method:X-RAY DIFFRACTION (1.766 Å)
Cite:Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
J.Med.Chem., 66, 2023
8G1Z
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BU of 8g1z by Molmil
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with inhibitor Mz317
Descriptor: 1,2-ETHANEDIOL, 4-(acetamidomethyl)-N-hydroxybenzamide, Hdac6 protein, ...
Authors:Tararina, M.A, Christianson, D.W.
Deposit date:2023-02-03
Release date:2023-12-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
J.Med.Chem., 66, 2023
4PJO
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BU of 4pjo by Molmil
Minimal U1 snRNP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ETHANOL, ...
Authors:Kondo, Y, Oubridge, C, van Roon, A.M, Nagai, K.
Deposit date:2014-05-12
Release date:2014-12-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Elife, 4, 2015
4CQF
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BU of 4cqf by Molmil
Crystal structure of Schistosoma mansoni HDAC8 complexed with a mercaptoacetamide inhibitor
Descriptor: 6-(2-Mercaptoacetylamino)-N-phenylhexanamide, DIMETHYLFORMAMIDE, GLYCEROL, ...
Authors:Marek, M, Romier, C.
Deposit date:2014-02-14
Release date:2014-04-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Basis for the Anti-Parasitic Activity of a Mercaptoacetamide Derivative that Inhibits Histone Deacetylase 8 (Hdac8) from the Human Pathogen Schistosoma Mansoni
J.Mol.Biol., 426, 2014
2ZIU
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BU of 2ziu by Molmil
Crystal structure of the Mus81-Eme1 complex
Descriptor: Crossover junction endonuclease EME1, Mus81 protein
Authors:Chang, J.H, Kim, J.J, Choi, J.M, Lee, J.H, Cho, Y.
Deposit date:2008-02-25
Release date:2008-04-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Mus81-Eme1 complex
Genes Dev., 22, 2008
4BAE
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BU of 4bae by Molmil
Optimisation of pyrroleamides as mycobacterial GyrB ATPase inhibitors: Structure Activity Relationship and in vivo efficacy in the mouse model of tuberculosis
Descriptor: 2-[(3S,4R)-4-[(3-bromanyl-4-chloranyl-5-methyl-1H-pyrrol-2-yl)carbonylamino]-3-methoxy-piperidin-1-yl]-4-(2-methyl-1,2,4-triazol-3-yl)-1,3-thiazole-5-carboxylic acid, CALCIUM ION, DNA GYRASE SUBUNIT B, ...
Authors:Read, J.A, Gingell, H.G, Madhavapeddi, P.
Deposit date:2012-09-13
Release date:2013-10-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Optimization of Pyrrolamides as Mycobacterial Gyrb ATPase Inhibitors: Structure Activity Relationship and in Vivo Efficacy in the Mouse Model of Tuberculosis.
Antimicrob.Agents Chemother., 58, 2014
4D2K
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BU of 4d2k by Molmil
Crystal structure of DREP2 CIDE domain
Descriptor: DREP2
Authors:Jang, T.H, Park, H.H, Kim, Y.G, Jeong, J.H.
Deposit date:2014-05-12
Release date:2015-05-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:CIDE domains form functionally important higher-order assemblies for DNA fragmentation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2ZIV
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BU of 2ziv by Molmil
Crystal structure of the Mus81-Eme1 complex
Descriptor: Crossover junction endonuclease EME1, Mus81 protein
Authors:Chang, J.H, Kim, J.J, Choi, J.M, Lee, J.H, Cho, Y.
Deposit date:2008-02-25
Release date:2008-04-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Mus81-Eme1 complex
Genes Dev., 22, 2008
4CYD
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BU of 4cyd by Molmil
GlxR bound to cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, PROBABLE EXPRESSION TAG, ...
Authors:Townsend, P.D, Bott, M, Cann, M.J, Pohl, E.
Deposit date:2014-04-10
Release date:2014-12-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
4DDU
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BU of 4ddu by Molmil
Thermotoga maritima reverse gyrase, C2 FORM 1
Descriptor: Reverse gyrase, ZINC ION
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2012-01-19
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
4DDX
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BU of 4ddx by Molmil
Thermotoga maritima reverse gyrase, primitive monoclinic form
Descriptor: Reverse gyrase, ZINC ION
Authors:Rudolph, M.G, Klostermeier, D.
