2GLX
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![BU of 2glx by Molmil](/molmil-images/mine/2glx) | Crystal Structure Analysis of bacterial 1,5-AF Reductase | Descriptor: | 1,5-anhydro-D-fructose reductase, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Dambe, T.R, Scheidig, A.J. | Deposit date: | 2006-04-05 | Release date: | 2006-08-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of NADP(H)-Dependent 1,5-Anhydro-d-fructose Reductase from Sinorhizobium morelense at 2.2 A Resolution: Construction of a NADH-Accepting Mutant and Its Application in Rare Sugar Synthesis Biochemistry, 45, 2006
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1O5M
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![BU of 1o5m by Molmil](/molmil-images/mine/1o5m) | Structure of FPT bound to the inhibitor SCH66336 | Descriptor: | 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase alpha subunit, ... | Authors: | Strickland, C.L, Weber, P.C, Ganguly, A.K. | Deposit date: | 2003-09-26 | Release date: | 2003-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Tricyclic Farnesyl Protein Transferase Inhibitors: Crystallographic and Calorimetric Studies of Structure-Activity Relationships J.Med.Chem., 42, 1999
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1NQF
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![BU of 1nqf by Molmil](/molmil-images/mine/1nqf) | OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI, METHIONINE SUBSTIUTION CONSTRUCT FOR SE-MET SAD PHASING | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MAGNESIUM ION, Vitamin B12 receptor | Authors: | Chimento, D.P, Mohanty, A.K, Kadner, R.J, Wiener, M.C. | Deposit date: | 2003-01-21 | Release date: | 2003-04-29 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Substrate-induced transmembrane signaling in the cobalamin transporter BtuB Nat.Struct.Biol., 10, 2003
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2GST
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![BU of 2gst by Molmil](/molmil-images/mine/2gst) | STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE | Descriptor: | GLUTATHIONE S-TRANSFERASE, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, SULFATE ION | Authors: | Ji, X, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1993-06-07 | Release date: | 1993-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene. Biochemistry, 33, 1994
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1SYK
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![BU of 1syk by Molmil](/molmil-images/mine/1syk) | Crystal structure of E230Q mutant of cAMP-dependent protein kinase reveals unexpected apoenzyme conformation | Descriptor: | cAMP-dependent protein kinase, alpha-catalytic subunit | Authors: | Wu, J, Yang, J, Madhusudan, N, Xuong, N.H, Ten Eyck, L.F, Taylor, S.S. | Deposit date: | 2004-04-01 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the E230Q mutant of cAMP-dependent
protein kinase reveals an unexpected apoenzyme conformation and an
extended N-terminal A helix. Protein Sci., 14, 2005
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1STC
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![BU of 1stc by Molmil](/molmil-images/mine/1stc) | CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH STAUROSPORINE | Descriptor: | CAMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR, STAUROSPORINE | Authors: | Prade, L, Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | Deposit date: | 1997-10-10 | Release date: | 1998-02-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential. Structure, 5, 1997
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1NXB
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1T41
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![BU of 1t41 by Molmil](/molmil-images/mine/1t41) | Crystal structure of human aldose reductase complexed with NADP and IDD552 | Descriptor: | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [5-FLUORO-2-({[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]AMINO}CARBONYL)PHENOXY]ACETIC ACID | Authors: | Ruiz, F, Hazemann, I, Mitschler, A, Chevrier, B, Schneider, T, Joachimiak, A, Karplus, M, Podjarny, A. | Deposit date: | 2004-04-28 | Release date: | 2004-08-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48. Acta Crystallogr.,Sect.D, 60, 2004
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2GUF
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![BU of 2guf by Molmil](/molmil-images/mine/2guf) | In meso crystal structure of the cobalamin transporter, BtuB | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, FORMIC ACID, Vitamin B12 transporter btuB, ... | Authors: | Caffrey, M, Cherezov, V, Yamashita, E, Cramer, W.A. | Deposit date: | 2006-04-29 | Release date: | 2006-12-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | In Meso Structure of the Cobalamin Transporter, BtuB, at 1.95 A Resolution. J.Mol.Biol., 364, 2006
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1OAT
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![BU of 1oat by Molmil](/molmil-images/mine/1oat) | ORNITHINE AMINOTRANSFERASE | Descriptor: | ORNITHINE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Shen, B.W, Schirmer, T, Jansonius, J.N. | Deposit date: | 1997-03-26 | Release date: | 1998-04-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of human recombinant ornithine aminotransferase. J.Mol.Biol., 277, 1998
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1O1S
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![BU of 1o1s by Molmil](/molmil-images/mine/1o1s) | Structure of FPT bound to isoprenoid analog 3b | Descriptor: | (2E,6E)-8-[(3-BENZOYLBENZYL)OXY]-3,7-DIMETHYLOCTA-2,6-DIENYL TRIHYDROGEN DIPHOSPHATE, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ... | Authors: | Turek-Etienne, T.C, Strickland, C.L, Distefano, M.D. | Deposit date: | 2003-01-14 | Release date: | 2003-05-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Biochemical and Structural Studies with Prenyl Diphosphate Analogues Provide Insights into
