Crystal Structure of 3D7 strain Plasmodium falciparum AMA1

Summary for 4R1B

Related4R19 4R1A 4R1C
DescriptorApical membrane antigen 1, AMA1 (2 entities in total)
Functional Keywordspan fold, erythrocyte invasion by merozoites, ron2, moving junction complex, cell invasion
Biological sourcePlasmodium falciparum 3D7
Total number of polymer chains1
Total molecular weight38360.05
Lim, S.S.,Norton, R.S.,McGowan, S. (deposition date: 2014-08-04, release date: 2015-01-14)
Primary citation
Lim, S.S.,Yang, W.,Krishnarjuna, B.,Kannan Sivaraman, K.,Chandrashekaran, I.R.,Kass, I.,MacRaild, C.A.,Devine, S.M.,Debono, C.O.,Anders, R.F.,Scanlon, M.J.,Scammells, P.J.,Norton, R.S.,McGowan, S.
Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53:7310-7320, 2014
PubMed: 25360546 (PDB entries with the same primary citation)
DOI: 10.1021/bi5012089
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20950.4%07.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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