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3K8E
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BU of 3k8e by Molmil
Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase
Descriptor: 3-deoxy-manno-octulosonate cytidylyltransferase
Authors:Heyes, D.J, Levy, C.W, Lafite, P, Scrutton, N.S, Leys, D.
Deposit date:2009-10-14
Release date:2009-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases
J.Biol.Chem., 284, 2009
1ODD
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BU of 1odd by Molmil
OMPR C-TERMINAL DOMAIN (OMPR-C) FROM ESCHERICHIA COLI
Descriptor: TRANSCRIPTIONAL REGULATORY PROTEIN OMPR
Authors:Kondou, H, Nakagawa, A, Tanaka, I.
Deposit date:1996-10-31
Release date:1997-05-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.
Nat.Struct.Biol., 4, 1997
2JVV
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BU of 2jvv by Molmil
Solution Structure of E. coli NusG carboxyterminal domain
Descriptor: Transcription antitermination protein nusG
Authors:Schweimer, K, Scheckenhofer, U, Roesch, P.
Deposit date:2007-09-26
Release date:2008-10-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators.
J.Mol.Biol., 391, 2009
8TSV
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BU of 8tsv by Molmil
Crystal structure of the Zika virus stem-loop A (SLA) top stem
Descriptor: GLYCEROL, SULFATE ION, Zika virus stem-loop A (SLA) top stem
Authors:Tipo, J, Gottipati, K, Choi, K.H.
Deposit date:2023-08-11
Release date:2024-03-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:High-resolution RNA tertiary structures in Zika virus stem-loop A for the development of inhibitory small molecules.
Rna, 30, 2024
8TQX
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BU of 8tqx by Molmil
Crystal structure of the Zika virus stem-loop A (SLA) bottom stem
Descriptor: GLYCEROL, MAGNESIUM ION, Zika virus stem-loop A (SLA) bottom stem
Authors:Tipo, J, Gottipati, K, Choi, K.H.
Deposit date:2023-08-08
Release date:2024-03-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:High-resolution RNA tertiary structures in Zika virus stem-loop A for the development of inhibitory small molecules.
Rna, 30, 2024
2K06
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BU of 2k06 by Molmil
Solution structure of the aminoterminal domain of E. coli NusG
Descriptor: Transcription antitermination protein nusG
Authors:Schweimer, K, Scheckenhofer, U, Roesch, P.
Deposit date:2008-01-25
Release date:2009-02-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators.
J.Mol.Biol., 391, 2009
2MZ8
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BU of 2mz8 by Molmil
Solution NMR structure of Salmonella Typhimurium transcriptional regulator protein Crl
Descriptor: Sigma factor-binding protein Crl
Authors:Cavaliere, P, Levi-Acobas, F, Monteil, V, Bellalou, J, Mayer, C, Norel, F, Sizun, C.
Deposit date:2015-02-07
Release date:2015-12-23
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Binding interface between the Salmonella sigma (S)/RpoS subunit of RNA polymerase and Crl: hints from bacterial species lacking crl.
Sci Rep, 5, 2015
4BK0
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BU of 4bk0 by Molmil
Crystal structure of the KIX domain of human RECQL5 (domain-swapped dimer)
Descriptor: ATP-DEPENDENT DNA HELICASE Q5, DI(HYDROXYETHYL)ETHER
Authors:Kassube, S.A, Jinek, M, Fang, J, Tsutakawa, S, Nogales, E.
Deposit date:2013-04-21
Release date:2013-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Mimicry in Transcription Regulation of Human RNA Polymerase II by the DNA Helicase Recql5
Nat.Struct.Mol.Biol., 20, 2013
4QVC
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BU of 4qvc by Molmil
E.coli Hfq in complex with RNA Aus
Descriptor: RNA (5'-R(*AP*U*AP*AP*CP*UP*A)-3'), RNA-binding protein Hfq
Authors:Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y.
Deposit date:2014-07-14
Release date:2015-05-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
4QVD
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BU of 4qvd by Molmil
E.coli Hfq in complex with RNA Ads
Descriptor: RNA (5'-R(*AP*AP*CP*UP*AP*AP*A)-3'), RNA-binding protein Hfq
Authors:Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y.
Deposit date:2014-07-14
Release date:2015-05-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.972 Å)
Cite:Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
8YXP
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BU of 8yxp by Molmil
Structure of mumps virus L protein (state2)
Descriptor: RNA-directed RNA polymerase L, ZINC ION
Authors:Li, T.H, Shen, Q.T.
Deposit date:2024-04-02
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structures of the mumps virus polymerase complex via cryo-electron microscopy.
Nat Commun, 15, 2024
8URB
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BU of 8urb by Molmil
