4BZ5
Crystal structure of Schistosoma mansoni HDAC8
Summary for 4BZ5
Entry DOI | 10.2210/pdb4bz5/pdb |
Related | 4BZ6 4BZ7 4BZ8 4BZ9 |
Descriptor | HISTONE DEACETYLASE 8, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase, platyhelminths, inhibition |
Biological source | SCHISTOSOMA MANSONI |
Total number of polymer chains | 4 |
Total formula weight | 202954.27 |
Authors | Marek, M.,Romier, C. (deposition date: 2013-07-24, release date: 2013-08-14, Last modification date: 2023-12-20) |
Primary citation | Marek, M.,Kannan, S.,Hauser, A.,Moraes Mourao, M.,Caby, S.,Cura, V.,Stolfa, D.A.,Schmidtkunz, K.,Lancelot, J.,Andrade, L.,Renaud, J.,Oliveira, G.,Sippl, W.,Jung, M.,Cavarelli, J.,Pierce, R.J.,Romier, C. Structural Basis for the Inhibition of Histone Deacetylase 8 (Hdac8), a Key Epigenetic Player in the Blood Fluke Schistosoma Mansoni. Plos Pathog., 9:03645-, 2013 Cited by PubMed: 24086136DOI: 10.1371/JOURNAL.PPAT.1003645 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.785 Å) |
Structure validation
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