Isoprenoid Recognition by Protein Farnesyl Transferase Biochemistry, 42, 2003
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1SDK
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![BU of 1sdk by Molmil](/molmil-images/mine/1sdk) | CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A | Descriptor: | 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ... | Authors: | Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G. | Deposit date: | 1996-02-26 | Release date: | 1996-08-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Allosteric transition intermediates modelled by crosslinked haemoglobins. Nature, 375, 1995
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1SIR
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![BU of 1sir by Molmil](/molmil-images/mine/1sir) | The Crystal Structure and Mechanism of Human Glutaryl-CoA Dehydrogenase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase, S-4-NITROBUTYRYL-COA | Authors: | Wang, M, Fu, Z, Paschke, R, Goodman, S.L, Frerman, F.E, Kim, J.J. | Deposit date: | 2004-03-01 | Release date: | 2004-09-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions Biochemistry, 43, 2004
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1SQ7
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![BU of 1sq7 by Molmil](/molmil-images/mine/1sq7) | Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase | Descriptor: | Triosephosphate isomerase | Authors: | Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K. | Deposit date: | 2004-03-18 | Release date: | 2004-08-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase Protein Eng.Des.Sel., 17, 2004
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1O4S
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1SQK
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![BU of 1sqk by Molmil](/molmil-images/mine/1sqk) | CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Hertzog, M, Van Heijenoort, C, Didry, D, Gaudier, M, Gigant, B, Coutant, J, Didelot, G, Preat, T, Knossow, M, Guittet, E, Carlier, M.F. | Deposit date: | 2004-03-19 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The beta-Thymosin/WH2 Domain; Structural Basis for the Switch from Inhibition to Promotion of Actin Assembly Cell(Cambridge,Mass.), 117, 2004
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2H2S
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![BU of 2h2s by Molmil](/molmil-images/mine/2h2s) | |
1O6W
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![BU of 1o6w by Molmil](/molmil-images/mine/1o6w) | |
1SM1
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![BU of 1sm1 by Molmil](/molmil-images/mine/1sm1) | COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS WITH QUINUPRISTIN AND DALFOPRISTIN | Descriptor: | 23S RIBOSOMAL RNA, 5-(2-DIETHYLAMINO-ETHANESULFONYL)-21-HYDROXY-10-ISOPROPYL-11,19-DIMETHYL-9,26-DIOXA-3,15,28-TRIAZA-TRICYCLO[23.2.1.00,255]OCTACOSA-1(27),12,17,19,25(28)-PENTAENE-2,8,14,23-TETRAONE, 50S RIBOSOMAL PROTEIN L11, ... | Authors: | Harms, J.M, Schluenzen, F, Fucini, P, Bartels, H, Yonath, A. | Deposit date: | 2004-03-08 | Release date: | 2004-08-03 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (3.42 Å) | Cite: | Alterations at the Peptidyl Transferase Centre of the Ribosome Induced by the Synergistic Action of the Streptogramins Dalfopristin and Quinupristin. Bmc Biol., 2, 2004
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1S2C
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![BU of 1s2c by Molmil](/molmil-images/mine/1s2c) | Crystal structures of prostaglandin D2 11-ketoreductase in complex with the non-steroidal anti-inflammatory drugs flufenamic acid and indomethacin | Descriptor: | 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, Aldo-keto reductase family 1 member C3, DIMETHYL SULFOXIDE, ... | Authors: | Lovering, A.L, Ride, J.P, Bunce, C.M, Desmond, J.C, Cummings, S.M, White, S.A. | Deposit date: | 2004-01-08 | Release date: | 2004-03-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of prostaglandin D(2) 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin. Cancer Res., 64, 2004
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1SPQ
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![BU of 1spq by Molmil](/molmil-images/mine/1spq) | Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase | Descriptor: | DI(HYDROXYETHYL)ETHER, Triosephosphate isomerase | Authors: | Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K. | Deposit date: | 2004-03-17 | Release date: | 2004-08-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase Protein Eng.Des.Sel., 17, 2004
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1NMM
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![BU of 1nmm by Molmil](/molmil-images/mine/1nmm) | beta-1,4-galactosyltransferase mutant Cys342Thr complex with alpha-lactalbumin and GlcNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | Authors: | Ramakrishnan, B, Shah, P.S, Qasba, P.K. | Deposit date: | 2003-01-10 | Release date: | 2003-01-21 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc. J.Biol.Chem., 276, 2001
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1NNC
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![BU of 1nnc by Molmil](/molmil-images/mine/1nnc) | |
1NNT
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![BU of 1nnt by Molmil](/molmil-images/mine/1nnt) | |
2H8P
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![BU of 2h8p by Molmil](/molmil-images/mine/2h8p) | Structure of a K channel with an amide to ester substitution in the selectivity filter | Descriptor: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB heavy chain, FAB light chain, ... | Authors: | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | Deposit date: | 2006-06-07 | Release date: | 2006-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
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