Porcine epidemic diarrhea virus complete core polymerase complex
Descriptor: RNA (33-MER), RNA (55-MER), ZINC ION, ...
Authors:Anderson, T.K, Kirchdoerfer, R.N.
Deposit date:2023-10-25
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An alphacoronavirus polymerase structure reveals conserved co-factor functions.
Biorxiv, 2023
8YXL
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BU of 8yxl by Molmil
Structure of C-terminal domain of L protein from Mumps virus
Descriptor: RNA-directed RNA polymerase L
Authors:Li, T.H, Shen, Q.T.
Deposit date:2024-04-02
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structures of the mumps virus polymerase complex via cryo-electron microscopy.
Nat Commun, 15, 2024
5VVR
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BU of 5vvr by Molmil
Ternary complex of RNA Pol II, transcription scaffold and Rad26
Descriptor: DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ...
Authors:Lahiri, I, Leschziner, A.E.
Deposit date:2017-05-19
Release date:2017-11-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
6DRD
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BU of 6drd by Molmil
RNA Pol II(G)
Descriptor: DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G.
Deposit date:2018-06-11
Release date:2019-06-12
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.
Nat. Struct. Mol. Biol., 25, 2018
5VVS
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BU of 5vvs by Molmil
RNA pol II elongation complex
Descriptor: DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Lahiri, I, Leschziner, A.E.
Deposit date:2017-05-20
Release date:2017-11-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Structural basis for the initiation of eukaryotic transcription-coupled DNA repair.
Nature, 551, 2017
4W5R
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BU of 4w5r by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8 (Long Target)
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5Q
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BU of 4w5q by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5T
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BU of 4w5t by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-7
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
6XZD
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BU of 6xzd by Molmil
Influenza C virus polymerase complex without chicken ANP32A - Subclass 2
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*CP*UP*GP*C)-3'), ...
Authors:Keown, J.R, Carrique, L, Fan, H, Grimes, J.M, Fodor, E.
Deposit date:2020-02-04
Release date:2020-12-23
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
6Y0C
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BU of 6y0c by Molmil
Influenza C virus polymerase in complex with human ANP32A - Subclass 2
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*UP*UP*UP*U)-3'), ...
Authors:Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E.
Deposit date:2020-02-07
Release date:2020-11-25
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
6NIT
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BU of 6nit by Molmil
Human Argonaute2-miR-122 bound to a target RNA with four central mismatches (bu4)
Descriptor: Protein argonaute-2, RNA (5'-R(P*AP*AP*CP*AP*CP*CP*AP*UP*CP*CP*AP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
Authors:Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2018-12-31
Release date:2019-08-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Basis for Target-Directed MicroRNA Degradation.
Mol.Cell, 75, 2019
4W5O
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BU of 4w5o by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-9
Descriptor: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHENOL, ...
Authors:Schirle, N.T, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
4W5N
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BU of 4w5n by Molmil
The Crystal Structure of Human Argonaute2 Bound to a Defined Guide RNA
Descriptor: MAGNESIUM ION, PHENOL, Protein argonaute-2, ...
Authors:Schirle, N.T, Sheu-Gruttadauria, J, MacRae, I.J.
Deposit date:2014-08-18
Release date:2014-11-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Gene regulation. Structural basis for microRNA targeting.
Science, 346, 2014
7OM6
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BU of 7om6 by Molmil
Thosea asigna virus RdRP domain in complex with RNA
Descriptor: DI(HYDROXYETHYL)ETHER, RNA (5'-R(P*AP*AP*AP*UP*UP*U)-3'), RNA-dependent RNA polymerase
Authors:Ferrero, D.S, Falqui, M, Verdaguer, N.
Deposit date:2021-05-21
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Snapshots of a Non-Canonical RdRP in Action.
Viruses, 13, 2021

222926

數據於2024-07-24公開中

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