Deposit date:2012-01-19
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.17 Å)
Cite:Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.
Nucleic Acids Res., 41, 2013
4R1B
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BU of 4r1b by Molmil
Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
Descriptor: Apical membrane antigen 1, AMA1
Authors:Lim, S.S, Norton, R.S, McGowan, S.
Deposit date:2014-08-04
Release date:2015-01-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
7XD6
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BU of 7xd6 by Molmil
The Tet-S2 state with a pseudoknotted 4-way junction of wild-type Tetrahymena group I intron with 30nt 3'/5'-exon
Descriptor: MAGNESIUM ION, SPERMIDINE, The Tet-S2 state with a pseudoknotted 4-way junction molecule of co-transcriptional folded wild-type Tetrahymena group I intron with 30nt 3'/5'-exon (5'-exon), ...
Authors:Luo, B, Zhang, C, Ling, X, Mukherjee, S, Jia, G, Xie, J, Jia, X, Liu, L, Baulin, E.F, Luo, Y, Jiang, L, Dong, H, Wei, X, Bujnicki, J.M, Su, Z.
Deposit date:2022-03-26
Release date:2023-04-05
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing
Nat Catal, 2023
1LXT
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BU of 1lxt by Molmil
STRUCTURE OF PHOSPHOTRANSFERASE PHOSPHOGLUCOMUTASE FROM RABBIT
Descriptor: CADMIUM ION, PHOSPHOGLUCOMUTASE (DEPHOSPHO FORM), SULFATE ION
Authors:Ray Junior, W.J, Baranidharan, S, Liu, Y.
Deposit date:1996-07-28
Release date:1997-02-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution.
Acta Crystallogr.,Sect.D, 53, 1997
3CYY
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BU of 3cyy by Molmil
The crystal structure of ZO-1 PDZ2 in complex with the Cx43 peptide
Descriptor: Tight junction protein ZO-1, peptide from Gap junction alpha-1 protein
Authors:Pan, L, Zhang, M.
Deposit date:2008-04-27
Release date:2008-09-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
Embo J., 27, 2008
2WV4
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BU of 2wv4 by Molmil
Crystal structure of foot-and-mouth disease virus 3C protease in complex with a decameric peptide corresponding to the VP1-2A cleavage junction
Descriptor: FOOT AND MOUTH DISEASE VIRUS (SEROTYPE A) VARIANT VP1 CAPSID PROTEIN, PICORNAIN 3C
Authors:Zunszain, P.A, Knox, S.R, Sweeney, T.R, Yang, J, Roque-Rosell, N, Belsham, G.J, Leatherbarrow, R.J, Curry, S.
Deposit date:2009-10-13
Release date:2009-10-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights Into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate.
J.Mol.Biol., 395, 2010
6YKR
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BU of 6ykr by Molmil
Structure of a protonation mimic of unplugged C. jejuni MotAB
Descriptor: Chemotaxis protein MotA, putative, Chemotaxis protein MotB
Authors:Santiveri, M, Roa-Eguiara, A, Taylor, N.M.I.
Deposit date:2020-04-06
Release date:2020-09-30
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and Function of Stator Units of the Bacterial Flagellar Motor.
Cell, 183, 2020
6YKP
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BU of 6ykp by Molmil
Structure of unplugged C. jejuni MotAB
Descriptor: Chemotaxis protein MotA, putative, Chemotaxis protein MotB
Authors:Santiveri, M, Roa-Eguiara, A, Taylor, N.M.I.
Deposit date:2020-04-06
Release date:2020-09-30
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structure and Function of Stator Units of the Bacterial Flagellar Motor.
Cell, 183, 2020
6YKM
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BU of 6ykm by Molmil
Structure of C. jejuni MotAB
Descriptor: Chemotaxis protein MotA, putative, Chemotaxis protein MotB
Authors:Santiveri, M, Roa-Eguiara, A, Taylor, N.M.I.
Deposit date:2020-04-06
Release date:2020-09-30
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and Function of Stator Units of the Bacterial Flagellar Motor.
Cell, 183, 2020

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數據於2024-06-26公開中

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